Hydrogels: The Next Generation Body Materials for Microfluidic Chips?

Human‐on‐Leaf‐Chip: A Biomimetic Vascular System Integrated with Chamber‐Specific Organs

(2020) Mao Mao et al.   Small

All-Aqueous Phase Microfluidics for Cell Encapsulation

(2019) Kaixuan Zhu et al.   ACS Applied Materials & Interfaces

Microfluidic Electrospray Niacin Metal-Organic Frameworks Encapsulated Microcapsules for Wound Healing

(2019) Guopu Chen et al.   Research

Advances in Hydrogels in Organoids and Organs‐on‐a‐Chip

(2019) Haitao Liu et al.   ADVANCED MATERIALS

Microfluidics and hydrogel: A powerful combination

(2019) Carla B. Goy et al.   REACTIVE & FUNCTIONAL POLYMERS

Microfluidic Generation of Nanomaterials for Biomedical Applications

(2019) Xin Zhao et al.   Small

NK-Cell-Encapsulated Porous Microspheres via Microfluidic Electrospray for Tumor Immunotherapy

(2019) Dan Wu et al.   ACS Applied Materials & Interfaces

Micro/nanofabrication of brittle hydrogels using 3D printed soft ultrafine fiber molds for damage-free demolding

(2019) Shang Lv et al.   Biofabrication

Geomaterial‐Functionalized Microfluidic Devices Using a Universal Surface Modification Approach

(2019) Yaqi Zhang et al.   Advanced Materials Interfaces

Inner Surface Design of Functional Microchannels for Microscale Flow Control

(2019) Shuli Wang et al.   Small

Projection-Based 3D Printing of Cell Patterning Scaffolds with Multiscale Channels

(2018) Dai Xue et al.   ACS Applied Materials & Interfaces

Complex 3D-Printed Microchannels within Cell-Degradable Hydrogels

(2018) Kwang Hoon Song et al.   ADVANCED FUNCTIONAL MATERIALS

Paper supported long-term 3D liver co-culture model for the assessment of hepatotoxic drugs

(2018) Yaqing Wang et al.   Toxicology Research

A Biomimetic Human Gut-on-a-Chip for Modeling Drug Metabolism in Intestine

(2018) Yaqiong Guo et al.   ARTIFICIAL ORGANS

Vessel-on-a-chip with Hydrogel-based Microfluidics

(2018) Jing Nie et al.   Small

Electro-Assisted Bioprinting of Low-Concentration GelMA Microdroplets

(2018) Mingjun Xie et al.   Small

Facile Engineering of Long-Term Culturable Ex Vivo Vascularized Tissues Using Biologically Derived Matrices

(2018) Michael Hu et al.   Advanced Healthcare Materials

Coaxial Cell Printing of Freestanding, Perfusable, and Functional In Vitro Vascular Models for Recapitulation of Native Vascular Endothelium Pathophysiology

(2018) Ge Gao et al.   Advanced Healthcare Materials

Bioprinting of three-dimensional culture models and organ-on-a-chip systems

(2017) Yan Yan Shery Huang et al.   MRS BULLETIN

Bio-inspired self-healing structural color hydrogel

(2017) Fanfan Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Customization of 3D Integrated Microfluidic Chips via Modular Structure-Based Design

(2017) Jingjiang Qiu et al.   ACS Biomaterials-Science & Engineering

From Microfluidic Paper-Based Analytical Devices to Paper-Based Biofluidics with Integrated Continuous Perfusion

(2017) Yan Wu et al.   ACS Biomaterials-Science & Engineering

3D Bioprinting of Vessel-like Structures with Multilevel Fluidic Channels

(2017) Qing Gao et al.   ACS Biomaterials-Science & Engineering

Rapid Customization of 3D Integrated Microfluidic Chips via Modular Structure-Based Design

(2017) Jingjiang Qiu et al.   ACS Biomaterials Science & Engineering

From Microfluidic Paper-Based Analytical Devices to Paper-Based Biofluidics with Integrated Continuous Perfusion

(2017) Yan Wu et al.   ACS Biomaterials Science & Engineering

3D Bioprinting of Vessel-like Structures with Multilevel Fluidic Channels

(2017) Qing Gao et al.   ACS Biomaterials Science & Engineering

Interplay between materials and microfluidics

(2017) Xu Hou et al.   Nature Reviews Materials

Shape-Changing Photodegradable Hydrogels for Dynamic 3D Cell Culture

(2016) Elli Käpylä et al.   ACS Applied Materials & Interfaces

Microfluidic fabrication of bioactive microgels for rapid formation and enhanced differentiation of stem cell spheroids

(2016) Christian Siltanen et al.   Acta Biomaterialia

Effects of shear stress on endothelial cells: go with the flow

(2016) D. A. Chistiakov et al.   Acta Physiologica

A Generalizable Strategy for the 3D Bioprinting of Hydrogels from Nonviscous Photo-crosslinkable Inks

(2016) Liliang Ouyang et al.   ADVANCED MATERIALS

Direct 3D bioprinting of perfusable vascular constructs using a blend bioink

(2016) Weitao Jia et al.   BIOMATERIALS

Prevascularization in tissue engineering: Current concepts and future directions

(2016) Matthias W. Laschke et al.   BIOTECHNOLOGY ADVANCES

Gel integration for microfluidic applications

(2016) Xuanqi Zhang et al.   LAB ON A CHIP

Cell-laden microfluidic microgels for tissue regeneration

(2016) Weiqian Jiang et al.   LAB ON A CHIP

Bioprinted thrombosis-on-a-chip

(2016) Yu Shrike Zhang et al.   LAB ON A CHIP

One-step fabrication of an organ-on-a-chip with spatial heterogeneity using a 3D bioprinting technology

(2016) Hyungseok Lee et al.   LAB ON A CHIP

Fabrication of circular microfluidic network in enzymatically-crosslinked gelatin hydrogel

(2016) Jiankang He et al.   Materials Science & Engineering C-Materials for Biological Applications

Three-dimensional bioprinting of thick vascularized tissues

(2016) David B. Kolesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D Printed Paper-Based Microfluidic Analytical Devices

(2016) Yong He et al.   Micromachines

Rapid 3D Extrusion of Synthetic Tumor Microenvironments

(2015) Joshua M. Grolman et al.   ADVANCED MATERIALS

3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

(2015) Sungmin Hong et al.   ADVANCED MATERIALS

Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels

(2015) Kan Yue et al.   BIOMATERIALS

Coaxial nozzle-assisted 3D bioprinting with built-in microchannels for nutrients delivery

(2015) Qing Gao et al.   BIOMATERIALS

Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

(2015) Skarphedinn Halldorsson et al.   BIOSENSORS & BIOELECTRONICS

Hydrogels for Engineering of Perfusable Vascular Networks

(2015) Juan Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Dual-Responsive Hydrogels for Direct-Write 3D Printing

(2015) Musan Zhang et al.   MACROMOLECULES

Angiogenesis Revisited: An Overlooked Role of Endothelial Cell Metabolism in Vessel Sprouting

(2015) Saar Vandekeere et al.   MICROCIRCULATION

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

Dynamic phototuning of 3D hydrogel stiffness

(2015) Ryan S. Stowers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional bio-printing

(2015) Qi Gu et al.   Science China-Life Sciences

High-Resolution Projection Microstereolithography for Patterning of Neovasculature

(2015) Ritu Raman et al.   Advanced Healthcare Materials

Oxygen supply to encapsulated therapeutic cells

(2014) Clark K. Colton   ADVANCED DRUG DELIVERY REVIEWS

3D Bioprinting of Vascularized, Heterogeneous Cell-Laden Tissue Constructs

(2014) David B. Kolesky et al.   ADVANCED MATERIALS

Creating perfused functional vascular channels using 3D bio-printing technology

(2014) Vivian K. Lee et al.   BIOMATERIALS

Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering

(2014) Yanjiao Jiang et al.   BIOMATERIALS

Facile fabrication processes for hydrogel-based microfluidic devices made of natural biopolymers

