Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
Authors
Keywords
-
Journal
Nature Communications
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-06-24
DOI
10.1038/ncomms8515
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A20 Restricts Ubiquitination of Pro-Interleukin-1β Protein Complexes and Suppresses NLRP3 Inflammasome Activity
- (2015) Bao H. Duong et al. IMMUNITY
- RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
- (2015) Kate E. Lawlor et al. Nature Communications
- RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
- (2014) James A. Rickard et al. CELL
- RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
- (2014) Christopher P. Dillon et al. CELL
- Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
- (2014) Alvin Lu et al. CELL
- RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
- (2014) S Orozco et al. CELL DEATH AND DIFFERENTIATION
- Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization and K+Efflux
- (2014) Luigi Franchi et al. JOURNAL OF IMMUNOLOGY
- FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
- (2014) P. Gurung et al. JOURNAL OF IMMUNOLOGY
- RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity
- (2014) Pratyusha Mandal et al. MOLECULAR CELL
- RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
- (2014) Xiaqiong Wang et al. NATURE IMMUNOLOGY
- RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
- (2014) W. J. Kaiser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis
- (2014) K. Newton et al. SCIENCE
- A Plug Release Mechanism for Membrane Permeation by MLKL
- (2014) Lijing Su et al. STRUCTURE
- Coinfection in acute gastroenteritis predicts a more severe clinical course in children
- (2013) D. Valentini et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
- (2013) James M. Murphy et al. IMMUNITY
- Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL
- (2013) William J. Kaiser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome
- (2013) T. Fernandes-Alnemri et al. JOURNAL OF IMMUNOLOGY
- IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation
- (2013) K.-M. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synergistic Effects Between Rotavirus and Coinfecting Pathogens on Diarrheal Disease: Evidence from a Community-based Study in Northwestern Ecuador
- (2012) D. Bhavnani et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
- (2012) James E. Vince et al. IMMUNITY
- Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome
- (2012) Tae-Bong Kang et al. IMMUNITY
- Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
- (2012) Christine Juliana et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Survival Function of the FADD-CASPASE-8-cFLIPL Complex
- (2012) Christopher P. Dillon et al. Cell Reports
- The NLRP3 Inflammasome Detects Encephalomyocarditis Virus and Vesicular Stomatitis Virus Infection
- (2011) J. V. Rajan et al. JOURNAL OF VIROLOGY
- RIP3 mediates the embryonic lethality of caspase-8-deficient mice
- (2011) William J. Kaiser et al. NATURE
- Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
- (2011) Andrew Oberst et al. NATURE
- Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
- (2011) S. He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the NLRP3 inflammasome by intracellular poly I:C
- (2010) Jayant V. Rajan et al. FEBS LETTERS
- Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes
- (2010) Jianghong Wu et al. JOURNAL OF CLINICAL IMMUNOLOGY
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress
- (2009) Luke A. J. O'Neill IMMUNOLOGICAL REVIEWS
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
- (2009) Naotada Ishihara et al. NATURE CELL BIOLOGY
- The NLR Gene Family: A Standard Nomenclature
- (2008) Jenny P.-Y. Ting et al. IMMUNITY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started