Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy

Reactive Oxygen Species-Mediated c-Jun NH 2 -Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction

(2017) Linmao Zhong et al.   JOURNAL OF VIROLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Global epidemiology and burden of HCV infection and HCV-related disease

(2016) Aaron P. Thrift et al.   Nature Reviews Gastroenterology & Hepatology

Hepatitis C Virus NS5A Protein Triggers Oxidative Stress by Inducing NADPH Oxidases 1 and 4 and Cytochrome P450 2E1

(2016) Olga A. Smirnova et al.   Oxidative Medicine and Cellular Longevity

Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation

(2016) Gavin Ka Yu Siu et al.   Scientific Reports

Hepatitis C virus and autophagy

(2015) Linya Wang et al.   BIOLOGICAL CHEMISTRY

RIG-I in RNA virus recognition

(2015) Alison M. Kell et al.   VIROLOGY

HCV Induces the Expression of Rubicon and UVRAG to Temporally Regulate the Maturation of Autophagosomes and Viral Replication

(2015) Linya Wang et al.   PLoS Pathogens

Hepatitis C Virus Core Protein Suppresses Mitophagy by Interacting with Parkin in the Context of Mitochondrial Depolarization

(2014) Yuichi Hara et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of core expression during the hepatitis C virus life cycle

(2014) M. S. Afzal et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis C virus NS5A drives a PTEN-PI3K/Akt feedback loop to support cell survival

(2014) Du Cheng et al.   LIVER INTERNATIONAL

Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence

(2014) S.-J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection

(2013) Ralf Bartenschlager et al.   NATURE REVIEWS MICROBIOLOGY

Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy

(2013) Seong-Jun Kim et al.   PLoS Pathogens

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy

(2012) He Huang et al.   Autophagy

Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin

(2012) Michael Lazarou et al.   DEVELOPMENTAL CELL

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

(2012) Andrew W Greene et al.   EMBO REPORTS

PINK1- and Parkin-mediated mitophagy at a glance

(2012) Seok Min Jin et al.   JOURNAL OF CELL SCIENCE

p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45  expression via the NF- B and PI3K-Akt pathways

(2012) D. Cheng et al.   JOURNAL OF GENERAL VIROLOGY

Transient Structure and SH3 Interaction Sites in an Intrinsically Disordered Fragment of the Hepatitis C Virus Protein NS5A

(2012) Sophie Feuerstein et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling

(2011) T. Koshiba et al.   Science Signaling

The Interplay Between Mitochondrial Dynamics and Mitophagy

(2010) Gilad Twig et al.   ANTIOXIDANTS & REDOX SIGNALING

Under the ROS: Thiol network is the principal suspect for autophagy commitment

(2010) Giuseppe Filomeni et al.   Autophagy

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

(2010) Po-Yuan Ke et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection

(2010) Carl Guévin et al.   VIROLOGY

Knockdown of autophagy-related gene decreases the production of infectious Hepatitis C virus particles

(2009) Isei Tanida et al.   Autophagy

Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway

(2009) Céline Castanier et al.   EMBO REPORTS

Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1 -Mediated Glycolytic Adaptation

(2009) M. Ripoli et al.   JOURNAL OF VIROLOGY

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

(2008) Donna Sir et al.   HEPATOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles

(2008) T. Masaki et al.   JOURNAL OF VIROLOGY