PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
Authors
Keywords
-
Journal
NATURE MEDICINE
Volume 22, Issue 11, Pages 1321-1329
Publisher
Springer Nature
Online
2016-10-24
DOI
10.1038/nm.4213
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
- (2016) Fara Brasó-Maristany et al. NATURE MEDICINE
- Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies
- (2015) Matthew T. Burger et al. JOURNAL OF MEDICINAL CHEMISTRY
- MYC is a critical target of FBXW7
- (2015) Mai Sato et al. Oncotarget
- FastRFunctions for Robust Correlations and Hierarchical Clustering
- (2015) Peter Langfelder et al. Journal of Statistical Software
- Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
- (2014) P. D. Garcia et al. CLINICAL CANCER RESEARCH
- PIM Kinase Inhibitor AZD1208 for Treatment of MYC-Driven Prostate Cancer
- (2014) Austin N. Kirschner et al. JNCI-Journal of the National Cancer Institute
- Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation
- (2013) J. Lu et al. BLOOD
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
- (2013) Peter E. Czabotar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Successive Phosphorylation of p27KIP1Protein at Serine-10 and C Terminus Crucially Controls Its Potency to Inactivate Cdk2
- (2012) Atish R. Mohanty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
- (2012) Dai Horiuchi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Proto-oncogene PIM-1 is a novel estrogen receptor target associating with high grade breast tumors
- (2012) Marjo Malinen et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia
- (2011) L. S. Chen et al. BLOOD
- Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
- (2011) Laura J. Esserman et al. BREAST CANCER RESEARCH AND TREATMENT
- Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland
- (2011) X. Wang et al. CANCER RESEARCH
- A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer
- (2011) Christos Hatzis JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
- (2011) Yoko S DeRose et al. NATURE MEDICINE
- Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells
- (2011) J Wang et al. ONCOGENE
- A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
- (2011) J. D. Kessler et al. SCIENCE
- p16INK4a-mediated suppression of telomerase in normal and malignant human breast cells
- (2010) Alexey V. Bazarov et al. AGING CELL
- Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes
- (2010) Alexey V. Bazarov et al. CELL CYCLE
- Triple-Negative Breast Cancer
- (2010) William D. Foulkes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma
- (2010) J Wang et al. ONCOGENE
- Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells
- (2009) L. S. Chen et al. BLOOD
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- Pim Kinases Promote Cell Cycle Progression by Phosphorylating and Down-regulating p27Kip1 at the Transcriptional and Posttranscriptional Levels
- (2008) D. Morishita et al. CANCER RESEARCH
- Pim kinase-dependent inhibition of c-Myc degradation
- (2008) Y Zhang et al. ONCOGENE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now