Cooperative Roles of SDF-1α and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

Quantitative analysis of gradient sensing: towards building predictive models of chemotaxis in cancer

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Hallmarks of Cancer: The Next Generation

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Receptor differential activation and cooperativity better explain cellular preference for different chemoattractant gradient shapes in an EGFR system

(2011) Joshua B. White et al.   Integrative Biology

Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber

(2011) Ulrike Haessler et al.   Integrative Biology

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

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Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro

(2010) Valerie L. Cross et al.   BIOMATERIALS

CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression

(2010) Xueqing Sun et al.   CANCER AND METASTASIS REVIEWS

A new chemotaxis device for cell migration studies

(2010) Waseem Khan Raja et al.   Integrative Biology

Biological applications of microfluidic gradient devices

(2010) Sudong Kim et al.   Integrative Biology

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

An agarose-based microfluidic platform with a gradient buffer for 3D chemotaxis studies

(2009) Ulrike Haessler et al.   BIOMEDICAL MICRODEVICES

Screening of a PKC ζ-specific kinase inhibitor PKCzI257.3 which inhibits EGF-induced breast cancer cell chemotaxis

(2009) Jing Wu et al.   INVESTIGATIONAL NEW DRUGS

Epidermal growth factor promotes breast cancer cell chemotaxis in CXCL12 gradients

(2008) Bobak Mosadegh et al.   BIOTECHNOLOGY AND BIOENGINEERING

Small Neutralizing Molecules to Inhibit Actions of the Chemokine CXCL12

(2008) Muriel Hachet-Haas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial cell polarization and chemotaxis in a microfluidic device

(2008) Amir Shamloo et al.   LAB ON A CHIP

A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment

(2008) Vinay V. Abhyankar et al.   LAB ON A CHIP

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE