Protein-Related Circular RNAs in Human Pathologies

Translation and functional roles of circular RNAs in human cancer

(2020) Ming Lei et al.   Molecular Cancer

Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

(2020) Pan Wu et al.   Molecular Cancer

Functions and clinical significance of circular RNAs in glioma

(2020) Jikui Sun et al.   Molecular Cancer

The Role of microRNAs, Long Non-coding RNAs, and Circular RNAs in Cervical Cancer

(2020) Maria Lina Tornesello et al.   Frontiers in Oncology

CircAKT3 inhibits glycolysis balance in lung cancer cells by regulating miR-516b-5p/STAT3 to inhibit cisplatin sensitivity

(2020) Yangling Xu et al.   BIOTECHNOLOGY LETTERS

Circular RNA in Diseased Heart

(2020) Ying Wang et al.   Cells

Readers of the m6A epitranscriptomic code

(2019) Soizik Berlivet et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

(2019) Bethsebie Lalduhsaki Sailo et al.   Cancers

Deregulation of Circular RNAs in Cancer From the Perspectives of Aberrant Biogenesis, Transport and Removal

(2019) Qiongqiong Wu et al.   Frontiers in Genetics

Expanded Expression Landscape and Prioritization of Circular RNAs in Mammals

(2019) Peifeng Ji et al.   Cell Reports

Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

(2019) Ok Hyun Park et al.   MOLECULAR CELL

A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

(2019) Xiao Zheng et al.   Molecular Cancer

IRES Trans-Acting Factors, Key Actors of the Stress Response

(2019) Anne-Claire Godet et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Landscape of Circular RNA in Cancer

(2019) Josh N. Vo et al.   CELL

Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity

(2019) Chu-Xiao Liu et al.   CELL

Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

(2019) Xiaoxu Huang et al.   Molecular Cancer

The role of m6A RNA methylation in human cancer

(2019) Xiao-Yu Chen et al.   Molecular Cancer

Past, present, and future of circ RNA s

(2019) Ines Lucia Patop et al.   EMBO JOURNAL

circLgr4 drives colorectal tumorigenesis and invasion through Lgr4‐targeting peptide

(2019) Xiaofei Zhi et al.   INTERNATIONAL JOURNAL OF CANCER

Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

(2019) Peng-Fei Zhang et al.   Molecular Cancer

Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

(2019) Jiawei Zhao et al.   Nature Communications

Roles of CircRNAs in Autoimmune Diseases

(2019) Xin Xia et al.   Frontiers in Immunology

Functions and Potential Applications of Circular RNAs in Cancer Stem Cells

(2019) Ziyang Feng et al.   Frontiers in Oncology

Circular RNAs: Biogenesis, Mechanism, and Function in Human Cancers

(2019) Xing Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An Overview of Circular RNAs and Their Implications in Myotonic Dystrophy

(2019) Karol Czubak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1

(2019) Xin Xia et al.   Molecular Cancer

Predicting circRNA-Disease Associations Based on circRNA Expression Similarity and Functional Similarity

(2019) Yongtian Wang et al.   Frontiers in Genetics

Distinct functions of AKT isoforms in breast cancer: a comprehensive review

(2019) Nico Hinz et al.   Cell Communication and Signaling

Exploring the Regulatory Role of Circular RNAs in Neurodegenerative Disorders

(2019) Eleonora D’Ambra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals

(2019) Dingwei Xue et al.   Molecular Cancer

ncRNA-Encoded Peptides or Proteins and Cancer

(2019) Jizhong Wang et al.   MOLECULAR THERAPY

Recent Progress on Circular RNA Research in Acute Myeloid Leukemia

(2019) Muhammad Jamal et al.   Frontiers in Oncology

m6A mRNA methylation regulates CTNNB1 to promote the proliferation of hepatoblastoma

(2019) Li Liu et al.   Molecular Cancer

circFBXW7 Inhibits Malignant Progression by Sponging miR-197-3p and Encoding a 185-aa Protein in Triple-Negative Breast Cancer

(2019) Feng Ye et al.   Molecular Therapy-Nucleic Acids

Different roles of circular RNAs with protein coding potentials

(2018) Angshuman Bagchi   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Downregulated circular RNA hsa_circ_0001649 regulates proliferation, migration and invasion in cholangiocarcinoma cells

(2018) Yi Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hsa_circ_0001649: A circular RNA and potential novel biomarker for colorectal cancer

(2018) Wenxin Ji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hidden Peptides Encoded by Putative Noncoding RNAs

(2018) Akinobu Matsumoto et al.   CELL STRUCTURE AND FUNCTION

Microarray Expression Profile of Circular RNAs in Peripheral Blood Mononuclear Cells from Active Tuberculosis Patients

(2018) Zi-Kun Huang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Decreased circular RNA hsa_circ_0001649 predicts unfavorable prognosis in glioma and exerts oncogenic properties in vitro and in vivo

(2018) Yu Wang et al.   GENE

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis

(2018) Maolei Zhang et al.   ONCOGENE

The Role of Dynamic m6 A RNA Methylation in Photobiology

(2018) Myles Robinson et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Functional sequestration of microRNA-122 from Hepatitis C Virus by circular RNA sponges

(2018) Isabelle Jost et al.   RNA Biology

Functional role of circular RNAs in cancer development and progression

(2018) Wei Lun Ng et al.   RNA Biology

Potential Diagnostic Power of Blood Circular RNA Expression in Active Pulmonary Tuberculosis

