Journal
CLINICAL INFECTIOUS DISEASES
Volume 71, Issue 7, Pages E191-E194Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa023
Keywords
influenza; favipiravir; zanamivir; genome sequencing
Categories
Funding
- Sir Henry Dale Fellowship - Wellcome Trust [101239/Z/13/Z, 101239/Z/13/A]
- Sir Henry Dale Fellowship - Royal Society [101239/Z/13/Z, 101239/Z/13/A]
- Wellcome Trust Studentship [105365/Z/14/Z]
- UCL/UCLH NIHR Biomedical Research Centre
- Isaac Newton Trust
- Wellcome Trust [101239/Z/13/A, 105365/Z/14/Z] Funding Source: Wellcome Trust
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A combination of favipiravir and zanamivir successfully cleared influenza B infection in a child who had undergone bone marrow transplant for X-linked severe combined immunodeficiency, with no recovery of T lymphocytes. Deep sequencing of viral samples illuminated the within-host dynamics of infection, demonstrating the effectiveness of favipiravir in this case.
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