(2014) Yuya Yajima et al.   Biomicrofluidics

Effects of bacterial communities on biofuel-producing microalgae: stimulation, inhibition and harvesting

(2014) Hui Wang et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Engineering interconnected 3D vascular networks in hydrogels using molded sodium alginate lattice as the sacrificial template

(2014) Xue-Ying Wang et al.   LAB ON A CHIP

Hydrogel bioprinted microchannel networks for vascularization of tissue engineering constructs

(2014) Luiz E. Bertassoni et al.   LAB ON A CHIP

Fluid shear stress threshold regulates angiogenic sprouting

(2014) P. A. Galie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels

(2014) Luiz E Bertassoni et al.   Biofabrication

Hydrogel microfluidics for the patterning of pluripotent stem cells

(2014) S. Cosson et al.   Scientific Reports

Microfabricated Porous Silk Scaffolds for Vascularizing Engineered Tissues

(2013) Lindsay S. Wray et al.   ADVANCED FUNCTIONAL MATERIALS

25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine

(2013) Nasim Annabi et al.   ADVANCED MATERIALS

Implementation of tetra-poly(ethylene glycol) hydrogel with high mechanical strength into microfluidic device technology

(2013) Hiroaki Takehara et al.   Biomicrofluidics

Microfluidic cell culture

(2013) Matthias Mehling et al.   CURRENT OPINION IN BIOTECHNOLOGY

A PEG-DA microfluidic device for chemotaxis studies

(2013) Mahama Aziz Traore et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Light-assisted direct-write of 3D functional biomaterials

(2013) Kolin C. Hribar et al.   LAB ON A CHIP

In Vitro Model of Tumor Cell Extravasation

(2013) Jessie S. Jeon et al.   PLoS One

Cooperative Roles of SDF-1α and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

(2013) Beum Jun Kim et al.   PLoS One

Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro

(2013) D.-H. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-Dimensional Microfluidic Collagen Hydrogels for Investigating Flow-Mediated Tumor-Endothelial Signaling and Vascular Organization

(2013) Cara F. Buchanan et al.   TISSUE ENGINEERING PART C-METHODS

Bio-Origami Hydrogel Scaffolds Composed of Photocrosslinked PEG Bilayers

(2013) Mustapha Jamal et al.   Advanced Healthcare Materials

Extrusion printing of ionic–covalent entanglement hydrogels with high toughness

(2013) Shannon E. Bakarich et al.   Journal of Materials Chemistry B

High-Throughput Printing via Microvascular Multinozzle Arrays

(2012) Christopher J. Hansen et al.   ADVANCED MATERIALS

A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers

(2012) Leon M. Bellan et al.   ADVANCED MATERIALS

Microfluidic Models of Vascular Functions

(2012) Keith H.K. Wong et al.   Annual Review of Biomedical Engineering

The integration of 3-D cell printing and mesoscopic fluorescence molecular tomography of vascular constructs within thick hydrogel scaffolds

(2012) Lingling Zhao et al.   BIOMATERIALS

Rapid and cost-effective fabrication of selectively permeable calcium-alginate microfluidic device using “modified” embedded template method

(2012) Amit Asthana et al.   Biomicrofluidics

Vascularization in Tissue Engineering: Angiogenesis versus Inosculation

(2012) M.W. Laschke et al.   EUROPEAN SURGICAL RESEARCH

Development of functional biomaterials with micro- and nanoscale technologies for tissue engineering and drug delivery applications

(2012) Hojae Bae et al.   Journal of Tissue Engineering and Regenerative Medicine

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

Vascular lumen simulation and highly-sensitive nitric oxide detection using three-dimensional gelatin chip coupled to TiC/C nanowire arrays microelectrode

