Targeting Cancer Associated Fibroblasts in Liver Fibrosis and Liver Cancer Using Nanocarriers
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting Cancer Associated Fibroblasts in Liver Fibrosis and Liver Cancer Using Nanocarriers
Authors
Keywords
-
Journal
Cells
Volume 9, Issue 9, Pages 2027
Publisher
MDPI AG
Online
2020-09-03
DOI
10.3390/cells9092027
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Fibroblasts in urothelial bladder cancer define stroma phenotypes that are associated with clinical outcome
- (2020) Artur Mezheyeuski et al. Scientific Reports
- The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma
- (2020) Haiyu Wang et al. Frontiers in Cell and Developmental Biology
- Fibrosis and cancer: A strained relationship
- (2020) Bram Piersma et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Hyperbranched lipoid-based lipid nanoparticles for bidirectional regulation of collagen accumulation in liver fibrosis
- (2020) Jian-Bin Qiao et al. JOURNAL OF CONTROLLED RELEASE
- Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma
- (2020) Richard S. Finn et al. NEW ENGLAND JOURNAL OF MEDICINE
- The role of fibroblast activation protein in health and malignancy
- (2020) Allison A. Fitzgerald et al. CANCER AND METASTASIS REVIEWS
- Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
- (2020) Ying Shen et al. CANCER CELL
- Improving the Efficacy of Liver Cancer Immunotherapy: the Power of Combined Preclinical and Clinical Studies
- (2020) Gen‐Sheng Feng et al. HEPATOLOGY
- In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles
- (2020) Leonard Kaps et al. Cells
- Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled, phase 3 trial
- (2019) Andrew X Zhu et al. LANCET ONCOLOGY
- Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats
- (2019) Sabine Klein et al. Scientific Reports
- The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma
- (2019) Jacopo Baglieri et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- An integrin-based nanoparticle that targets activated hepatic stellate cells and alleviates liver fibrosis
- (2019) Yanping Li et al. JOURNAL OF CONTROLLED RELEASE
- A Phase 2 Study of Galunisertib (TGF-β1 Receptor Type I Inhibitor) and Sorafenib in Patients With Advanced Hepatocellular Carcinoma
- (2019) R.K. Kelley et al. Clinical and Translational Gastroenterology
- Multiplex quantitative analysis of cancer-associated fibroblasts and immunotherapy outcome in metastatic melanoma
- (2019) Pok Fai Wong et al. Journal for ImmunoTherapy of Cancer
- Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy
- (2019) Tongyan Liu et al. Journal of Hematology & Oncology
- The role of collagen in cancer: from bench to bedside
- (2019) Shuaishuai Xu et al. Journal of Translational Medicine
- A global view of hepatocellular carcinoma: trends, risk, prevention and management
- (2019) Ju Dong Yang et al. Nature Reviews Gastroenterology & Hepatology
- Pharmacokinetics of a sustained release formulation of PDGFβ-receptor directed carrier proteins to target the fibrotic liver
- (2018) F. van Dijk et al. JOURNAL OF CONTROLLED RELEASE
- Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial
- (2018) Masatoshi Kudo et al. LANCET
- Liver fibrosis: Direct antifibrotic agents and targeted therapies
- (2018) Detlef Schuppan et al. MATRIX BIOLOGY
- Cell type-specific pharmacological kinase inhibition for cancer chemoprevention
- (2018) Manjeet Deshmukh et al. Nanomedicine-Nanotechnology Biology and Medicine
- Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma
- (2018) Yusheng Cheng et al. Cell Death & Disease
- The role of osteopontin in the progression of solid organ tumour
- (2018) Hailin Zhao et al. Cell Death & Disease
- The immune contexture of hepatocellular carcinoma predicts clinical outcome
- (2018) Friedrich Foerster et al. Scientific Reports
- Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development
- (2018) Yun-Chieh Sung et al. Theranostics
- The Expression of FAP in Hepatocellular Carcinoma Cells is Induced by Hypoxia and Correlates with Poor Clinical Outcomes
- (2018) Baojia Zou et al. Journal of Cancer
- Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis
- (2018) Isabel Fabregat et al. Frontiers in Oncology
- TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives
- (2018) Serena Mancarella et al. SEMINARS IN LIVER DISEASE
- SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles
- (2017) Nadine Leber et al. JOURNAL OF CONTROLLED RELEASE
- The nature and biology of basement membranes
- (2017) Ambra Pozzi et al. MATRIX BIOLOGY
- Osteopontin at the Crossroads of Inflammation and Tumor Progression
- (2017) Luigi Mario Castello et al. MEDIATORS OF INFLAMMATION
- pPB Peptide-Mediated siRNA-Loaded Stable Nucleic Acid Lipid Nanoparticles on Targeting Therapy of Hepatic Fibrosis
- (2017) Zongxiang Jia et al. MOLECULAR PHARMACEUTICS
- Roles of Fibroblast Activation Protein and Hepatocyte Growth Factor Expressions in Angiogenesis and Metastasis of Gastric Cancer
- (2017) Li-Ming Gao et al. PATHOLOGY & ONCOLOGY RESEARCH
- Prognostic significance of tumor-associated macrophages in breast cancer: a meta-analysis of the literature
- (2017) Xixi Zhao et al. Oncotarget
- Tumor Microenvironment and Differential Responses to Therapy
- (2017) Eishu Hirata et al. Cold Spring Harbor Perspectives in Medicine
- TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
- (2017) Nina D. Thiele et al. Scientific Reports
- FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3–CCL2 Signaling
- (2016) Xuguang Yang et al. CANCER RESEARCH
- Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
- (2016) Philippe Gascard et al. GENES & DEVELOPMENT
- The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury
- (2016) Xin M Wang et al. IMMUNOLOGY AND CELL BIOLOGY
- Prognostic value of polarized macrophages in patients with hepatocellular carcinoma after curative resection
- (2016) Qing-Hua Shu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Role of epithelial to mesenchymal transition in hepatocellular carcinoma
- (2016) Gianluigi Giannelli et al. JOURNAL OF HEPATOLOGY
- Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases
- (2016) Y. Wang et al. MOLECULAR NEUROBIOLOGY
- Tumor-associated fibroblasts predominantly come from local and not circulating precursors
- (2016) Ainhoa Arina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cancer-associated fibroblasts in hepatocellular carcinoma
- (2016) Norio Kubo et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2
- (2016) Yaping Xu et al. Oncotarget
- Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling
- (2016) Feng Liu et al. Scientific Reports
- Novel insights into the function and dynamics of extracellular matrix in liver fibrosis
- (2015) Morten A. Karsdal et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Hepatic stellate cells: central modulators of hepatic carcinogenesis
- (2015) Alexandra I Thompson et al. BMC GASTROENTEROLOGY
- Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis
- (2015) Zhen-Wei Peng et al. HEPATOLOGY
- Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis
- (2015) Carolina Jiménez Calvente et al. HEPATOLOGY
- Hepatic stellate cell and monocyte interaction contributes to poor prognosis in hepatocellular carcinoma
- (2015) Juling Ji et al. HEPATOLOGY
- Combination cancer immunotherapy and new immunomodulatory targets
- (2015) Kathleen M. Mahoney et al. NATURE REVIEWS DRUG DISCOVERY
- TIMP-1 activated carcinoma-associated fibroblasts inhibit tumor apoptosis by activating SDF1/CXCR4 signaling in hepatocellular carcinoma
- (2015) Tao Song et al. Oncotarget
- In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles
- (2015) Leonard Kaps et al. Advanced Healthcare Materials
- Cancer Associated Fibroblasts in Stage I-IIIA NSCLC: Prognostic Impact and Their Correlations with Tumor Molecular Markers
- (2015) Thomas K. Kilvaer et al. PLoS One
- Non-collagenous ECM proteins in blood vessel morphogenesis and cancer
- (2014) Vassiliki Kostourou et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Activated Human Hepatic Stellate Cells Promote Growth of Human Hepatocellular Carcinoma in a Subcutaneous Xenograft Nude Mouse Model
- (2014) Zhi-min Geng et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells
- (2014) Shanshan Wan et al. GASTROENTEROLOGY
- Role of activated hepatic stellate cells in proliferation and metastasis of hepatocellular carcinoma
- (2014) Nan Lin et al. HEPATOLOGY RESEARCH
- Interferon gamma peptidomimetic targeted to hepatic stellate cells ameliorates acute and chronic liver fibrosis in vivo
- (2014) Ruchi Bansal et al. JOURNAL OF CONTROLLED RELEASE
