Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor
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Title
Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor
Authors
Keywords
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Journal
Nature Chemical Biology
Volume 13, Issue 11, Pages 1164-1171
Publisher
Springer Nature
Online
2017-09-11
DOI
10.1038/nchembio.2463
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Note: Only part of the references are listed.- Pevonedistat (MLN4924), a First-in-Class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study
- (2015) Ronan T. Swords et al. BRITISH JOURNAL OF HAEMATOLOGY
- Knockdown of SUMO-activating enzyme subunit 2 (SAE2) suppresses cancer malignancy and enhances chemotherapy sensitivity in small cell lung cancer
- (2015) Xiaoke Liu et al. Journal of Hematology & Oncology
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- (2015) Bing Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) Prabha Sarangi et al. TRENDS IN BIOCHEMICAL SCIENCES
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- (2015) Karolin Eifler et al. TRENDS IN BIOCHEMICAL SCIENCES
- Roles for SUMO in pre-mRNA processing
- (2015) Patrick K. Nuro-Gyina et al. Wiley Interdisciplinary Reviews-RNA
- A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver
- (2015) Miyuki Suzawa et al. eLife
- Characterization of the Loss of SUMO Pathway Function on Cancer Cells and Tumor Proliferation
- (2015) Xingyue He et al. PLoS One
- Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma
- (2014) A. Hoellein et al. BLOOD
- Sumoylation Pathway Is Required to Maintain the Basal Breast Cancer Subtype
- (2014) Maria V. Bogachek et al. CANCER CELL
- Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata
- (2014) Misao Takemoto et al. JOURNAL OF ANTIBIOTICS
- PHD3-SUMO conjugation represses HIF1 transcriptional activity independently of PHD3 catalytic activity
- (2014) A. Nunez-O'Mara et al. JOURNAL OF CELL SCIENCE
- Spectomycin B1 as a Novel SUMOylation Inhibitor That Directly Binds to SUMO E2
- (2013) Mikako Hirohama et al. ACS Chemical Biology
- Absolute Quantification of E1, Ubiquitin-Like Proteins and Nedd8–MLN4924 Adduct by Mass Spectrometry
- (2013) Xiaofeng Yang et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- An Electrophoretic Mobility Shift Assay Identifies a Mechanistically Unique Inhibitor of Protein Sumoylation
- (2013) Yeong Sang Kim et al. CHEMISTRY & BIOLOGY
- Detecting endogenous SUMO targets in mammalian cells and tissues
- (2013) Janina Becker et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- PML, SUMOylation, and Senescence
- (2013) Lisa Ivanschitz et al. Frontiers in Oncology
- Treatment-Emergent Mutations in NAEβ Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924
- (2012) Michael A. Milhollen et al. CANCER CELL
- Protein Group Modification and Synergy in the SUMO Pathway as Exemplified in DNA Repair
- (2012) Ivan Psakhye et al. CELL
- SUMOylation in Control of Accurate Chromosome Segregation during Mitosis
- (2012) Jun Wan et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Mechanistic Studies of Substrate-assisted Inhibition of Ubiquitin-activating Enzyme by Adenosine Sulfamate Analogues
- (2011) Jesse J. Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
- (2011) J. D. Kessler et al. SCIENCE
- Ubc9 expression predicts chemoresistance in breast cancer
- (2011) Shi-Feng Chen et al. Chinese Journal of Cancer
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Expression analysis of Ubc9, the single small ubiquitin-like modifier (SUMO) E2 conjugating enzyme, in normal and malignant tissues
- (2010) Stergios J. Moschos et al. HUMAN PATHOLOGY
- Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ
- (2010) James E. Brownell et al. MOLECULAR CELL
- The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
- (2010) Jaclyn R. Gareau et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- SUMO association with repressor complexes, emerging routes for transcriptional control
- (2009) Mario Garcia-Dominguez et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate
- (2009) Isao Fukuda et al. CHEMISTRY & BIOLOGY
- Kerriamycin B inhibits protein SUMOylation
- (2009) Isao Fukuda et al. JOURNAL OF ANTIBIOTICS
- Protection from Isopeptidase-Mediated Deconjugation Regulates Paralog-Selective Sumoylation of RanGAP1
- (2009) Shanshan Zhu et al. MOLECULAR CELL
- The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
- (2009) Joanna R. Morris et al. NATURE
- Principles of ubiquitin and SUMO modifications in DNA repair
- (2009) Steven Bergink et al. NATURE
- An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
- (2009) Teresa A. Soucy et al. NATURE
- System-Wide Changes to SUMO Modifications in Response to Heat Shock
- (2009) F. Golebiowski et al. Science Signaling
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- (2008) Ryo Sakasai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging roles of the SUMO pathway in mitosis
- (2008) Mary Dasso Cell Division
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