Connections between Metabolism and Epigenetic Modification in MDSCs
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Connections between Metabolism and Epigenetic Modification in MDSCs
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 19, Pages 7356
Publisher
MDPI AG
Online
2020-10-05
DOI
10.3390/ijms21197356
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metabolic changes and interaction of tumor cell, myeloid-derived suppressor cell and T cell in hypoxic microenvironment
- (2020) Xiantu Ou et al. Future Oncology
- Anti‐inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor‐bearing mice
- (2020) Yali Tuo et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer
- (2020) Varun Sasidharan Nair et al. Clinical Epigenetics
- Targeted deletion of PD-1 in myeloid cells induces antitumor immunity
- (2020) Laura Strauss et al. Science Immunology
- DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR– myeloid cells, compared with HLA-DR+ antigen-presenting cells
- (2020) Reem Saleh et al. Epigenetics
- Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
- (2020) Tobias Baumann et al. NATURE IMMUNOLOGY
- Metabolic Modulation of the Tumor Microenvironment Leads to Multiple Checkpoint Inhibition and Immune Cell Infiltration
- (2020) David Kolb et al. ACS Nano
- Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells
- (2020) Alyssa D. Smith et al. CANCER RESEARCH
- Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer
- (2020) Yonatan Katzenelenbogen et al. CELL
- Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells
- (2020) Min-Hee Oh et al. JOURNAL OF CLINICAL INVESTIGATION
- Enzalutamide, an Androgen Receptor Antagonist, Enhances Myeloid Cell–Mediated Immune Suppression and Tumor Progression
- (2020) Camila R. Consiglio et al. Cancer Immunology Research
- Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance
- (2020) Nuray Erin et al. DRUG RESISTANCE UPDATES
- AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging
- (2019) Antero Salminen et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer
- (2019) Shweta Joshi et al. MOLECULAR CANCER THERAPEUTICS
- Fatty acid transport protein 2 reprograms neutrophils in cancer
- (2019) Filippo Veglia et al. NATURE
- Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation
- (2019) Denise E. de Almeida Nagata et al. Cell Reports
- Macrophages and Metabolism in the Tumor Microenvironment
- (2019) Ilio Vitale et al. Cell Metabolism
- Connections between metabolism and epigenetics in cancers
- (2019) Chitra Thakur et al. SEMINARS IN CANCER BIOLOGY
- Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor
- (2019) Dehong Yan et al. Frontiers in Immunology
- Survival of the fittest: how myeloid-derived suppressor cells survive in the inhospitable tumor microenvironment
- (2019) Suzanne Ostrand-Rosenberg et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells
- (2019) Jimena Trillo-Tinoco et al. CANCER RESEARCH
- Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses
- (2019) Xi Chen et al. Acta Pharmaceutica Sinica B
- Metabolic regulation of gene expression by histone lactylation
- (2019) Di Zhang et al. NATURE
- Metformin inhibits the function of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
- (2019) Peiqi Xu et al. BIOMEDICINE & PHARMACOTHERAPY
- Energy metabolism manipulates the fate and function of tumour myeloid-derived suppressor cells
- (2019) Cong Hu et al. BRITISH JOURNAL OF CANCER
- Targeting aerobic glycolysis by dichloroacetate improves Newcastle disease virus-mediated viro-immunotherapy in hepatocellular carcinoma
- (2019) Gang Meng et al. BRITISH JOURNAL OF CANCER
- Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence
- (2018) Antero Salminen et al. BIOGERONTOLOGY
- mTOR-mediated glycolysis contributes to the enhanced suppressive function of murine tumor-infiltrating monocytic myeloid-derived suppressor cells
- (2018) Yuting Deng et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- SIRT1 and HIF1α signaling in metabolism and immune responses
- (2018) Qing Yu et al. CANCER LETTERS
- Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer
- (2018) Lifeng Li et al. CANCER RESEARCH
- Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer
- (2018) Wei Li et al. Cell Metabolism
- IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma
- (2018) Erik Ladomersky et al. CLINICAL CANCER RESEARCH
- Plasticity of myeloid-derived suppressor cells in cancer
- (2018) Evgenii Tcyganov et al. CURRENT OPINION IN IMMUNOLOGY
- Protein-Based Inheritance: Epigenetics beyond the Chromosome
- (2018) Zachary H. Harvey et al. MOLECULAR CELL
- Analysis of DNA methylation in cancer: location revisited
- (2018) Alexander Koch et al. Nature Reviews Clinical Oncology
- Histone deacetylase 6 regulates the immunosuppressive properties of cancer-associated fibroblasts in breast cancer through the STAT3–COX2-dependent pathway
- (2018) Ang Li et al. ONCOGENE
- LXR Agonism Depletes MDSCs to Promote Antitumor Immunity
- (2018) Cancer Discovery
- Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis
- (2018) Guohui Qin et al. OncoImmunology
- The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process
- (2018) Antero Salminen et al. AGEING RESEARCH REVIEWS
- Corrigendum to “Readers of DNA methylation, the MBD family as potential therapeutic targets” [Pharmacology & Therapeutics 184 (1) (2018) 98-111]
- (2018) Gordon D. Ginder et al. PHARMACOLOGY & THERAPEUTICS
- Metformin induces CD11b+-cell-mediated growth inhibition of an osteosarcoma: implications for metabolic reprogramming of myeloid cells and anti-tumor effects
- (2018) Takenori Uehara et al. INTERNATIONAL IMMUNOLOGY
- Reciprocal Regulation of AMPK/SNF1 and Protein Acetylation
- (2018) Ales Vancura et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma
- (2018) Veronica Huber et al. JOURNAL OF CLINICAL INVESTIGATION
- MDSC; the Most Important Cell You Have Never Heard Of
- (2018) R.J. Tesi TRENDS IN PHARMACOLOGICAL SCIENCES
- Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
- (2018) Kim De Veirman et al. CANCER LETTERS
- AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1
- (2017) Traci L. Marin et al. Science Signaling
- Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immunomodulation
- (2017) Veronica Huber et al. SEMINARS IN CANCER BIOLOGY
- Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis
- (2017) Shiou-Ling Jian et al. Cell Death & Disease
- Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
- (2017) David Kung-Chun Chiu et al. Nature Communications
- Prostaglandin E2 Leads to the Acquisition of DNMT3A-Dependent Tolerogenic Functions in Human Myeloid-Derived Suppressor Cells
- (2017) Javier Rodríguez-Ubreva et al. Cell Reports
- AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1
- (2017) Traci L. Marin et al. Science Signaling
- Myeloid-Derived Suppressor Cells
- (2017) Dmitry I. Gabrilovich Cancer Immunology Research
- Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells
- (2017) Amir A. Al-Khami et al. OncoImmunology
- A Dynamic Metabolic Flux Analysis of Myeloid-Derived Suppressor Cells Confirms Immunosuppression-Related Metabolic Plasticity
- (2017) Guillaume Goffaux et al. Scientific Reports
- mTOR signaling disruption from myeloid-derived suppressive cells protects against immune-mediated hepatic injury through the HIF1α-dependent glycolytic pathway
- (2016) Xi Chen et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Understanding the epigenetic regulation of tumours and their microenvironments: opportunities and problems for epigenetic therapy
- (2016) Man Liu et al. JOURNAL OF PATHOLOGY
- The ever-expanding role of HIF in tumour and stromal biology
- (2016) Edward L. LaGory et al. NATURE CELL BIOLOGY
- The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
- (2016) Vinit Kumar et al. TRENDS IN IMMUNOLOGY
- Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
- (2016) Vincenzo Bronte et al. Nature Communications
- Epigenetics in myeloid derived suppressor cells: a sheathed sword towards cancer
- (2016) Chao Zhang et al. Oncotarget
- Metabolic reprogramming of myeloid-derived suppressor cells (MDSC) in cancer
- (2016) Amir A. Al-Khami et al. OncoImmunology
- mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors
- (2016) Tingting Wu et al. Scientific Reports
- DNA Methylation, Its Mediators and Genome Integrity
- (2015) Huan Meng et al. International Journal of Biological Sciences
- Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function
- (2015) Eva Sahakian et al. MOLECULAR IMMUNOLOGY
- Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner
- (2015) Rikke B. Holmgaard et al. Cell Reports
- Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
- (2015) F. Hossain et al. Cancer Immunology Research
- AMPK—Sensing Energy while Talking to Other Signaling Pathways
- (2014) D. Grahame Hardie Cell Metabolism
- Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice
- (2014) J.-I. Youn et al. JOURNAL OF IMMUNOLOGY
- Cross Talk between Histone Deacetylase 4 and STAT6 in the Transcriptional Regulation of Arginase 1 during Mouse Dendritic Cell Differentiation
- (2014) Quan Yang et al. MOLECULAR AND CELLULAR BIOLOGY
- mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity
- (2014) S.-C. Cheng et al. SCIENCE
- The Tumor Microenvironment Shapes Lineage, Transcriptional, and Functional Diversity of Infiltrating Myeloid Cells
- (2014) K. G. Elpek et al. Cancer Immunology Research
- SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1 -Dependent Glycolysis
- (2013) G. Liu et al. CANCER RESEARCH
- Influence of Metabolism on Epigenetics and Disease
- (2013) William G. Kaelin et al. CELL
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
- (2013) Z. Husain et al. JOURNAL OF IMMUNOLOGY
- Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
- (2013) Christian C. Dibble et al. NATURE CELL BIOLOGY
- Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer
- (2013) Je-In Youn et al. NATURE IMMUNOLOGY
- Tumor-derived lactate and myeloid-derived suppressor cells: Linking metabolism to cancer immunology
- (2013) Zaheed Husain et al. OncoImmunology
- l-glutamine is a key parameter in the immunosuppression phenomenon
- (2012) Ines Hammami et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models
- (2012) Ines Hammami et al. BMC CELL BIOLOGY
- Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes
- (2012) A. Calcinotto et al. CANCER RESEARCH
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- Functions of DNA methylation: islands, start sites, gene bodies and beyond
- (2012) Peter A. Jones NATURE REVIEWS GENETICS
- DNA Methylation and Its Basic Function
- (2012) Lisa D Moore et al. NEUROPSYCHOPHARMACOLOGY
- Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression
- (2012) Tom Latham et al. NUCLEIC ACIDS RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo
- (2011) Brian R. Rosborough et al. JOURNAL OF LEUKOCYTE BIOLOGY
- HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
- (2010) Cesar A. Corzo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
- (2010) J. D. Mezrich et al. JOURNAL OF IMMUNOLOGY
- IL4Rα + Myeloid-Derived Suppressor Cell Expansion in Cancer Patients
- (2009) Susanna Mandruzzato et al. JOURNAL OF IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started