- Home
- Publications
- Publication Search
- Publication Details
Title
Plasma Membrane Pores Drive Inflammatory Cell Death
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-08-21
DOI
10.3389/fcell.2020.00817
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke
- (2020) Masanori Gomi Naito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation
- (2020) Xiaoru Duan et al. Cell Death & Disease
- RIPK3 collaborates with GSDMD to drive tissue injury in lethal polymicrobial sepsis
- (2020) Hui Chen et al. CELL DEATH AND DIFFERENTIATION
- Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation
- (2020) Michael Devos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)
- (2020) Shelbi Christgen et al. Frontiers in Cellular and Infection Microbiology
- Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y12 signaling pathway
- (2020) Bo Huang et al. Cellular & Molecular Immunology
- New mechanism of nerve injury in Alzheimer’s disease: β‐amyloid‐induced neuronal pyroptosis
- (2020) Chenyang Han et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
- (2020) Andre L. Samson et al. Nature Communications
- Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
- (2020) Katherine A. Davies et al. Nature Communications
- A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
- (2020) Joanne M. Hildebrand et al. Nature Communications
- TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma
- (2019) Biswajit Podder et al. CELL DEATH AND DIFFERENTIATION
- The molecular machinery of regulated cell death
- (2019) Daolin Tang et al. CELL RESEARCH
- Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing
- (2019) Kazuhito Sai et al. JOURNAL OF CELL BIOLOGY
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
- (2019) Sabrina Sofia Burgener et al. Cell Reports
- ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)
- (2019) R. K. Subbarao Malireddi et al. Frontiers in Cellular and Infection Microbiology
- Fiery Cell Death: Pyroptosis in the Central Nervous System
- (2019) Brienne A. McKenzie et al. TRENDS IN NEUROSCIENCES
- Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
- (2018) Nathalia M. de Vasconcelos et al. CELL DEATH AND DIFFERENTIATION
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice
- (2018) Rosalie Heilig et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Necroptosis in development and diseases
- (2018) Bing Shan et al. GENES & DEVELOPMENT
- RIP kinase 1–dependent endothelial necroptosis underlies systemic inflammatory response syndrome
- (2018) Matija Zelic et al. JOURNAL OF CLINICAL INVESTIGATION
- TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
- (2018) R.K. Subbarao Malireddi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
- (2018) Emma J. Petrie et al. Nature Communications
- Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death
- (2018) Hiroto Kambara et al. Cell Reports
- Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation
- (2018) Shui-Xing Yu et al. Frontiers in Immunology
- Cryo-EM structure of the gasdermin A3 membrane pore
- (2018) Jianbin Ruan et al. NATURE
- Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming
- (2018) Jack P. Green et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
- (2018) Joseph Sarhan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
- (2018) Pontus Orning et al. SCIENCE
- Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
- (2017) Si Ming Man et al. IMMUNOLOGICAL REVIEWS
- Insane in the membrane: a structural perspective of MLKL function in necroptosis
- (2017) Emma J Petrie et al. IMMUNOLOGY AND CELL BIOLOGY
- ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death
- (2017) Sannula Kesavardhana et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D
- (2017) Kimberley D. Gutierrez et al. JOURNAL OF IMMUNOLOGY
- NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
- (2017) Zhen Qiu et al. Oxidative Medicine and Cellular Longevity
- Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis
- (2017) Siyun Kuang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
- (2017) Stephanie A. Conos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation
- (2017) Tiantian Tang et al. Nature Communications
- RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
- (2017) Yingying Zhang et al. Nature Communications
- XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
- (2017) Kate E. Lawlor et al. Cell Reports
- Necroptosis Execution Is Mediated by Plasma Membrane Nanopores Independent of Calcium
- (2017) Uris Ros et al. Cell Reports
- β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares
- (2017) Emily L. Goldberg et al. Cell Reports
- RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus
- (2016) Shoko Nogusa et al. Cell Host & Microbe
- MLKL forms cation channels
- (2016) Bingqing Xia et al. CELL RESEARCH
- Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
- (2016) Xin Chen et al. CELL RESEARCH
- GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
- (2016) Lorenzo Sborgi et al. EMBO JOURNAL
- An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice
- (2016) Isis Ludwig-Portugall et al. KIDNEY INTERNATIONAL
- Pore-forming activity and structural autoinhibition of the gasdermin family
- (2016) Jingjin Ding et al. NATURE
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
- (2016) Yuan He et al. NATURE
- Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
- (2016) Boris Strilic et al. NATURE
- Necroptosis in development, inflammation and disease
- (2016) Ricardo Weinlich et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death
- (2016) A V Jacobsen et al. Cell Death & Disease
- Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis
- (2016) Shrikant R. Mulay et al. Nature Communications
- Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models
- (2016) Michael J. D. Daniels et al. Nature Communications
- Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?
- (2015) Justine M. Abais et al. ANTIOXIDANTS & REDOX SIGNALING
- Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis
- (2015) D A Rodriguez et al. CELL DEATH AND DIFFERENTIATION
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Necroptosis and its role in inflammation
- (2015) Manolis Pasparakis et al. NATURE
- The diverse role of RIP kinases in necroptosis and inflammation
- (2015) John Silke et al. NATURE IMMUNOLOGY
- Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
- (2015) Seokwon Kang et al. Nature Communications
- RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
- (2015) Kate E. Lawlor et al. Nature Communications
- Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage
- (2015) Kipyegon Kitur et al. PLoS Pathogens
- Bacterial Exotoxins and the Inflammasome
- (2015) Allison J. Greaney et al. Frontiers in Immunology
- The P2X7 receptor: Shifting from a low- to a high-conductance channel — An enigmatic phenomenon?
- (2014) Luiz Anastacio Alves et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction
- (2014) Mark Luedde et al. CARDIOVASCULAR RESEARCH
- NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke
- (2014) Fan Yang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
- (2014) Huayi Wang et al. MOLECULAR CELL
- Inflammatory caspases are innate immune receptors for intracellular LPS
- (2014) Jianjin Shi et al. NATURE
- Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense
- (2014) X. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
- (2014) Joanne M. Hildebrand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
- (2014) Yves Dondelinger et al. Cell Reports
- XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation
- (2014) Monica Yabal et al. Cell Reports
- Necroptosis: is there a role for mitochondria?
- (2014) Kurt D. Marshall et al. Frontiers in Physiology
- Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death
- (2013) Xin Chen et al. CELL RESEARCH
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
- (2013) James M. Murphy et al. IMMUNITY
- Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
- (2013) Zhenyu Cai et al. NATURE CELL BIOLOGY
- Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
- (2013) A. Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA
- (2012) Jason W. Upton et al. Cell Host & Microbe
- Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
- (2012) James E. Vince et al. IMMUNITY
- Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome
- (2012) Tae-Bong Kang et al. IMMUNITY
- Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury
- (2012) Andreas Linkermann et al. KIDNEY INTERNATIONAL
- Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
- (2012) Nirmal Robinson et al. NATURE IMMUNOLOGY
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- Identification of RIP1 kinase as a specific cellular target of necrostatins
- (2008) Alexei Degterev et al. Nature Chemical Biology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started