ERK signalling: a master regulator of cell behaviour, life and fate
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Title
ERK signalling: a master regulator of cell behaviour, life and fate
Authors
Keywords
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Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-06-23
DOI
10.1038/s41580-020-0255-7
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Note: Only part of the references are listed.- EGFR activates GDH1 transcription to promote glutamine metabolism through MEK/ERK/ELK1 pathway in glioblastoma
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- (2019) Rumani Singh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2019) Lucía García-Gutiérrez et al. Genes
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- (2019) Shiela C. Samson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic lineage priming is driven via direct enhancer regulation by ERK
- (2019) William B. Hamilton et al. NATURE
- Strategies for Engineering and Rewiring Kinase Regulation
- (2019) James W. McCormick et al. TRENDS IN BIOCHEMICAL SCIENCES
- BCL-2 proteins and apoptosis: Recent insights and unknowns
- (2018) Frank Edlich BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma
- (2018) Thibault Houles et al. CANCER RESEARCH
- MAPK and PI3K signaling: At the crossroads of neural crest development
- (2018) Colin J. Dinsmore et al. DEVELOPMENTAL BIOLOGY
- The EGF/Ras pathway controls growth in Drosophila via ribosomal RNA synthesis
- (2018) Shrivani Sriskanthadevan-Pirahas et al. DEVELOPMENTAL BIOLOGY
- Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates cardiomyocyte identity
- (2018) Tatjana Dorn et al. EMBO JOURNAL
- Negative feedback via RSK modulates Erk‐dependent progression from naïve pluripotency
- (2018) Isabelle RE Nett et al. EMBO REPORTS
- ERF deletion rescues RAS deficiency in mouse embryonic stem cells
- (2018) Cristina Mayor-Ruiz et al. GENES & DEVELOPMENT
- MEK drives BRAF activation through allosteric control of KSR proteins
- (2018) Hugo Lavoie et al. NATURE
- Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma
- (2018) Qiumin Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E
- (2018) Argel Aguilar-Valles et al. Nature Communications
- Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila
- (2018) Shrivani Sriskanthadevan-Pirahas et al. PLoS Genetics
- KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency
- (2018) Navroop K. Dhaliwal et al. Stem Cell Reports
- Four Key Steps Control Glycolytic Flux in Mammalian Cells
- (2018) Lukas Bahati Tanner et al. Cell Systems
- Outstanding questions in developmental ERK signaling
- (2018) Aleena L. Patel et al. DEVELOPMENT
- Ewing-like sarcoma: An emerging family of round cell sarcomas
- (2018) Samuele Renzi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway
- (2018) L. J. Bugaj et al. SCIENCE
- Ras signals principally via Erk in G1 but cooperates with PI3K/Akt for Cyclin D induction and S-phase entry
- (2018) Ledia Vasjari et al. CELL CYCLE
- Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis
- (2018) Naiara Santana-Codina et al. Nature Communications
- A compendium of ERK targets
- (2017) Evrim B. Ünal et al. FEBS LETTERS
- ERK signalling as a regulator of cell motility
- (2017) Susumu Tanimura et al. JOURNAL OF BIOCHEMISTRY
- Rho GTPase signaling complexes in cell migration and invasion
- (2017) Campbell D. Lawson et al. JOURNAL OF CELL BIOLOGY
- Time-resolved Phosphoproteome Analysis of Paradoxical RAF Activation Reveals Novel Targets of ERK
- (2017) Peter Kubiniok et al. MOLECULAR & CELLULAR PROTEOMICS
- ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription
- (2017) Cyril Esnault et al. MOLECULAR CELL
- ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis
- (2017) Rohit Bose et al. NATURE
- Competing memories of mitogen and p53 signalling control cell-cycle entry
- (2017) Hee Won Yang et al. NATURE
- Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans
- (2017) Hsiang-Chih Lu et al. NATURE GENETICS
- Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis
- (2017) Rodrigo Romero et al. NATURE MEDICINE
- AMPK: guardian of metabolism and mitochondrial homeostasis
- (2017) Sébastien Herzig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Local destabilization, rigid body, and fuzzy docking facilitate the phosphorylation of the transcription factor Ets-1 by the mitogen-activated protein kinase ERK2
- (2017) Andrea Piserchio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases
- (2017) Geng-Xian Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome
- (2017) Jiani C. Yin et al. Nature Communications
- Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction
- (2016) John J.M. Bergeron et al. Annual Review of Biochemistry
- Plasticity of Cell Migration In Vivo and In Silico
- (2016) Veronika te Boekhorst et al. Annual Review of Cell and Developmental Biology
- Negative feedback regulation of the ERK1/2 MAPK pathway
- (2016) David Lake et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- PKM2, cancer metabolism, and the road ahead
- (2016) Talya L Dayton et al. EMBO REPORTS
- ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips
- (2016) Susumu Tanimura et al. JOURNAL OF CELL BIOLOGY
- Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines
- (2016) Jessica Lauriol et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulatory roles of conserved phosphorylation sites in the activation T-loop of the MAP kinase ERK1
- (2016) Shenshen Lai et al. MOLECULAR BIOLOGY OF THE CELL
- SRF Co-factors Control the Balance between Cell Proliferation and Contractility
- (2016) Francesco Gualdrini et al. MOLECULAR CELL
- Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities
- (2016) Emma M. Kerr et al. NATURE
- A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
- (2016) Chi Luo et al. NATURE
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- (2016) A. Mylona et al. SCIENCE
- Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
- (2016) Javier Prieto et al. Nature Communications
- Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells
- (2016) Bradley Smith et al. Cell Reports
- Phosphorylation acts positively and negatively to regulate MRTF-A subcellular localisation and activity
- (2016) Richard Panayiotou et al. eLife
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- (2015) Ana Herrero et al. CANCER CELL
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- (2015) J. Pelletier et al. CANCER RESEARCH
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- (2015) Vijay Padul et al. GENES CHROMOSOMES & CANCER
- Vemurafenib resistance reprograms melanoma cells towards glutamine dependence
- (2015) Jenny E Hernandez-Davies et al. Journal of Translational Medicine
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- (2015) N. Theodosakis et al. MOLECULAR CANCER THERAPEUTICS
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- (2015) Madhavika N. Serasinghe et al. MOLECULAR CELL
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- (2015) Jennifer A. Kashatus et al. MOLECULAR CELL
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- (2015) Claudia Wellbrock et al. Pigment Cell & Melanoma Research
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- (2015) Haixia Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On being the right (cell) size
- (2015) M. B. Ginzberg et al. SCIENCE
- ERK reinforces actin polymerization to power persistent edge protrusion during motility
- (2015) Michelle C. Mendoza et al. Science Signaling
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- (2015) Romaric Bouveret et al. eLife
- Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
- (2015) Toru Hiratsuka et al. eLife
- ERK reinforces actin polymerization to power persistent edge protrusion during motility
- (2015) Michelle C. Mendoza et al. Science Signaling
- Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene
- (2015) Arnaldur Hall et al. Oncotarget
- The Nature of Embryonic Stem Cells
- (2014) Graziano Martello et al. Annual Review of Cell and Developmental Biology
- ERKs in Cancer: Friends or Foes?
- (2014) Xavier Deschênes-Simard et al. CANCER RESEARCH
- Erk1/2 Activity Promotes Chromatin Features and RNAPII Phosphorylation at Developmental Promoters in Mouse ESCs
- (2014) Wee-Wei Tee et al. CELL
- Klf2 Is an Essential Factor that Sustains Ground State Pluripotency
- (2014) Jia-Chi Yeo et al. Cell Stem Cell
- SRF Regulates Craniofacial Development through Selective Recruitment of MRTF Cofactors by PDGF Signaling
- (2014) Harish N. Vasudevan et al. DEVELOPMENTAL CELL
- The core and conserved role of MAL is homeostatic regulation of actin levels
- (2014) L. Salvany et al. GENES & DEVELOPMENT
- Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts
- (2014) C. Esnault et al. GENES & DEVELOPMENT
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- Metabolic requirements for the maintenance of self-renewing stem cells
- (2014) Keisuke Ito et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cardio-Facio-Cutaneous Syndrome: Clinical Features, Diagnosis, and Management Guidelines
- (2014) M. E. M. Pierpont et al. PEDIATRICS
- MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by 1-adrenergic receptors
- (2014) T. Ogata et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3
- (2014) J. A. Galan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis
- (2014) T. J. Parmenter et al. Cancer Discovery
- Two-Stage Translational Control of Dentate Gyrus LTP Consolidation Is Mediated by Sustained BDNF-TrkB Signaling to MNK
- (2014) Debabrata Panja et al. Cell Reports
- NANOG Is Multiply Phosphorylated and Directly Modified by ERK2 and CDK1 In Vitro
- (2014) Justin Brumbaugh et al. Stem Cell Reports
- The RASopathies
- (2013) Katherine A. Rauen Annual Review of Genomics and Human Genetics
- PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
- (2013) Francisca Vazquez et al. CANCER CELL
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- MEK1/2 Inhibition Decreases Lactate in BRAF-Driven Human Cancer Cells
- (2013) Maria Falck Miniotis et al. CANCER RESEARCH
- BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
- (2013) D. T. Frederick et al. CLINICAL CANCER RESEARCH
- Deletion ofMAP2K2/MEK2: a novel mechanism for a RASopathy?
- (2013) M.J.M. Nowaczyk et al. CLINICAL GENETICS
- Genome-wide Kinase-Chromatin Interactions Reveal the Regulatory Network of ERK Signaling in Human Embryonic Stem Cells
- (2013) Jonathan Göke et al. MOLECULAR CELL
- Phosphorylation of BRAF by AMPK Impairs BRAF-KSR1 Association and Cell Proliferation
- (2013) Che-Hung Shen et al. MOLECULAR CELL
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis
- (2013) Stephen R F Twigg et al. NATURE GENETICS
- Control of cell cycle transcription during G1 and S phases
- (2013) Cosetta Bertoli et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Ras-ERK pathway modulates cytoskeleton organization, cell motility and lung metastasis signature genes in MDA-MB-231 LM2
- (2013) C Choi et al. ONCOGENE
- ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer
- (2013) Q Ye et al. ONCOGENE
- Interference with ERKThr188 phosphorylation impairs pathological but not physiological cardiac hypertrophy
- (2013) C. Ruppert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular basis of MAP kinase regulation
- (2013) Wolfgang Peti et al. PROTEIN SCIENCE
- STAT3 Phosphorylation at Tyrosine 705 and Serine 727 Differentially Regulates Mouse ESC Fates
- (2013) Guanyi Huang et al. STEM CELLS
- Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK
- (2013) Peter D. Mace et al. Nature Communications
- ERK Inhibition Rescues Defects in Fate Specification of Nf1-Deficient Neural Progenitors and Brain Abnormalities
- (2012) Yuan Wang et al. CELL
- MYC on the Path to Cancer
- (2012) Chi V. Dang CELL
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik
- (2012) J Lopez et al. CELL DEATH AND DIFFERENTIATION
- BMP4 Signaling Acts via Dual-Specificity Phosphatase 9 to Control ERK Activity in Mouse Embryonic Stem Cells
- (2012) Zhongwei Li et al. Cell Stem Cell
- Serine 111 Phosphorylation Regulates OCT4A Protein Subcellular Distribution and Degradation
- (2012) Renza Spelat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PGC1 and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders
- (2012) S. Austin et al. JOURNAL OF CELL SCIENCE
- Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals
- (2012) John G. Albeck et al. MOLECULAR CELL
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4
- (2012) Myoung Ok Kim et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity
- (2012) Y Shao et al. Cell Death & Disease
- Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors
- (2011) Peter C. Hollenhorst et al. Annual Review of Biochemistry
- Solution NMR Insights into Docking Interactions Involving Inactive ERK2
- (2011) Andrea Piserchio et al. BIOCHEMISTRY
- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
- (2011) J. Schodel et al. BLOOD
- FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
- (2011) Jennifer C. Darnell et al. CELL
- Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells
- (2011) P. C. Hollenhorst et al. GENES & DEVELOPMENT
- Comparative Metabolic Flux Profiling of Melanoma Cell Lines
- (2011) David A. Scott et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
- (2011) M. Cargnello et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
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- (2011) Yaara Zwang et al. MOLECULAR CELL
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- (2011) Michelle C. Mendoza et al. MOLECULAR CELL
- Regulation of Primary Response Genes
- (2011) Trent Fowler et al. MOLECULAR CELL
- Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
- (2011) D. Gaglio et al. Molecular Systems Biology
- The transcriptional and signalling networks of pluripotency
- (2011) Huck-Hui Ng et al. NATURE CELL BIOLOGY
- Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo
- (2011) J. H. van Berlo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma
- (2011) C. Bettegowda et al. SCIENCE
- MED23 Mutation Links Intellectual Disability to Dysregulation of Immediate Early Gene Expression
- (2011) S. Hashimoto et al. SCIENCE
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- (2011) Ian A. Prior et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Converging on the function of intrinsically disordered nucleoporins in the nuclear pore complex
- (2010) Orit Peleg et al. BIOLOGICAL CHEMISTRY
- Ligand-Specific c-Fos Expression Emerges from the Spatiotemporal Control of ErbB Network Dynamics
- (2010) Takashi Nakakuki et al. CELL
- Molecular mechanisms of cranial neural crest cell migration and patterning in craniofacial development
- (2010) M. Minoux et al. DEVELOPMENT
- Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival
- (2010) Matthias Drosten et al. EMBO JOURNAL
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- (2010) Audrey Carriere et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Extracellular Signal-Regulated Kinase Promotes Rho-Dependent Focal Adhesion Formation by Suppressing p190A RhoGAP
- (2010) A. K. Pullikuth et al. MOLECULAR AND CELLULAR BIOLOGY
- Genetic Demonstration of a Redundant Role of Extracellular Signal-Regulated Kinase 1 (ERK1) and ERK2 Mitogen-Activated Protein Kinases in Promoting Fibroblast Proliferation
- (2010) L. Voisin et al. MOLECULAR AND CELLULAR BIOLOGY
- Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
- (2010) Xonia Carvajal-Vergara et al. NATURE
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- (2010) J. Thomas Parsons et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2010) Eric N. Olson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2010) Gretchen Poortinga et al. NUCLEIC ACIDS RESEARCH
- Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
- (2010) T. Ueda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2010) L. Furic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2010) Susan S. Taylor et al. TRENDS IN BIOCHEMICAL SCIENCES
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- (2009) Shaohui Hu et al. CELL
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- (2009) Matthew Good et al. CELL
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- (2009) Chunxi Ge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) C. Y. Hwang et al. MOLECULAR AND CELLULAR BIOLOGY
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- (2009) Yanhua Zheng et al. MOLECULAR CELL
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- (2009) Jeremy P. Clark et al. Nature Reviews Urology
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- (2009) T. Nakamura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) Shuh-hei Fujishiro et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2007) R. Matthew Klein et al. MOLECULAR BIOLOGY OF THE CELL
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