(2012) Lin-Mei Li et al.   LAB ON A CHIP

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

Characterization of a microfluidic in vitro model of the blood-brain barrier (μBBB)

(2012) Ross Booth et al.   LAB ON A CHIP

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

(2012) Jordan S. Miller et al.   NATURE MATERIALS

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Building Vascular Networks

(2012) H. Bae et al.   Science Translational Medicine

Gradient-Regulated Hydrogel for Interface Tissue Engineering: Steering Simultaneous Osteo/Chondrogenesis of Stem Cells on a Chip

(2012) Xuetao Shi et al.   Advanced Healthcare Materials

Omnidirectional Printing of 3D Microvascular Networks

(2011) Willie Wu et al.   ADVANCED MATERIALS

SAM-based cell transfer to photopatterned hydrogels for microengineering vascular-like structures

(2011) Nasser Sadr et al.   BIOMATERIALS

The assembly of cell-encapsulating microscale hydrogels using acoustic waves

(2011) Feng Xu et al.   BIOMATERIALS

Solid freeform fabrication of designer scaffolds of hyaluronic acid for nerve tissue engineering

(2011) Shalu Suri et al.   BIOMEDICAL MICRODEVICES

Flow control concepts for thread-based microfluidic devices

(2011) David R. Ballerini et al.   Biomicrofluidics

Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments

(2011) Ioannis K. Zervantonakis et al.   Biomicrofluidics

Sequential assembly of cell-laden hydrogel constructs to engineer vascular-like microchannels

(2011) Yanan Du et al.   BIOTECHNOLOGY AND BIOENGINEERING

Degradation Improves Tissue Formation in (Un)Loaded Chondrocyte-laden Hydrogels

(2011) Justine J. Roberts et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Biomaterials meet microfluidics: building the next generation of artificial niches

(2011) Stefan Kobel et al.   CURRENT OPINION IN BIOTECHNOLOGY

Microfluidic Mixing: A Review

(2011) Chia-Yen Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients

(2011) Yoojin Shin et al.   LAB ON A CHIP

Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering

(2011) Bong Geun Chung et al.   LAB ON A CHIP

Customized cell microenvironments

(2011) Jennifer L. West   NATURE MATERIALS

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Microfluidic hydrogels for tissue engineering

(2011) Guo You Huang et al.   Biofabrication

Progress and Prospects for Stem Cell Engineering

(2011) Randolph S. Ashton et al.   Annual Review of Chemical and Biomolecular Engineering

Microfluidic Platforms for Studies of Angiogenesis, Cell Migration, and Cell–Cell Interactions

(2010) Seok Chung et al.   ANNALS OF BIOMEDICAL ENGINEERING

Cell-laden microengineered gelatin methacrylate hydrogels

(2010) Jason W. Nichol et al.   BIOMATERIALS

Multilayer microfluidic PEGDA hydrogels

(2010) Michael P. Cuchiara et al.   BIOMATERIALS

Pre-vascularization of in vitro three-dimensional tissues created by cell sheet engineering

(2010) Nahoko Asakawa et al.   BIOMATERIALS

Alginate-based microfluidic system for tumor spheroid formation and anticancer agent screening

(2010) Michael C. W. Chen et al.   BIOMEDICAL MICRODEVICES

Microporous cell-laden hydrogels for engineered tissue constructs

(2010) Jae Hong Park et al.   BIOTECHNOLOGY AND BIOENGINEERING

Rheological properties of peptide-based hydrogels for biomedical and other applications

(2010) Congqi Yan et al.   CHEMICAL SOCIETY REVIEWS

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

Fluid shear stress primes mouse embryonic stem cells for differentiation in a self-renewing environment via heparan sulfate proteoglycans transduction

(2010) Yi-Chin Toh et al.   FASEB JOURNAL

Regulating microenvironmental stimuli for stem cells and cancer cells using microsystems

(2010) Joong Yull Park et al.   Integrative Biology

Biological applications of microfluidic gradient devices

(2010) Sudong Kim et al.   Integrative Biology

Perfusion-based microfluidic device for three-dimensional dynamic primary human hepatocyte cell culture in the absence of biological or synthetic matrices or coagulants

(2010) Vasiliy N. Goral et al.   LAB ON A CHIP

Microchannel deformations due to solvent-induced PDMS swelling

(2010) Rémi Dangla et al.   LAB ON A CHIP

Microfluidic cell culture systems for drug research

(2010) Min-Hsien Wu et al.   LAB ON A CHIP

A rapid and simple fabrication method for 3-dimensional circular microfluidic channel using metal wire removal process

(2010) Suk-Heung Song et al.   Microfluidics and Nanofluidics

Bacterial Chemotaxis in Linear and Nonlinear Steady Microfluidic Gradients

(2010) Tanvir Ahmed et al.   NANO LETTERS

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Hierarchically Designed Agarose and Poly(Ethylene Glycol) Interpenetrating Network Hydrogels for Cartilage Tissue Engineering

(2010) Brandon J. DeKosky et al.   TISSUE ENGINEERING PART C-METHODS

Hydrogels in Regenerative Medicine

(2009) Brandon V. Slaughter et al.   ADVANCED MATERIALS

Bio-microfluidics: Biomaterials and Biomimetic Designs

(2009) Peter Domachuk et al.   ADVANCED MATERIALS

Human microvasculature fabrication using thermal inkjet printing technology

(2009) Xiaofeng Cui et al.   BIOMATERIALS

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

On-demand three-dimensional freeform fabrication of multi-layered hydrogel scaffold with fluidic channels

(2009) Wonhye Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Thermal behavior and mechanical properties of physically crosslinked PVA/Gelatin hydrogels

(2009) Yurong Liu et al.   Journal of the Mechanical Behavior of Biomedical Materials

Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments

(2009) Chi Zhang et al.   LAB ON A CHIP

Biological implications of polydimethylsiloxane-based microfluidic cell culture

(2009) Keil J. Regehr et al.   LAB ON A CHIP

Visualizing the 3D Internal Structure of Calcite Single Crystals Grown in Agarose Hydrogels

(2009) H. Li et al.   SCIENCE

Fabrication of an artificial 3-dimensional vascular network using sacrificial sugar structures

(2009) Leon M. Bellan et al.   Soft Matter

Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration

(2008) Soo-Hong Lee et al.   BIOMATERIALS

Effect of hydrogel porosity on marrow stromal cell phenotypic expression

(2008) Mahrokh Dadsetan et al.   BIOMATERIALS

Integration column: Microfluidic high-throughput screening

(2008) Sebastian J. Maerkl   Integrative Biology

Smart Hydrogels Containing Adenylate Kinase: Translating Substrate Recognition into Macroscopic Motion

(2008) Weiwei Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modular microfluidics for gradient generation

(2008) Kang Sun et al.   LAB ON A CHIP

Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging

(2008) Vernella Vickerman et al.   LAB ON A CHIP

Microfluidic-based synthesis of non-spherical magnetic hydrogel microparticles

(2008) Dae Kun Hwang et al.   LAB ON A CHIP

A Novel Double-Network Hydrogel Induces Spontaneous Articular Cartilage Regenerationin vivoin a Large Osteochondral Defect

(2008) Kazunori Yasuda et al.   MACROMOLECULAR BIOSCIENCE

Influence of decreasing nutrient path length on the development of engineered cartilage

(2008) L. Bian et al.   OSTEOARTHRITIS AND CARTILAGE

Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs

(2008) Y. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered Microenvironments for Controlled Stem Cell Differentiation

(2008) Jason A. Burdick et al.   TISSUE ENGINEERING PART A

Mechanically Robust and Bioadhesive Collagen and Photocrosslinkable Hyaluronic Acid Semi-Interpenetrating Networks

(2008) Mark D. Brigham et al.   TISSUE ENGINEERING PART A

Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications

(2008) Garret D. Nicodemus et al.   TISSUE ENGINEERING PART B-REVIEWS