In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles

Corona-Directed Nucleic Acid Delivery into Hepatic Stellate Cells for Liver Fibrosis Therapy

(2015) Zhengping Zhang et al.   ACS Nano

Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis

(2015) Carolina Jiménez Calvente et al.   HEPATOLOGY

Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine

(2015) Elise Lepeltier et al.   Nanomedicine

Antifibrotic Therapies in the Liver

(2015) D. Schuppan et al.   SEMINARS IN LIVER DISEASE

Liver fibrosis: Common mechanisms and antifibrotic therapies

(2015) Detlef Schuppan   Clinics and Research in Hepatology and Gastroenterology

Size-Dependent Knockdown Potential of siRNA-Loaded Cationic Nanohydrogel Particles

(2014) Lutz Nuhn et al.   BIOMACROMOLECULES

Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum

(2014) Lutz Nuhn et al.   BIOMACROMOLECULES

Polymer therapeutics: Top 10 selling pharmaceuticals — What next?

(2014) Ruth Duncan   JOURNAL OF CONTROLLED RELEASE

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Degradable Cationic Nanohydrogel Particles for Stimuli-Responsive Release of siRNA

(2014) Lutz Nuhn et al.   MACROMOLECULAR RAPID COMMUNICATIONS

New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes

(2014) Bettina Krieg et al.   PHARMACEUTICAL RESEARCH

Nanotechnology applications for the therapy of liver fibrosis

(2014) Lydia Giannitrapani   WORLD JOURNAL OF GASTROENTEROLOGY

CpG-Loaded Multifunctional Cationic Nanohydrogel Particles as Self-Adjuvanting Glycopeptide Antitumor Vaccines

(2014) Sebastian Hartmann et al.   Advanced Healthcare Materials

Cationic Polymer Nanoparticles and Nanogels: From Synthesis to Biotechnological Applications

(2013) Jose Ramos et al.   CHEMICAL REVIEWS

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Image analysis of liver collagen using sirius red is more accurate and correlates better with serum fibrosis markers than trichrome

(2013) Yi Huang et al.   LIVER INTERNATIONAL

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Cationic Nanohydrogel Particles as Potential siRNA Carriers for Cellular Delivery

(2012) Lutz Nuhn et al.   ACS Nano

Targeted Polymeric Micelles for siRNA Treatment of Experimental Cancer by Intravenous Injection

(2012) R. James Christie et al.   ACS Nano

Polycation-based nanoparticle delivery of RNAi therapeutics: Adverse effects and solutions

(2012) Borja Ballarín-González et al.   ADVANCED DRUG DELIVERY REVIEWS

In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier

(2012) Broes Naeye et al.   BIOMATERIALS

Nanomedicine

(2012) Frank Caruso et al.   CHEMICAL SOCIETY REVIEWS

Structure–activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides

(2012) Thomas Fröhlich et al.   JOURNAL OF CONTROLLED RELEASE

Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane

(2012) J. E. Zuckerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifunctional Nanogels for siRNA Delivery

(2011) Michael H. Smith et al.   ACCOUNTS OF CHEMICAL RESEARCH

Supramolecular Nanodevices: From Design Validation to Theranostic Nanomedicine

(2011) Horacio Cabral et al.   ACCOUNTS OF CHEMICAL RESEARCH

Solid-Phase Synthesis of Sequence-Defined T-, i-, and U-Shape Polymers for pDNA and siRNA Delivery

(2011) David Schaffert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Effect of Polymer Structure on Micelles Formed between siRNA and Cationic Block Copolymer Comprising Thiols and Amidines

(2011) R. James Christie et al.   BIOMACROMOLECULES

Tissue Transglutaminase Does Not Affect Fibrotic Matrix Stability or Regression of Liver Fibrosis in Mice

(2011) Yury Popov et al.   GASTROENTEROLOGY

Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers

(2011) Claudia Scholz et al.   JOURNAL OF CONTROLLED RELEASE

Nanotechnology for therapy and imaging of liver diseases

(2011) L. Harivardhan Reddy et al.   JOURNAL OF HEPATOLOGY

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

(2011) Daniel J. Siegwart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PEGylation of biodegradable dextran nanogels for siRNA delivery

(2010) B. Naeye et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Biodegradable Dextran Nanogels for RNA Interference: Focusing on Endosomal Escape and Intracellular siRNA Delivery

(2009) Koen Raemdonck et al.   ADVANCED FUNCTIONAL MATERIALS

Nanomedicine-Challenge and Perspectives

(2009) Kristina Riehemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NIR dyes for bioimaging applications

(2009) Jorge O Escobedo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

(2009) Karlin Raja Karlmark et al.   HEPATOLOGY

Tumour-targeted nanomedicines: principles and practice

(2008) T Lammers et al.   BRITISH JOURNAL OF CANCER

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET