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Title
The SUMO pathway in pancreatic cancer: insights and inhibition
Authors
Keywords
-
Journal
BRITISH JOURNAL OF CANCER
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-10-19
DOI
10.1038/s41416-020-01119-6
References
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Related references
Note: Only part of the references are listed.- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- SUMO pathway inhibition targets an aggressive pancreatic cancer subtype
- (2020) Alexander Biederstädt et al. GUT
- Randomized, Multicenter, Phase II Trial of Gemcitabine and Cisplatin With or Without Veliparib in Patients With Pancreas Adenocarcinoma and a Germline BRCA/PALB2 Mutation
- (2020) Eileen M. O’Reilly et al. JOURNAL OF CLINICAL ONCOLOGY
- Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution
- (2020) Michelle Chan-Seng-Yue et al. NATURE GENETICS
- Cellular adaptation to hypoxia through hypoxia inducible factors and beyond
- (2020) Pearl Lee et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Myc instructs and maintains pancreatic adenocarcinoma phenotype
- (2020) Nicole M Sodir et al. Cancer Discovery
- Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection
- (2020) Wungki Park et al. CLINICAL CANCER RESEARCH
- HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer
- (2020) Mark Kalisz et al. EMBO JOURNAL
- Blocking the road to de‐differentiation: HNF 1A/ KDM 6A complex safeguards epithelial integrity in pancreatic cancer
- (2020) Stefanie Bärthel et al. EMBO JOURNAL
- Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma
- (2020) Nathiya Muthalagu et al. Cancer Discovery
- MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities
- (2020) Julia Rohrberg et al. Cell Reports
- HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer
- (2020) Holly Brunton et al. Cell Reports
- Molecular subtypes of pancreatic cancer
- (2019) Eric A. Collisson et al. Nature Reviews Gastroenterology & Hepatology
- Multi-omic molecular comparison of primary versus metastatic pancreatic tumours
- (2019) Gagandeep Brar et al. BRITISH JOURNAL OF CANCER
- Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer
- (2019) Talia Golan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Beyond Synthetic Lethality: Charting the Landscape of Pairwise Gene Expression States Associated with Survival in Cancer
- (2019) Assaf Magen et al. Cell Reports
- How Does SUMO Participate in Spindle Organization?
- (2019) Abrieu et al. Cells
- Pancreatic Cancer Organoids for Determining Sensitivity to Bromodomain and Extra-Terminal Inhibitors (BETi)
- (2019) Benjamin Bian et al. Frontiers in Oncology
- PML hyposumoylation is responsible for the resistance of pancreatic cancer
- (2019) Mirna Swayden et al. FASEB JOURNAL
- Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
- (2019) Scott Kopetz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oncogenic MYC amplifies mitotic perturbations
- (2019) Samantha Littler et al. Open Biology
- Multiomics Prediction of Response Rates to Therapies to Inhibit Programmed Cell Death 1 and Programmed Cell Death 1 Ligand 1
- (2019) Joo Sang Lee et al. JAMA Oncology
- A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer
- (2019) Stefanie Schmidt et al. NATURE CELL BIOLOGY
- Synthetic lethality as an engine for cancer drug target discovery
- (2019) Alan Huang et al. NATURE REVIEWS DRUG DISCOVERY
- SUMOylation homeostasis in tumorigenesis
- (2019) Minyue Xie et al. CANCER LETTERS
- Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway
- (2018) Maiyon Park et al. BMC Complementary and Alternative Medicine
- Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors
- (2018) Jaclyn Andricovich et al. CANCER CELL
- Protein neddylation and its alterations in human cancers for targeted therapy
- (2018) Lisha Zhou et al. CELLULAR SIGNALLING
- SUMO-specific proteases and isopeptidases of the SENP family at a glance
- (2018) Kathrin Kunz et al. JOURNAL OF CELL SCIENCE
- Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer
- (2018) Na Zhao et al. JOURNAL OF CLINICAL INVESTIGATION
- IRE1α RNase–dependent lipid homeostasis promotes survival in Myc-transformed cancers
- (2018) Hong Xie et al. JOURNAL OF CLINICAL INVESTIGATION
- The functional roles of PML nuclear bodies in genome maintenance
- (2018) Hae Ryung Chang et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Synthetic lethal therapies for cancer: what’s next after PARP inhibitors?
- (2018) Alan Ashworth et al. Nature Reviews Clinical Oncology
- PLK1 inhibition targets Myc-activated malignant glioma cells irrespective of mismatch repair deficiency-mediated acquired resistance to temozolomide
- (2018) Fumi Higuchi et al. MOLECULAR CANCER THERAPEUTICS
- SUMO-Mediated Regulation of Nuclear Functions and Signaling Processes
- (2018) Xiaolan Zhao MOLECULAR CELL
- Triptolide as a novel agent in pancreatic cancer: the validation using patient derived pancreatic tumor cell line
- (2018) Seung Tae Kim et al. BMC CANCER
- Systemic treatment of pancreatic cancer revisited
- (2018) Michel Ducreux et al. SEMINARS IN ONCOLOGY
- Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme
- (2018) Zongyang Lv et al. Nature Communications
- Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor
- (2017) Xingyue He et al. Nature Chemical Biology
- Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation
- (2017) Ivo A Hendriks et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation
- (2017) Ivo A Hendriks et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Affimer proteins are versatile and renewable affinity reagents
- (2017) Christian Tiede et al. eLife
- Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3-MYC Interactions as a Target in Pancreatic Cancer
- (2016) N. Beglyarova et al. CLINICAL CANCER RESEARCH
- GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer
- (2016) Paola Martinelli et al. GUT
- Concepts to Target MYC in Pancreatic Cancer
- (2016) M. Wirth et al. MOLECULAR CANCER THERAPEUTICS
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
- (2016) Dai Horiuchi et al. NATURE MEDICINE
- A comprehensive compilation of SUMO proteomics
- (2016) Ivo A. Hendriks et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Oncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents
- (2016) David Perera et al. Scientific Reports
- Myc and cell cycle control
- (2015) Gabriel Bretones et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- MYC Is a Major Determinant of Mitotic Cell Fate
- (2015) Caroline Topham et al. CANCER CELL
- Knockdown of SUMO-activating enzyme subunit 2 (SAE2) suppresses cancer malignancy and enhances chemotherapy sensitivity in small cell lung cancer
- (2015) Xiaoke Liu et al. Journal of Hematology & Oncology
- MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
- (2015) Cheryl M. Koh et al. NATURE
- MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies
- (2015) E Hessmann et al. ONCOGENE
- Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
- (2015) Agnieszka K. Witkiewicz et al. Nature Communications
- Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis
- (2015) Jiguang Ma et al. Oncotarget
- Non-nuclear function of sumoylated proteins
- (2014) Urszula Wasik et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma
- (2014) A. Hoellein et al. BLOOD
- Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening
- (2014) Zongxiang Zhou et al. BMC CANCER
- CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma
- (2014) Chun-Hao Huang et al. GENES & DEVELOPMENT
- Wrestling with stress: Roles of protein SUMOylation and deSUMOylation in cell stress response
- (2014) Chun Guo et al. IUBMB LIFE
- Identification of New Mechanisms of Cellular Response to Chemotherapy by Tracking Changes in Post-Translational Modifications by Ubiquitin and Ubiquitin-Like Proteins
- (2014) Thomas Bonacci et al. JOURNAL OF PROTEOME RESEARCH
- Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications
- (2014) Christian Tiede et al. PROTEIN ENGINEERING DESIGN & SELECTION
- SUMO-specific protease 1 regulates pancreatic cancer cell proliferation and invasion by targeting MMP-9
- (2014) Chenchao Ma et al. TUMOR BIOLOGY
- Discovery of small molecule inhibitors targeting the SUMO–SIM interaction using a protein interface consensus approach
- (2014) Arnout R. D. Voet et al. MedChemComm
- The ROS/SUMO Axis Contributes to the Response of Acute Myeloid Leukemia Cells to Chemotherapeutic Drugs
- (2014) Guillaume Bossis et al. Cell Reports
- Synthetic Lethal Screens as a Means to Understand and Treat MYC-Driven Cancers
- (2014) S. Cermelli et al. Cold Spring Harbor Perspectives in Medicine
- Sumoylation: A Regulatory Protein Modification in Health and Disease
- (2013) Annette Flotho et al. Annual Review of Biochemistry
- PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cells
- (2013) W Chien et al. BRITISH JOURNAL OF CANCER
- MYC on the Path to Cancer
- (2012) Chi V. Dang CELL
- SUMOylation in Control of Accurate Chromosome Segregation during Mitosis
- (2012) Jun Wan et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
- (2012) Dai Horiuchi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Two Distinct Populations of Exosomes Are Released from LIM1863 Colon Carcinoma Cell-derived Organoids
- (2012) Bow J. Tauro et al. MOLECULAR & CELLULAR PROTEOMICS
- An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735
- (2012) K. E. Hook et al. MOLECULAR CANCER THERAPEUTICS
- Deregulated MYC expression induces dependence upon AMPK-related kinase 5
- (2012) Lidan Liu et al. NATURE
- Triptolide Inhibits the Proliferation of Prostate Cancer Cells and Down-Regulates SUMO-Specific Protease 1 Expression
- (2012) Weiwei Huang et al. PLoS One
- Gold nanoparticles as a platform for creating a multivalent poly-SUMO chain inhibitor that also augments ionizing radiation
- (2012) Y.-J. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional genomics identifies therapeutic targets for MYC-driven cancer
- (2012) M. Toyoshima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- XPB, a subunit of TFIIH, is a target of the natural product triptolide
- (2011) Denis V Titov et al. Nature Chemical Biology
- Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
- (2011) Eric A Collisson et al. NATURE MEDICINE
- Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors
- (2011) Matilde Murga et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells
- (2011) J Wang et al. ONCOGENE
- A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
- (2011) J. D. Kessler et al. SCIENCE
- Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state
- (2010) J. den Hollander et al. BLOOD
- Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
- (2010) D. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate
- (2009) Isao Fukuda et al. CHEMISTRY & BIOLOGY
- Cdk2 suppresses cellular senescence induced by the c-myc oncogene
- (2009) Stefano Campaner et al. NATURE CELL BIOLOGY
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