- Hepatic stellate cells and extracellular matrix in hepatocellular carcinoma: more complicated than ever
- (2014) Vinicio Carloni et al. LIVER INTERNATIONAL
- Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma
- (2014) H Wang et al. Cell Death & Disease
- Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation
- (2013) Kaori Kuramitsu et al. AMERICAN JOURNAL OF PATHOLOGY
- Targeting the HGF/c-MET Pathway in Hepatocellular Carcinoma
- (2013) L. Goyal et al. CLINICAL CANCER RESEARCH
- Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma
- (2013) Virginia Hernandez–Gea et al. GASTROENTEROLOGY
- Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma
- (2013) Shuhei Yoshida et al. HEPATOLOGY
- Evolving therapies for liver fibrosis
- (2013) Detlef Schuppan et al. JOURNAL OF CLINICAL INVESTIGATION
- Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion
- (2013) Bastian Höchst et al. JOURNAL OF HEPATOLOGY
- Enhanced Effectivity of an ALK5-Inhibitor after Cell-Specific Delivery to Hepatic Stellate Cells in Mice with Liver Injury
- (2013) Marike Marjolijn van Beuge et al. PLoS One
- TIMP-1 Promotes Accumulation of Cancer Associated Fibroblasts and Cancer Progression
- (2013) Yixuan Gong et al. PLoS One
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs
- (2013) Fiona M. Keane et al. FEBS Open Bio
- Cationic Nanohydrogel Particles as Potential siRNA Carriers for Cellular Delivery
- (2012) Lutz Nuhn et al. ACS Nano
- Selective Targeting of Interferon to Stromal Fibroblasts and Pericytes as a Novel Therapeutic Approach to Inhibit Angiogenesis and Tumor Growth
- (2012) R. Bansal et al. MOLECULAR CANCER THERAPEUTICS
- Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
- (2011) Michael Quante et al. CANCER CELL
- Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice
- (2011) Ruchi Bansal et al. HEPATOLOGY
- Hepatic stellate cells: Partners in crime for liver metastases?
- (2011) Ningling Kang et al. HEPATOLOGY
- Identification of osteopontin as a novel marker for early hepatocellular carcinoma
- (2011) Sufen Shang et al. HEPATOLOGY
- Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice
- (2011) Wenxiu Zhao et al. INTERNATIONAL JOURNAL OF CANCER
- Effects of interferon-gamma liposomes targeted to platelet-derived growth factor receptor–beta on hepatic fibrosis in rats
- (2011) Feng Li et al. JOURNAL OF CONTROLLED RELEASE
- HCC and angiogenesis: possible targets and future directions
- (2011) Andrew X. Zhu et al. Nature Reviews Clinical Oncology
- Focal Adhesion Assembly in Myofibroblasts Fosters a Microenvironment that Promotes Tumor Growth
- (2010) Ningling Kang et al. AMERICAN JOURNAL OF PATHOLOGY
- Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Dead or Alive?
- (2010) Yury Popov et al. GASTROENTEROLOGY
- Peritumoral Activated Hepatic Stellate Cells Predict Poor Clinical Outcome in Hepatocellular Carcinoma After Curative Resection
- (2009) Min-Jie Ju et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Targeting the transforming growth factor-β signaling pathway in human cancer
- (2009) Nagathihalli S Nagaraj et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Pharmacological inhibition of integrin αvβ3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis
- (2009) Eleonora Patsenker et al. HEPATOLOGY
- Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats
- (2009) Montserrat Moreno et al. HEPATOLOGY
- Tumor-targeted intracellular delivery of anticancer drugs through the mannose-6-phosphate/insulin-like growth factor II receptor
- (2009) Jai Prakash et al. INTERNATIONAL JOURNAL OF CANCER
- TGFβ in Cancer
- (2008) Joan Massagué CELL
- A New Population of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Induces CD4+CD25+Foxp3+ T Cells
- (2008) Bastian Hoechst et al. GASTROENTEROLOGY
- Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis
- (2008) Kojiro Taura et al. GASTROENTEROLOGY
- Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
- (2008) Alessia Omenetti et al. JOURNAL OF CLINICAL INVESTIGATION
- Liver cirrhosis
- (2008) Detlef Schuppan et al. LANCET
- Resolution of liver cirrhosis using vitamin A–coupled liposomes to deliver siRNA against a collagen-specific chaperone
- (2008) Yasushi Sato et al. NATURE BIOTECHNOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started