DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR– myeloid cells, compared with HLA-DR+ antigen-presenting cells

Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer

(2020) Varun Sasidharan Nair et al.   Clinical Epigenetics

Tim-3/galectin-9 pathway and mMDSC control primary and secondary resistances to PD-1 blockade in lung cancer patients

(2019) Emeric Limagne et al.   OncoImmunology

Hypoxia-induced VISTA promotes the suppressive function of myeloid- derived suppressor cells in the tumor microenvironment

(2019) Jie Deng et al.   Cancer Immunology Research

Disorder of Coagulation-Fibrinolysis System: An Emerging Toxicity of Anti-PD-1/PD-L1 Monoclonal Antibodies

(2019) Ryo Sato et al.   Journal of Clinical Medicine

Correlation between MDSC and Immune Tolerance in Transplantation: Cytokines, Pathways and Cell-cell Interaction

(2019) Tianying Yang et al.   CURRENT GENE THERAPY

Acquired resistance to cancer immunotherapy: Role of tumor-mediated immunosuppression

(2019) Reem Saleh et al.   SEMINARS IN CANCER BIOLOGY

Matrix Metalloproteinase-9 in Monocytic Myeloid-Derived Suppressor Cells Correlate with Early Infections and Clinical Outcomes in Allogeneic Hematopoietic Stem Cell Transplantation

(2018) Sung-Eun Lee et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy

(2018) David A. Bernal-Estévez et al.   BMC CANCER

Regulation and Function of the PD-L1 Checkpoint

(2018) Chong Sun et al.   IMMUNITY

Therapeutic prospects of targeting myeloid-derived suppressor cells and immune checkpoints in cancer

(2018) Salman M Toor et al.   IMMUNOLOGY AND CELL BIOLOGY

DNMT1 regulates expression of MHC class I in post-mitotic neurons

(2018) Julie Ry Gustafsson et al.   Molecular Brain

DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer

(2018) Varun Sasidharan Nair et al.   Clinical Epigenetics

Myeloid-Derived Suppressor Cells Hinder the Anti-Cancer Activity of Immune Checkpoint Inhibitors

(2018) Rebekka Weber et al.   Frontiers in Immunology

Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression

(2018) Viktor Fleming et al.   Frontiers in Immunology

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

(2018) Liru Wang et al.   OncoImmunology

Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression

(2018) Robin Maximilian Awad et al.   Frontiers in Immunology

Autocrine TGFβ is a Survival Factor for Monocytes and Drives Immunosuppressive Lineage Commitment

(2018) Alba Gonzalez-Junca et al.   Cancer Immunology Research

Roles of Myeloid-Derived Suppressor Cell Subpopulations in Autoimmune Arthritis

(2018) Min Li et al.   Frontiers in Immunology

The Yin and Yang of Myeloid Derived Suppressor Cells

(2018) Snehil Budhwar et al.   Frontiers in Immunology

DNA methylation of immune checkpoints in the peripheral blood of breast and colorectal cancer patients

(2018) Asma A. Elashi et al.   OncoImmunology

Tim-3 and its role in regulating anti-tumor immunity

(2017) Madhumita Das et al.   IMMUNOLOGICAL REVIEWS

Myeloid-derived suppressor cells mediate tolerance induction in autoimmune disease

(2017) Anja Wegner et al.   IMMUNOLOGY

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

(2017) Jianjun Gao et al.   NATURE MEDICINE

The Role of Myeloid-Derived Suppressor Cells in Viral Infection

(2017) Megan A. O'Connor et al.   VIRAL IMMUNOLOGY

Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection

(2017) Shomyseh Sanjabi et al.   Cold Spring Harbor Perspectives in Biology

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells

(2017) Isabel Gonçalves Silva et al.   EBioMedicine

DNA methylation perspectives in the pathogenesis of autoimmune diseases

(2016) Bao Sun et al.   CLINICAL IMMUNOLOGY

Epigenetic modifiers in immunotherapy: a focus on checkpoint inhibitors

(2016) Manuela Terranova-Barberio et al.   Immunotherapy

DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases

(2016) Varun Sasidharan Nair et al.   MOLECULES AND CELLS

Epigenetics in myeloid derived suppressor cells: a sheathed sword towards cancer

(2016) Chao Zhang et al.   Oncotarget

Myeloid-Derived Suppressor Cells Are Controlled by Regulatory T Cells via TGF-β during Murine Colitis

(2016) Cho-Rong Lee et al.   Cell Reports

MDSC and TGF  Are Required for Facilitation of Tumor Growth in the Lungs of Mice Exposed to Carbon Nanotubes

(2015) A. A. Shvedova et al.   CANCER RESEARCH

DNA demethylating agent 5-azacytidine inhibits myeloid-derived suppressor cells induced by tumor growth and cyclophosphamide treatment

(2014) Romana Mikyšková et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Connections between TET proteins and aberrant DNA modification in cancer

(2014) Yun Huang et al.   TRENDS IN GENETICS

Epigenetic modulation of the immune function

(2013) Beatriz Suárez-Álvarez et al.   Epigenetics

Myeloid-derived suppressor cells in cancer: recent progress and prospects

(2013) Yazan S Khaled et al.   IMMUNOLOGY AND CELL BIOLOGY

The critical importance of epigenetics in autoimmunity

(2013) Qianjin Lu   JOURNAL OF AUTOIMMUNITY

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

(2013) William A. Pastor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

Basic concepts of epigenetics

(2012) Elizabeth A. Mazzio et al.   Epigenetics

The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

(2012) Dennis Lindau et al.   IMMUNOLOGY

Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth

(2012) E. Schlecker et al.   JOURNAL OF IMMUNOLOGY

MDSC in autoimmunity

(2011) James G. Cripps et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses

(2011) Li Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tim-3/Galectin-9 Pathway: Regulation of Th1 Immunity through Promotion of CD11b+Ly-6G+ Myeloid Cells

(2010) V. Dardalhon et al.   JOURNAL OF IMMUNOLOGY

Epigenetic mechanisms and genome stability

(2010) Emily L. Putiri et al.   Clinical Epigenetics

Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands

(2009) Angela Meier et al.   AIDS

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS