Machine Learning on Human Muscle Transcriptomic Data for Biomarker Discovery and Tissue-Specific Drug Target Identification

Population Specific Biomarkers of Human Aging: A Big Data Study Using South Korean, Canadian, and Eastern European Patient Populations

(2018) Polina Mamoshina et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

druGAN: An Advanced Generative Adversarial Autoencoder Model for de Novo Generation of New Molecules with Desired Molecular Properties in Silico

(2017) Artur Kadurin et al.   MOLECULAR PHARMACEUTICS

Metformin; a review of its history and future: from lilac to longevity

(2017) Inas Thomas et al.   PEDIATRIC DIABETES

mTOR as a Key Regulator in Maintaining Skeletal Muscle Mass

(2017) Mee-Sup Yoon   Frontiers in Physiology

In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state

(2016) Alexander Aliper et al.   Aging-US

Deep Feature Selection: Theory and Application to Identify Enhancers and Promoters

(2016) Yifeng Li et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Applications of Deep Learning in Biomedicine

(2016) Polina Mamoshina et al.   MOLECULAR PHARMACEUTICS

In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development

(2016) Ivan V. Ozerov et al.   Nature Communications

The cornucopia of meaningful leads: Applying deep adversarial autoencoders for new molecule development in oncology

(2016) Artur Kadurin et al.   Oncotarget

Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease

(2015) Alexey Moskalev et al.   Aging-US

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The transcriptional landscape of age in human peripheral blood

(2015) Marjolein J. Peters et al.   Nature Communications

Major aging-associated RNA expressions change at two distinct age-positions

(2014) Marius Gheorghe et al.   BMC GENOMICS

Myosteatosis and myofibrosis: Relationship with aging, inflammation and insulin resistance

(2013) Elena Zoico et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Microarray Analysis Reveals Novel Features of the Muscle Aging Process in Men and Women

(2013) Dongmei Liu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Molecular Networks of Human Muscle Adaptation to Exercise and Age

(2013) Bethan E. Phillips et al.   PLoS Genetics

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Age-Related Defects in Erythrocyte 2,3-Diphosphoglycerate Metabolism in Dementia

(2013) Yury Kaminsky et al.   Aging and Disease

Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults

(2012) Ulrika Raue et al.   JOURNAL OF APPLIED PHYSIOLOGY

Structural, biochemical, cellular, and functional changes in skeletal muscle extracellular matrix with aging

(2011) T. W. Kragstrup et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle

(2010) Eija Pöllänen et al.   AGE

Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans

(2010) James A. Timmons et al.   JOURNAL OF APPLIED PHYSIOLOGY

A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype

(2010) Pernille Keller et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

(2010) Karsten Lenk et al.   Journal of Cachexia Sarcopenia and Muscle

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH