Receptors Mediating Host-Microbiota Communication in the Metaorganism: The Invertebrate Perspective

The quest for an animal model of coral health and disease

(2020) Ellen P. Neff   LAB ANIMAL

TGFβ/BMP immune signaling affects abundance and function of C. elegans gut commensals

(2019) Maureen Berg et al.   Nature Communications

Natural C. elegans Microbiota Protects against Infection via Production of a Cyclic Lipopeptide of the Viscosin Group

(2019) Kohar A.B. Kissoyan et al.   CURRENT BIOLOGY

Evolutionary “Experiments” in Symbiosis: The Study of Model Animals Provides Insights into the Mechanisms Underlying the Diversity of Host–Microbe Interactions

(2019) Thomas C. G. Bosch et al.   BIOESSAYS

A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology

(2019) Haiwei Chen et al.   CELL

Enterococcus faecium secreted antigen A generates muropeptides to enhance host immunity and limit bacterial pathogenesis

(2019) Byungchul Kim et al.   eLife

Mapping Interactions of Microbial Metabolites with Human G-Protein-Coupled Receptors

(2019) Dominic A. Colosimo et al.   Cell Host & Microbe

The functional repertoire contained within the native microbiota of the model nematode Caenorhabditis elegans

(2019) Johannes Zimmermann et al.   ISME Journal

Simple animal models for microbiome research

(2019) Angela E. Douglas   NATURE REVIEWS MICROBIOLOGY

The Inducible Response of the Nematode Caenorhabditis elegans to Members of Its Natural Microbiota Across Development and Adult Life

(2019) Wentao Yang et al.   Frontiers in Microbiology

A Phage Protein Aids Bacterial Symbionts in Eukaryote Immune Evasion

(2019) Martin T. Jahn et al.   Cell Host & Microbe

Cytosolic and Secreted Peptidoglycan-Degrading Enzymes in Drosophila Respectively Control Local and Systemic Immune Responses to Microbiota

(2018) Bernard Charroux et al.   Cell Host & Microbe

Drosophila Perpetuates Nutritional Mutualism by Promoting the Fitness of Its Intestinal Symbiont Lactobacillus plantarum

(2018) Gilles Storelli et al.   Cell Metabolism

Role of scavenger receptor from Octopus ocellatus as a co-receptor of Toll-like receptor in initiation of TLR-NF-κB signaling during anti-bacterial response

(2018) Xiumei Wei et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Intestinal Epithelial Wnt Signaling Mediates Acetylcholine-Triggered Host Defense against Infection

(2018) Sid Ahmed Labed et al.   IMMUNITY

The Drosophila model for microbiome research

(2018) Angela E. Douglas   LAB ANIMAL

Evolutionary Origins of Toll-like Receptor Signaling

(2018) Joseph J Brennan et al.   MOLECULAR BIOLOGY AND EVOLUTION

GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3

(2018) Ye Zhao et al.   Mucosal Immunology

Convergent shifts in host-associated microbial communities across environmentally elicited phenotypes

(2018) Tyler J. Carrier et al.   Nature Communications

PGRP-LD mediates A. stephensi vector competency by regulating homeostasis of microbiota-induced peritrophic matrix synthesis

(2018) Xiumei Song et al.   PLoS Pathogens

Toll-Like Receptors, Associated Biological Roles, and Signaling Networks in Non-Mammals

(2018) Li Nie et al.   Frontiers in Immunology

The sponge holobiont in a changing ocean: from microbes to ecosystems

(2018) L. Pita et al.   Microbiome

Transcriptional analyses provide new insight into the late-stage immune response of a diseased Caribbean coral

(2018) Lauren E. Fuess et al.   Royal Society Open Science

Microbiomes In Natura: Importance of Invertebrates in Understanding the Natural Variety of Animal-Microbe Interactions

(2018) Jillian M. Petersen et al.   mSystems

Early metazoan cell type diversity and the evolution of multicellular gene regulation

(2018) Arnau Sebé-Pedrós et al.   Nature Ecology & Evolution

Differential expression of immune receptors in two marine sponges upon exposure to microbial-associated molecular patterns

(2018) Lucía Pita et al.   Scientific Reports

Microbiota-Derived Lactate Activates Production of Reactive Oxygen Species by the Intestinal NADPH Oxidase Nox and Shortens Drosophila Lifespan

(2018) Igor Iatsenko et al.   IMMUNITY

Marine probiotics: increasing coral resistance to bleaching through microbiome manipulation

(2018) Phillipe M. Rosado et al.   ISME Journal

A gut microbial factor modulates locomotor behaviour in Drosophila

(2018) Catherine E. Schretter et al.   NATURE

Immune-suppression by OsHV-1 viral infection causes fatal bacteraemia in Pacific oysters

(2018) Julien de Lorgeril et al.   Nature Communications

Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition

(2017) Michail Mamantopoulos et al.   IMMUNITY

The bacterium Wolbachia exploits host innate immunity to establish a symbiotic relationship with the dengue vector mosquito Aedes aegypti

(2017) Xiaoling Pan et al.   ISME Journal

Commensal bacteria make GPCR ligands that mimic human signalling molecules

(2017) Louis J. Cohen et al.   NATURE

Host modification of a bacterial quorum-sensing signal induces a phenotypic switch in bacterial symbionts

(2017) Cleo Pietschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development

(2017) Joseph J. Brennan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimal nutrient exchange and immune responses operate in partner specificity in the cnidarian-dinoflagellate symbiosis

(2017) Jennifer L. Matthews et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A secreted antibacterial neuropeptide shapes the microbiome of Hydra

(2017) René Augustin et al.   Nature Communications

Distinct Roles of Sensory Neurons in Mediating Pathogen Avoidance and Neuropeptide-Dependent Immune Regulation

(2017) Xiou Cao et al.   Cell Reports

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition

(2017) Paul Lemire et al.   Cell Reports

Metabolite exchange between microbiome members produces compounds that influence Drosophila behavior

(2017) Caleb N Fischer et al.   eLife

Caenorhabditis elegans as a Model for Microbiome Research

(2017) Fan Zhang et al.   Frontiers in Microbiology

An Organismal Model for Gene Regulatory Networks in the Gut-Associated Immune Response

(2017) Katherine M. Buckley et al.   Frontiers in Immunology

Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling

(2017) Eva d’Hennezel et al.   mSystems

Intraspecific differences in molecular stress responses and coral pathobiome contribute to mortality under bacterial challenge in Acropora millepora

(2017) Rachel M. Wright et al.   Scientific Reports

Transcription factor NF-κB is modulated by symbiotic status in a sea anemone model of cnidarian bleaching

(2017) Katelyn M. Mansfield et al.   Scientific Reports

GPCRs in invertebrate innate immunity

(2016) Jerome Reboul et al.   BIOCHEMICAL PHARMACOLOGY

Hologenome analysis of two marine sponges with different microbiomes

(2016) Taewoo Ryu et al.   BMC GENOMICS

Transcriptomic and proteomic insights into innate immunity and adaptations to a symbiotic lifestyle in the gutless marine worm Olavius algarvensis

(2016) Juliane Wippler et al.   BMC GENOMICS

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

(2016) Tommi Vatanen et al.   CELL

Associations between transcriptional changes and protein phenotypes provide insights into immune regulation in corals

(2016) Lauren E. Fuess et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

C-type lectins: their network and roles in pathogen recognition and immunity

(2016) Sabine Mayer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

PGRP-SD, an Extracellular Pattern-Recognition Receptor, Enhances Peptidoglycan-Mediated Activation of the Drosophila Imd Pathway

(2016) Igor Iatsenko et al.   IMMUNITY

The regulation of host defences to infection by the microbiota

(2016) Rebecca L. Brown et al.   IMMUNOLOGY

Perturbation of gut bacteria induces a coordinated cellular immune response in the purple sea urchin larva

(2016) Eric CH Ho et al.   IMMUNOLOGY AND CELL BIOLOGY

The Human Intestinal Microbiome in Health and Disease

(2016) Susan V. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

A secreted bacterial peptidoglycan hydrolase enhances tolerance to enteric pathogens

(2016) K. J. Rangan et al.   SCIENCE

Sugar Coating the Envelope: Glycoconjugates for Microbe–Host Crosstalk

(2016) Hanne L.P. Tytgat et al.   TRENDS IN MICROBIOLOGY

Structure and evolutionary history of a large family of NLR proteins in the zebrafish

(2016) Kerstin Howe et al.   Open Biology

The Neuro-endocrinological Role of Microbial Glutamate and GABA Signaling

(2016) Roberto Mazzoli et al.   Frontiers in Microbiology

From the Lab to the Farm: An Industrial Perspective of Plant Beneficial Microorganisms

(2016) J. Jacob Parnell et al.   Frontiers in Plant Science

The scavenger receptor repertoire in six cnidarian species and its putative role in cnidarian-dinoflagellate symbiosis

(2016) Emilie F. Neubauer et al.   PeerJ

Mosquito C-type lectins maintain gut microbiome homeostasis

(2016) Xiaojing Pang et al.   Nature Microbiology

Probiotic Gut Microbiota Isolate Interacts with Dendritic Cells via Glycosylated Heterotrimeric Pili

(2016) Hanne L. P. Tytgat et al.   PLoS One

Comparative transcriptome analysis reveals insights into the streamlined genomes of haplosclerid demosponges

(2016) Christine Guzman et al.   Scientific Reports

Toll-like Receptor Signaling Promotes Development and Function of Sensory Neurons Required for a C. elegans Pathogen-Avoidance Behavior

(2015) Julia P. Brandt et al.   CURRENT BIOLOGY

Recent insights into structures and functions of C-type lectins in the immune system

(2015) Kurt Drickamer et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The surprisingly complex immune gene repertoire of a simple sponge, exemplified by the NLR genes: A capacity for specificity?

(2015) Sandie M. Degnan   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Scavenger receptor B protects shrimp from bacteria by enhancing phagocytosis and regulating expression of antimicrobial peptides

(2015) Wen-Jie Bi et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Diversity of animal immune receptors and the origins of recognition complexity in the deuterostomes

(2015) Katherine M. Buckley et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis

(2015) Y. L. Lightfoot et al.   EMBO JOURNAL

Outside-in signaling - a brief review of GPCR signaling with a focus on the Drosophila GPCR family

(2015) C. D. Hanlon et al.   JOURNAL OF CELL SCIENCE

High Innate Immune Specificity through Diversified C-Type Lectin-Like Domain Proteins in Invertebrates

(2015) Barbara Pees et al.   Journal of Innate Immunity

NOD-Like Receptors: Versatile Cytosolic Sentinels

(2015) Vinicius Motta et al.   PHYSIOLOGICAL REVIEWS

The genome ofAiptasia, a sea anemone model for coral symbiosis

(2015) Sebastian Baumgarten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling

(2015) A. M. P. Schieber et al.   SCIENCE

Scavenger Receptor Structure and Function in Health and Disease

(2015) Izma Zani et al.   Cells

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

(2014) Arunkumar Krishnan et al.   BMC EVOLUTIONARY BIOLOGY

Chemosensation of Bacterial Secondary Metabolites Modulates Neuroendocrine Signaling and Behavior of C. elegans

(2014) Joshua D. Meisel et al.   CELL

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

(2014) Laura M. Cox et al.   CELL

The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity

(2014) Alex de Mendoza et al.   Genome Biology and Evolution

A Shrimp C-type Lectin Inhibits Proliferation of the Hemolymph Microbiota by Maintaining the Expression of Antimicrobial Peptides

(2014) Xian-Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Analysis of Eight Transcriptomes from All Poriferan Classes Reveals Surprising Genetic Complexity in Sponges

(2014) Ana Riesgo et al.   MOLECULAR BIOLOGY AND EVOLUTION

Activation of a G protein–coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans

(2014) Olivier Zugasti et al.   NATURE IMMUNOLOGY

Enemy attraction: bacterial agonists for leukocyte chemotaxis receptors

(2014) Dominik Alexander Bloes et al.   NATURE REVIEWS MICROBIOLOGY

Role of the C-Type Lectin Receptors MCL and DCIR in Experimental Colitis

(2014) Julia Hütter et al.   PLoS One

Rethinking the role of immunity: lessons from Hydra

(2014) Thomas C.G. Bosch   TRENDS IN IMMUNOLOGY

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

(2014) N. A. Broderick et al.   mBio

Role of DUOX in gut inflammation: lessons from Drosophila model of gut-microbiota interactions

(2014) Sung-Hee Kim et al.   Frontiers in Cellular and Infection Microbiology

Fecal Microbiota Transplantation for Clostridium difficile Infection: Systematic Review and Meta-Analysis

(2013) Zain Kassam et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Bacterial-Derived Uracil as a Modulator of Mucosal Immunity and Gut-Microbe Homeostasis in Drosophila

(2013) Kyung-Ah Lee et al.   CELL

C-type Lectin Binds to β-Integrin to Promote Hemocytic Phagocytosis in an Invertebrate

(2013) Xian-Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

(2013) Aurélie Couturier-Maillard et al.   JOURNAL OF CLINICAL INVESTIGATION

The Characterization of Sponge NLRs Provides Insight into the Origin and Evolution of This Innate Immune Gene Family in Animals

(2013) Benedict Yuen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

(2013) A. Marijke Keestra et al.   NATURE

Innate immune recognition of the microbiota promotes host-microbial symbiosis

(2013) Hiutung Chu et al.   NATURE IMMUNOLOGY

Correction for Bencivenni et al., Direct asymmetric vinylogous Michael addition of cyclic enones to nitroalkenes via dienamine catalysis

(2013)   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct antimicrobial peptide expression determines host species-specific bacterial associations

(2013) S. Franzenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animals in a bacterial world, a new imperative for the life sciences

(2013) Margaret McFall-Ngai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive Differences in Gene Expression Between Symbiotic and Aposymbiotic Cnidarians

(2013) Erik M. Lehnert et al.   G3-Genes Genomes Genetics

Serotonergic Chemosensory Neurons Modify the C. elegans Immune Response by Regulating G-Protein Signaling in Epithelial Cells

(2013) Alexandra Anderson et al.   PLoS Pathogens

The C-Type Lectin Receptor SIGNR3 Binds to Fungi Present in Commensal Microbiota and Influences Immune Regulation in Experimental Colitis

(2013) Magdalena Eriksson et al.   Frontiers in Immunology

Debug Your Bugs – How NLRs Shape Intestinal Host-Microbe Interactions

(2013) Simone Lipinski et al.   Frontiers in Immunology

Outer Membrane Vesicles of a Human Commensal Mediate Immune Regulation and Disease Protection

(2012) Yue Shen et al.   Cell Host & Microbe

Peptidoglycan Sensing by the Receptor PGRP-LE in the Drosophila Gut Induces Immune Responses to Infectious Bacteria and Tolerance to Microbiota

(2012) Virginie Bosco-Drayon et al.   Cell Host & Microbe

Pathogen Sensing by Nucleotide-binding Oligomerization Domain-containing Protein 2 (NOD2) Is Mediated by Direct Binding to Muramyl Dipeptide and ATP

(2012) Jinyao Mo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice

(2012) Carles Ubeda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE

(2012) C. Neyen et al.   JOURNAL OF IMMUNOLOGY

The Complex NOD-Like Receptor Repertoire of the Coral Acropora digitifera Includes Novel Domain Combinations

(2012) Mayuko Hamada et al.   MOLECULAR BIOLOGY AND EVOLUTION

Knowing your friends: invertebrate innate immunity fosters beneficial bacterial symbioses

(2012) Spencer V. Nyholm et al.   NATURE REVIEWS MICROBIOLOGY

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

(2012) Arunkumar Krishnan et al.   PLoS One

MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers

(2012) S. Franzenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

Understanding the Role of Host Hemocytes in a Squid/Vibrio Symbiosis Using Transcriptomics and Proteomics

(2012) Andrew J. Collins et al.   Frontiers in Immunology

Feeding and the Rhodopsin Family G-Protein Coupled Receptors in Nematodes and Arthropods

(2012) João C.R. Cardoso et al.   Frontiers in Endocrinology

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Unusual Regulation of a STAT Protein by an SLC6 Family Transporter in C. elegans Epidermal Innate Immunity

(2011) Katja Dierking et al.   Cell Host & Microbe

Lactobacillus plantarum Promotes Drosophila Systemic Growth by Modulating Hormonal Signals through TOR-Dependent Nutrient Sensing

(2011) Gilles Storelli et al.   Cell Metabolism

Characterization of a scavenger receptor cysteine-rich-domain-containing protein of the starfish, Asterina pectinifera: ApSRCR1 acts as an opsonin in the larval and adult innate immune systems

(2011) Ryohei Furukawa et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Sequence variability of the pattern recognition receptor Mermaid mediates specificity of marine nematode symbioses

(2011) Silvia Bulgheresi et al.   ISME Journal

l-Ala-γ-d-Glu-meso-diaminopimelic Acid (DAP) Interacts Directly with Leucine-rich Region Domain of Nucleotide-binding Oligomerization Domain 1, Increasing Phosphorylation Activity of Receptor-interacting Serine/Threonine-protein Kinase 2 and Its Interaction with Nucleotide-binding Oligomerization Domain 1

(2011) Hamed Laroui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

NLR functions beyond pathogen recognition

(2011) Thomas A Kufer et al.   NATURE IMMUNOLOGY

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Metaorganisms as the new frontier

(2011) Thomas C.G. Bosch et al.   ZOOLOGY

Intestinal Bacteria and the Regulation of Immune Cell Homeostasis

(2010) David A. Hill et al.   Annual Review of Immunology

Peptidoglycan Recognition Proteins Protect Mice from Experimental Colitis by Promoting Normal Gut Flora and Preventing Induction of Interferon-γ

(2010) Sukumar Saha et al.   Cell Host & Microbe

Characterization and immune function of two intracellular sensors, HmTLR1 and HmNLR, in the injured CNS of an invertebrate

(2010) Virginie Cuvillier-Hot et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

A novel scavenger receptor-cysteine-rich (SRCR) domain containing scavenger receptor identified from mollusk mediated PAMP recognition and binding

(2010) Lin Liu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The genome of the sponge Amphimedon queenslandica provides new perspectives into the origin of Toll-like and interleukin 1 receptor pathways

(2010) Marie E. A. Gauthier et al.   EVOLUTION & DEVELOPMENT

Review: Mammalian peptidoglycan recognition proteins (PGRPs) in innate immunity

(2010) Roman Dziarski et al.   Innate Immunity

Endogenous toll-like receptor ligands and their biological significance

(2010) Li Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Defining the Origins of the NOD-Like Receptor System at the Base of Animal Evolution

(2010) C. Lange et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Amphimedon queenslandica genome and the evolution of animal complexity

(2010) Mansi Srivastava et al.   NATURE

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Proteomic analysis of symbiosome membranes in Cnidaria-dinoflagellate endosymbiosis

(2010) Shao-En Peng et al.   PROTEOMICS

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Antifungal Innate Immunity in C. elegans: PKCδ Links G Protein Signaling and a Conserved p38 MAPK Cascade

(2009) Katja Ziegler et al.   Cell Host & Microbe

Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis

(2009) Joshua V. Troll et al.   CELLULAR MICROBIOLOGY

Regulation of DUOX by the Gαq-Phospholipase Cβ-Ca2+ Pathway in Drosophila Gut Immunity

(2009) Eun-Mi Ha et al.   DEVELOPMENTAL CELL

Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin

(2009) Joshua V. Troll et al.   ENVIRONMENTAL MICROBIOLOGY

Evolution and Function of Innate Immune Receptors – Insights from Marine Invertebrates

(2009) Philip Rosenstiel et al.   Journal of Innate Immunity

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

A Polymorphism in npr-1 Is a Behavioral Determinant of Pathogen Susceptibility in C. elegans

(2009) K. C. Reddy et al.   SCIENCE

PIMS Modulates Immune Tolerance by Negatively Regulating Drosophila Innate Immune Signaling

(2008) Nouara Lhocine et al.   Cell Host & Microbe

Distinct Innate Immune Responses to Infection and Wounding in the C. elegans Epidermis

(2008) Nathalie Pujol et al.   CURRENT BIOLOGY

Uncovering the evolutionary history of innate immunity: The simple metazoan Hydra uses epithelial cells for host defence

(2008) Thomas C.G. Bosch et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions

(2008) S. R. Konstantinov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immunity in Caenorhabditis elegans Is Regulated by Neurons Expressing NPR-1/GPCR

(2008) K. L. Styer et al.   SCIENCE

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

(2008) J.-H. Ryu et al.   SCIENCE