Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19
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Title
Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19
Authors
Keywords
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Journal
MOLECULES
Volume 25, Issue 19, Pages 4410
Publisher
MDPI AG
Online
2020-09-25
DOI
10.3390/molecules25194410
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Note: Only part of the references are listed.- DNA Sensing in the Innate Immune Response
- (2020) Benoit Briard et al. PHYSIOLOGY
- Melatonin Inhibits Formation of Mitochondrial Permeability Transition Pores and Improves Oxidative Phosphorylation of Frozen-Thawed Ram Sperm
- (2020) Yi Fang et al. Frontiers in Endocrinology
- Melatonin improves mitochondrial biogenesis through the AMPK/PGC1α pathway to attenuate ischemia/reperfusion-induced myocardial damage
- (2020) Xueyan Qi et al. Aging-US
- Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection
- (2020) Livan Delgado-Roche et al. ARCHIVES OF MEDICAL RESEARCH
- Thromboembolic risk and anticoagulant therapy in COVID‐19 patients: emerging evidence and call for action
- (2020) Anastasios Kollias et al. BRITISH JOURNAL OF HAEMATOLOGY
- The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China
- (2020) Wen Zhang et al. CLINICAL IMMUNOLOGY
- Can melatonin reduce the severity of COVID-19 pandemic?
- (2020) Alex Shneider et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Virtual Screening-Driven Drug Discovery of SARS-CoV2 Enzyme Inhibitors Targeting Viral Attachment, Replication, Post-Translational Modification and Host Immunity Evasion Infection Mechanisms
- (2020) Mark Tristan J. Quimque et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Melatonin modulates mitophagy, innate immunity and circadian clocks in a model of viral‐induced fulminant hepatic failure
- (2020) Irene Crespo et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration
- (2020) Abhishek Jauhari et al. JOURNAL OF CLINICAL INVESTIGATION
- Anticoagulant and antiarrhythmic effects of heparin in the treatment of COVID‐19 patients
- (2020) Francisco Sandro Menezes‐Rodrigues et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum
- (2020) Geoffrey D. Barnes et al. JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- Sex Differences in COVID-19 Case Fatality Rate: Insights From a Multinational Registry
- (2020) Mohamad Alkhouli et al. MAYO CLINIC PROCEEDINGS
- Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients
- (2020) T. Klopfenstein et al. MEDECINE ET MALADIES INFECTIEUSES
- Melatonin Attenuates Calcium Deposition from Vascular Smooth Muscle Cells by Activating Mitochondrial Fusion and Mitophagy via an AMPK/OPA1 Signaling Pathway
- (2020) Wei Ren Chen et al. Oxidative Medicine and Cellular Longevity
- Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation
- (2020) Mindi He et al. Oxidative Medicine and Cellular Longevity
- Effective treatment of severe COVID-19 patients with tocilizumab
- (2020) Xiaoling Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Melatonin: Roles in influenza, Covid‐19, and other viral infections
- (2020) George Anderson et al. REVIEWS IN MEDICAL VIROLOGY
- Melatonin Attenuates Anoxia/Reoxygenation Injury by Inhibiting Excessive Mitophagy Through the MT2/SIRT3/FoxO3a Signaling Pathway in H9c2 Cells
- (2020) Jinjing Wu et al. Drug Design Development and Therapy
- BNIP3L-Dependent Mitophagy Promotes HBx-Induced Cancer Stemness of Hepatocellular Carcinoma Cells via Glycolysis Metabolism Reprogramming
- (2020) Yuan-Yuan Chen et al. Cancers
- Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
- (2020) Yadi Zhou et al. Cell Discovery
- On Determining the Age Distribution of COVID-19 Pandemic
- (2020) Dominic Cortis Frontiers in Public Health
- Clinical Course and Factors Associated with Hospitalization and Critical Illness Among COVID‐19 Patients in Chicago, Illinois
- (2020) Michael Gottlieb et al. ACADEMIC EMERGENCY MEDICINE
- Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis
- (2020) Keshav K. Singh et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The World Goes Bats: Living Longer and Tolerating Viruses
- (2020) Vera Gorbunova et al. Cell Metabolism
- Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis
- (2020) Ana Campos Codo et al. Cell Metabolism
- Coronavirus Disease 2019 (COVID-19) and Its Neuroinvasive Capacity: Is It Time for Melatonin?
- (2020) Alejandro Romero et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Biomarkers of Platelet Activity and Vascular Health Associate with Thrombosis and Mortality in Patients with COVID-19
- (2020) Tessa J Barrett et al. CIRCULATION RESEARCH
- COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach
- (2020) Feixiong Cheng et al. CLEVELAND CLINIC JOURNAL OF MEDICINE
- Characteristics and predictors of death among 4,035 consecutively hospitalized patients with COVID-19 in Spain
- (2020) Juan Berenguer et al. CLINICAL MICROBIOLOGY AND INFECTION
- Convalescent plasma treatment for SARS-CoV-2 infection: analysis of the first 436 donors in England, 22 April to 12 May 2020
- (2020) Heli Harvala et al. Eurosurveillance
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- (2020) Bo Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
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- (2020) Alessandro Capone INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
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- (2020) Russel J. Reiter et al. JOURNAL OF PINEAL RESEARCH
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- Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment
- (2020) Virna Margarita Martín Giménez et al. LIFE SCIENCES
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- (2020) Russel J. Reiter et al. Frontiers in Medicine
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- (2020) Anastasia V. Poznyak et al. Biomedicines
- Pediatric COVID-19: Systematic review of the literature
- (2020) Neha A. Patel AMERICAN JOURNAL OF OTOLARYNGOLOGY
- Melatonin is a potential adjuvant to improve clinical outcomes in individuals with obesity and diabetes with coexistence of Covid-19
- (2020) Mohamed A. El-Missiry et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Role of comorbidities like diabetes on severe acute respiratory syndrome coronavirus-2: A review
- (2020) Subham Das et al. LIFE SCIENCES
- The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach
- (2020) Gerwyn Morris et al. LIFE SCIENCES
- Is melatonin deficiency a unifying pathomechanism of high risk patients with COVID-19?
- (2020) Fedor Simko et al. LIFE SCIENCES
- Matrix metallopeptidase 9 as a host protein target of chloroquine and melatonin for immunoregulation in COVID-19: A network-based meta-analysis
- (2020) Suvojit Hazra et al. LIFE SCIENCES
- Mitochondria and microbiota dysfunction in COVID-19 pathogenesis
- (2020) Jumana Saleh et al. MITOCHONDRION
- Long-term oral melatonin alleviates memory deficits, reduces amyloid-β deposition associated with downregulation of BACE1 and mitophagy in APP/PS1 transgenic mice
- (2020) Cuimei Sun et al. NEUROSCIENCE LETTERS
- Clinical Trials for Use of Melatonin to Fight against COVID-19 Are Urgently Needed
- (2020) Konrad Kleszczyński et al. Nutrients
- The effect of different wavelengths of light during incubation on the development of rhythmic pineal melatonin biosynthesis in chick embryos
- (2019) A. Drozdova et al. Animal
- Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition
- (2019) Yu Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy
- (2019) Alagie Jassey et al. Cells
- Hemin-induced platelet activation and ferroptosis is mediated through ROS-driven proteasomal activity and inflammasome activation: Protection by Melatonin
- (2019) Somanathapura K. NaveenKumar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Aging: An evolutionary competition between host cells and mitochondria
- (2019) Dun-Xian Tan MEDICAL HYPOTHESES
- Mitochondria in the biology, pathogenesis, and treatment of hepatitis virus infections
- (2019) Changbo Qu et al. REVIEWS IN MEDICAL VIROLOGY
- Melatonin: Clinical Perspectives in Neurodegeneration
- (2019) Daniel P. Cardinali Frontiers in Endocrinology
- Melatonin and Parkinson Disease: Current Status and Future Perspectives for Molecular Mechanisms
- (2019) Omid Reza Tamtaji et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Melatonin Enhances Mitophagy by Upregulating Expression of Heat Shock 70 kDa Protein 1L in Human Mesenchymal Stem Cells under Oxidative Stress
- (2019) Yeo Min Yoon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mink Enteritis Virus Infection Induces Mitochondrion-mediated Apoptosis by the Viral Nonstructural Protein 1
- (2019) Peng Lin et al. JOURNAL OF VIROLOGY
- Mitochondria—Striking a balance between host and endosymbiont
- (2019) Richard J. Youle SCIENCE
- Mitochondria as central hub of the immune system
- (2019) Cristiane Naffah de Souza Breda et al. Redox Biology
- The Effects of Melatonin Supplementation on Parameters of Mental Health, Glycemic Control, Markers of Cardiometabolic Risk, and Oxidative Stress in Diabetic Hemodialysis Patients: A Randomized, Double-Blind, Placebo-Controlled Trial
- (2019) Vahidreza Ostadmohammadi et al. JOURNAL OF RENAL NUTRITION
- Glutaminolysis and glycolysis are essential for optimal replication of Marek's disease virus
- (2019) Nitish Boodhoo et al. JOURNAL OF VIROLOGY
- Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation
- (2019) Lili Liu et al. LIFE SCIENCES
- Sex-specific effects of mitochondrial haplotype on metabolic rate in Drosophila melanogaster support predictions of the Mother's Curse hypothesis
- (2019) Venkatesh Nagarajan-Radha et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats
- (2019) Hester Rijkje Berger et al. PLoS One
- The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity
- (2018) Stephanie S. Pavlovich et al. CELL
- Serum melatonin levels are associated with mortality in patients with malignant middle cerebral artery infarction
- (2018) Leonardo Lorente et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Melatonin increases brown adipose tissue mass and function in Zücker diabetic fatty rats: implications for obesity control
- (2018) Gumersindo Fernández Vázquez et al. JOURNAL OF PINEAL RESEARCH
- Infection with phytopathogenic bacterium inhibits melatonin biosynthesis, decreases longevity of its vector, and suppresses the free radical-defense
- (2018) Yasser Nehela et al. JOURNAL OF PINEAL RESEARCH
- Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury
- (2018) Hao Zhou et al. JOURNAL OF PINEAL RESEARCH
- Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland
- (2018) Dun Tan et al. MOLECULES
- Choroid plexus is an additional source of melatonin in the brain
- (2018) Telma Quintela et al. JOURNAL OF PINEAL RESEARCH
- Structural basis of mitochondrial receptor binding and constriction by DRP1
- (2018) Raghav Kalia et al. NATURE
- Mitochondria in innate immune signaling
- (2018) Balaji Banoth et al. Translational Research
- Treating Influenza Infection, From Now and Into the Future
- (2018) Sophia Davidson Frontiers in Immunology
- Aanat Knockdown and Melatonin Supplementation in Embryo Development: Involvement of Mitochondrial Function and DNA Methylation
- (2018) Minghui Yang et al. ANTIOXIDANTS & REDOX SIGNALING
- The Effects of Melatonin Supplementation on Glycemic Control: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- (2018) Amin Doosti-Irani et al. HORMONE AND METABOLIC RESEARCH
- Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells
- (2018) Konrad Kleszczyński et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Plant mitochondria synthesize melatonin and enhance the tolerance of plants to drought stress
- (2017) Lin Wang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission-VDAC1-HK2-mPTP-mitophagy axis
- (2017) Hao Zhou et al. JOURNAL OF PINEAL RESEARCH
- Melatonin suppresses platelet activation and function against cardiac ischemia/reperfusion injury via PPARγ/FUNDC1/mitophagy pathways
- (2017) Hao Zhou et al. JOURNAL OF PINEAL RESEARCH
- Melatonin Improves the Quality of Inferior Bovine Oocytes and Promoted Their Subsequent IVF Embryo Development: Mechanisms and Results
- (2017) Minghui Yang et al. MOLECULES
- Mitochondrial diseases: the contribution of organelle stress responses to pathology
- (2017) Anu Suomalainen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet
- (2017) Karolina Szewczyk-Golec et al. Oxidative Medicine and Cellular Longevity
- Mitophagy and age-related pathologies: Development of new therapeutics by targeting mitochondrial turnover
- (2017) Konstantinos Palikaras et al. PHARMACOLOGY & THERAPEUTICS
- Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases
- (2017) Ana López et al. PLoS One
- Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
- (2017) Yalikun Suofu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2017) Marta Martinez-Vicente Frontiers in Molecular Neuroscience
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- (2017) Zorica Janjetovic et al. Scientific Reports
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- (2017) Takuma Yoshizumi et al. Scientific Reports
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- (2016) Evanna L. Mills et al. CELL
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- (2016) Tiinamaija Tuomi et al. Cell Metabolism
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- (2016) Jie Zan et al. EXPERIMENTAL CELL RESEARCH
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- (2016) Dun-Xian Tan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2013) Shankar S. Iyer et al. IMMUNITY
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- Inflamm-ageing
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- (2012) Kenichi Shimada et al. IMMUNITY
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- (2012) Dun-Xian Tan et al. JOURNAL OF PINEAL RESEARCH
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- (2011) Tiffany T. Nguyen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Bjarne Østerud THROMBOSIS RESEARCH
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- (2011) Yongjun Yu et al. TRENDS IN MICROBIOLOGY
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- (2010) Elmar Peschke et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2010) Marcel Levi et al. CRITICAL CARE MEDICINE
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- (2010) D.-X. Tan et al. Obesity Reviews
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- (2008) Dave Lanoix et al. JOURNAL OF PINEAL RESEARCH
- Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
- (2008) Valeriya Lyssenko et al. NATURE GENETICS
- Association of ischemia-modified albumin and melatonin in patients with ST-elevation myocardial infarction
- (2007) Alberto Dominguez-Rodriguez et al. ATHEROSCLEROSIS
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