XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation

Published 2017 View Full Article

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Title
XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
Authors
Keywords
Toll-like receptor, NLRP3, RIPK3, caspase-8, TNFR2, XIAP, cIAP1, necroptosis, interferon, autoinflammatory disease
Journal
Cell Reports
Volume 20, Issue 3, Pages 668-682
Publisher
Elsevier BV
Online
2017-07-19
DOI
10.1016/j.celrep.2017.06.073

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