(2018) Zhongqing Qian et al.   EBioMedicine

Circular RNAs: Methodological challenges and perspectives in cardiovascular diseases

(2018) Matteo Carrara et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The emerging landscape of circular RNA in cardiovascular diseases

(2018) Meng-yuan Zhou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies

(2018) Mette Dahl et al.   LABORATORY INVESTIGATION

FBXW7: a critical tumor suppressor of human cancers

(2018) Chien-Hung Yeh et al.   Molecular Cancer

Circular RNAs: Crucial regulators in the human body (Review)

(2018) Yuanyong Wang et al.   ONCOLOGY REPORTS

Synthetic circular RNA functions as a miR-21 sponge to suppress gastric carcinoma cell proliferation

(2018) Xi Liu et al.   Molecular Therapy-Nucleic Acids

A comprehensive review of circRNA: from purification and identification to disease marker potential

(2018) Sheng Xu et al.   PeerJ

Circular RNAs in Muscle Function and Disease

(2018) Simona Greco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CircRNA ZNF609 functions as a competitive endogenous RNA to regulate FOXP4 expression by sponging miR-138-5p in renal carcinoma

(2018) Yunhe Xiong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The interaction of circRNAs and RNA binding proteins: An important part of circRNA maintenance and function

(2018) Jiankun Zang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma

(2018) Maolei Zhang et al.   Nature Communications

Circular RNAs as Therapeutic Agents and Targets

(2018) Lesca M. Holdt et al.   Frontiers in Physiology

hsa_circ_0013958: a circular RNA and potential novel biomarker for lung adenocarcinoma

(2017) Xiaoli Zhu et al.   FEBS Journal

The emerging role of circular RNAs in transcriptome regulation

(2017) S. Huang et al.   GENOMICS

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

(2017) Ivano Legnini et al.   MOLECULAR CELL

Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection

(2017) Xiang Li et al.   MOLECULAR CELL

ZKSCAN1gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways

(2017) Zhicheng Yao et al.   Molecular Oncology

The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function

(2017) Zhen-Guo Yang et al.   MOLECULAR THERAPY

Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them

(2017) Kathrin Leppek et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Circular RNAs in cancer: opportunities and challenges in the field

(2017) L S Kristensen et al.   ONCOGENE

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

(2017) Kotb Abdelmohsen et al.   RNA Biology

ALU ternative Regulation for Gene Expression

(2017) Ling-Ling Chen et al.   TRENDS IN CELL BIOLOGY

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

(2017) Lorenzo Errichelli et al.   Nature Communications

Polymorphisms and expression pattern of circular RNA circ-ITCH contributes to the carcinogenesis of hepatocellular carcinoma

(2017) Wenzhi Guo et al.   Oncotarget

Peripheral blood circular RNA hsa_circ_0124644 can be used as a diagnostic biomarker of coronary artery disease

(2017) Zhenzhou Zhao et al.   Scientific Reports

A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair

(2017) Yan Zeng et al.   Theranostics

Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs

(2017) Chan Zhou et al.   Cell Reports

Circular RNAs: Biogenesis, Function, and a Role as Possible Cancer Biomarkers

(2017) Luka Bolha et al.   International Journal of Genomics

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

(2017) Yibing Yang et al.   JNCI-Journal of the National Cancer Institute

Hsa_circ_0054633 in peripheral blood can be used as a diagnostic biomarker of pre-diabetes and type 2 diabetes mellitus

(2016) Zhenzhou Zhao et al.   ACTA DIABETOLOGICA

Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity

(2016) William W Du et al.   CELL DEATH AND DIFFERENTIATION

The Wnt signaling pathway in cancer

(2016) Yann Duchartre et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Circular RNAs: analysis, expression and potential functions

(2016) Steven P. Barrett et al.   DEVELOPMENT

Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses

(2016) William W. Du et al.   EUROPEAN HEART JOURNAL

Circular RNA: a new star in neurological diseases

(2016) Tao-Ran Li et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Detecting circular RNAs: bioinformatic and experimental challenges

(2016) Linda Szabo et al.   NATURE REVIEWS GENETICS

Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins

(2016) Harmen van Andel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circular RNA Expression: Its Potential Regulation and Function

(2016) Julia Salzman   TRENDS IN GENETICS

HPV 16 E7 inhibits OSCC cell proliferation, invasion, and metastasis by upregulating the expression of miR-20a

(2016) Jun Hu et al.   TUMOR BIOLOGY

PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

(2016) Xiaoman Li et al.   Oncotarget

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Using circular RNA as a novel type of biomarker in the screening of gastric cancer

(2015) Peifei Li et al.   CLINICA CHIMICA ACTA

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs

(2015) Dawood B. Dudekula et al.   RNA Biology

Regulation of circRNA biogenesis

(2015) Ling-Ling Chen et al.   RNA Biology

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

AKT3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf & TSC1/TSC2

(2015) Hui-Ping Lin et al.   Oncotarget

Rolling Circle Translation of Circular RNA in Living Human Cells

(2015) Naoko Abe et al.   Scientific Reports

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Novel coding, translation, and gene expression of a replicating covalently closed circular RNA of 220 nt

(2014) Mounir Georges AbouHaidar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient backsplicing produces translatable circular mRNAs

(2014) Yang Wang et al.   RNA

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Correction: Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA