PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cells

STAT5b as Molecular Target in Pancreatic Cancer—Inhibition of Tumor Growth, Angiogenesis, and Metastases

(2015) Christian Moser et al.   NEOPLASIA

STAT3 Plays a Critical Role in KRAS-Induced Pancreatic Tumorigenesis

(2011) R. B. Corcoran et al.   CANCER RESEARCH

IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer

(2011) M. S. Anglesio et al.   CLINICAL CANCER RESEARCH

SYT-SSX1 (Synovial Sarcoma Translocated) Regulates PIASy Ligase Activity to Cause Overexpression of NCOA3 Protein

(2011) Yin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

The Expression of Histone Demethylase JMJD1A in Renal Cell Carcinoma

(2011) X. GUO et al.   NEOPLASMA

Mechanisms, regulation and consequences of protein SUMOylation

(2010) Kevin A. Wilkinson et al.   BIOCHEMICAL JOURNAL

Jumonji Domain Containing 1A Is a Novel Prognostic Marker for Colorectal Cancer: In vivo Identification from Hypoxic Tumor Cells

(2010) M. Uemura et al.   CLINICAL CANCER RESEARCH

Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Single-Agent Gemcitabine As First-Line Treatment of Patients With Advanced Pancreatic Cancer: The GIP-1 Study

(2010) Giuseppe Colucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

PIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxia

(2010) X Kang et al.   ONCOGENE

Hypoxia Inactivates the VHL Tumor Suppressor through PIASy-Mediated SUMO Modification

(2010) Qiliang Cai et al.   PLoS One

Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization

(2010) Qiliang Cai et al.   PLoS One

A candidate targeting molecule of insulin-like growth factor-I receptor for gastrointestinal cancers

(2010) Yasushi Adachi   WORLD JOURNAL OF GASTROENTEROLOGY

Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1  Enhances Hypoxic Gene Expression and Tumor Growth

(2009) A. J. Krieg et al.   MOLECULAR AND CELLULAR BIOLOGY

Overexpression of the Oxygen Sensors PHD-1, PHD-2, PHD-3, and FIH Is Associated with Tumor Aggressiveness in Pancreatic Endocrine Tumors

(2008) A. Couvelard et al.   CLINICAL CANCER RESEARCH

The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF

(2008) Sophie Beyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY