Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging
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Title
Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging
Authors
Keywords
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Journal
AGING CELL
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-10-09
DOI
10.1111/acel.13256
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Note: Only part of the references are listed.- Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2
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- (2020) Oliver Robinson et al. AGING CELL
- Prediction of chronological and biological age from laboratory data
- (2020) Luke Sagers et al. Aging-US
- Benefits of Metformin in Attenuating the Hallmarks of Aging
- (2020) Ameya S. Kulkarni et al. Cell Metabolism
- The quest to slow ageing through drug discovery
- (2020) Linda Partridge et al. NATURE REVIEWS DRUG DISCOVERY
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- (2020) Darshan S. Chandrashekar et al. ONCOGENE
- Systematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age
- (2020) Adiv A. Johnson et al. AGEING RESEARCH REVIEWS
- Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities
- (2020) Fedor Galkin et al. AGEING RESEARCH REVIEWS
- Human Gut Microbiome Aging Clock Based on Taxonomic Profiling and Deep Learning
- (2020) Fedor Galkin et al. iScience
- Using the drug-protein interactome to identify anti-ageing compounds for humans
- (2019) Matías Fuentealba et al. PLoS Computational Biology
- Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer’s Disease Model
- (2019) Mario Merlini et al. NEURON
- The Genetics of Aging: A Vertebrate Perspective
- (2019) Param Priya Singh et al. CELL
- Glycine supplementation extends lifespan of male and female mice
- (2019) Richard A. Miller et al. AGING CELL
- SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue
- (2019) Lin Shuai et al. DIABETES
- WebGestalt 2019: gene set analysis toolkit with revamped UIs and APIs
- (2019) Yuxing Liao et al. NUCLEIC ACIDS RESEARCH
- Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice
- (2019) Mitsukuni Yoshida et al. Cell Metabolism
- Wwp2 maintains cartilage homeostasis through regulation of Adamts5
- (2019) Sho Mokuda et al. Nature Communications
- The role of lipid metabolism in aging, lifespan regulation, and age‐related disease
- (2019) Adiv A. Johnson et al. AGING CELL
- Alliance of Genome Resources Portal: unified model organism research platform
- (2019) et al. NUCLEIC ACIDS RESEARCH
- Revamping the evolutionary theories of aging
- (2019) Adiv A. Johnson et al. AGEING RESEARCH REVIEWS
- Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production
- (2019) Luke S. Tain et al. AGING CELL
- Lipid Hydrolase Enzymes: Pragmatic Prolongevity Targets for Improved Human Healthspan?
- (2019) Adiv A. Johnson REJUVENATION RESEARCH
- RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury
- (2019) Xinzhou Zhu et al. Nature Communications
- PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer
- (2019) Tânia D. F. Costa et al. Nature Communications
- Plasma protein patterns as comprehensive indicators of health
- (2019) Stephen A. Williams et al. NATURE MEDICINE
- Undulating changes in human plasma proteome profiles across the lifespan
- (2019) Benoit Lehallier et al. NATURE MEDICINE
- Effects of Intermittent Fasting on Health, Aging, and Disease
- (2019) Rafael de Cabo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Plasma proteomic signature of age in healthy humans
- (2018) Toshiko Tanaka et al. AGING CELL
- Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development
- (2018) Michael S Nahorski et al. BRAIN
- DNA methylation-based biomarkers and the epigenetic clock theory of ageing
- (2018) Steve Horvath et al. NATURE REVIEWS GENETICS
- Machine Learning on Human Muscle Transcriptomic Data for Biomarker Discovery and Tissue-Specific Drug Target Identification
- (2018) Polina Mamoshina et al. Frontiers in Genetics
- Habitual Aerobic Exercise and Circulating Proteomic Patterns in Healthy Adults: Relation to Indicators of Healthspan
- (2018) Jessica R. Santos-Parker et al. JOURNAL OF APPLIED PHYSIOLOGY
- Genomic atlas of the human plasma proteome
- (2018) Benjamin B. Sun et al. NATURE
- Inhibiting amyloid-ß cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design
- (2018) Qin Cao et al. Nature Chemistry
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- (2018) Se Hoon Choi et al. SCIENCE
- Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases
- (2018) Marialbert Acosta-Herrera et al. ANNALS OF THE RHEUMATIC DISEASES
- Late-onset administration of GDF11 extends life span and delays development of age-related markers in the annual fish Nothobranchius guentheri
- (2018) Yang Zhou et al. BIOGERONTOLOGY
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- (2018) Hui-Ming Chen et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2018) Jae Kyu Ryu et al. NATURE IMMUNOLOGY
- UniProt: a worldwide hub of protein knowledge
- (2018) NUCLEIC ACIDS RESEARCH
- Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors
- (2017) Emanuele Di Angelantonio et al. LANCET
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- (2017) Peng Liu et al. NATURE
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- (2017) Joseph M. Castellano et al. NATURE
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- (2017) Denise N Slenter et al. NUCLEIC ACIDS RESEARCH
- Human Ageing Genomic Resources: new and updated databases
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- (2015) Lucas K Smith et al. NATURE MEDICINE
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- (2015) Nuria Garatachea et al. REJUVENATION RESEARCH
- The transcriptional landscape of age in human peripheral blood
- (2015) Marjolein J. Peters et al. Nature Communications
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- (2015) Jae Kyu Ryu et al. Nature Communications
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- (2015) Jerome Friedman et al. Journal of Statistical Software
- Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations
- (2014) Mark W. Russell et al. HUMAN MOLECULAR GENETICS
- Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
- (2014) Bhama Ramkhelawon et al. NATURE MEDICINE
- AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner
- (2014) Matthew Ulgherait et al. Cell Reports
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- (2014) Matthew Traylor et al. PLoS Genetics
- The Ubiquitin-fold Modifier 1 (Ufm1) Cascade ofCaenorhabditis elegans
- (2013) Patrick Hertel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Influence of Shc Proteins on Life Span in Mice
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- (2013) T. Kim et al. SCIENCE
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- (2013) Steve Horvath GENOME BIOLOGY
- GLAD4U: deriving and prioritizing gene lists from PubMed literature
- (2012) Jérôme Jourquin et al. BMC GENOMICS
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- Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity
- (2012) Ana Ortega-Molina et al. Cell Metabolism
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- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques
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- (2011) Emidio E. Pistilli et al. JOURNAL OF CLINICAL INVESTIGATION
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice
- (2010) Monique C. de Waard et al. ACTA NEUROPATHOLOGICA
- Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene
- (2010) Kristina Hedbacker et al. Cell Metabolism
- p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients
- (2010) M. K. Y. Siu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-15 Receptor Deletion Results in Circadian Changes of Locomotor and Metabolic Activity
- (2009) Yi He et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
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- (2009) Alvin C Lin et al. NATURE MEDICINE
- MMP12,Lung Function, and COPD in High-Risk Populations
- (2009) Gary M. Hunninghake et al. NEW ENGLAND JOURNAL OF MEDICINE
- Expression of Pla2g2a prevents carcinogenesis in Muc2-deficient mice
- (2008) R. J. A. Fijneman et al. CANCER SCIENCE
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