Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Specificity of Linear Motifs That Bind to a Common Mitogen-Activated Protein Kinase Docking Groove

(2012) A. Garai et al.   Science Signaling

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Examining Docking Interactions on ERK2 with Modular Peptide Substrates

(2011) Sunbae Lee et al.   BIOCHEMISTRY

ERK dimers and scaffold proteins: Unexpected partners for a forgotten (cytoplasmic) task

(2011) Berta Casar et al.   CELL CYCLE

PEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastoma

(2011) Joanna E. Gawecka et al.   INTERNATIONAL JOURNAL OF CANCER

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK

(2011) Damian F. Brennan et al.   NATURE

PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D

(2011) F J Sulzmaier et al.   ONCOGENE

Three-Dimensional Docking in the MAPK p38 

(2011) E. J. Goldsmith   Science Signaling

Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3

(2011) S. M. Carlson et al.   Science Signaling

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PEA-15 Inhibits Tumorigenesis in an MDA-MB-468 Triple-Negative Breast Cancer Xenograft Model through Increased Cytoplasmic Localization of Activated Extracellular Signal-Regulated Kinase

(2010) C. Bartholomeusz et al.   CLINICAL CANCER RESEARCH

Expression of phosphoprotein enriched in astrocytes 15 kDa (PEA-15) in astrocytic tumors: a novel approach of correlating malignancy grade and prognosis

(2010) Yosuke Watanabe et al.   JOURNAL OF NEURO-ONCOLOGY

Phosphorylation of DCC by ERK2 Is Facilitated by Direct Docking of the Receptor P1 Domain to the Kinase

(2010) Wenfu Ma et al.   STRUCTURE

Cell fate decisions are specified by the dynamic ERK interactome

(2009) Alex von Kriegsheim et al.   NATURE CELL BIOLOGY

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport

(2009) Hidetaka Kosako et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Substrate Discrimination among Mitogen-activated Protein Kinases through Distinct Docking Sequence Motifs

(2008) Douglas L. Sheridan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospho-ERK Staining Is a Poor Indicator of the Mutational Status of BRAF and NRAS in Human Melanoma

(2008) Roland Houben et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Essential Role of ERK Dimers in the Activation of Cytoplasmic but Not Nuclear Substrates by ERK-Scaffold Complexes

(2008) Berta Casar et al.   MOLECULAR CELL

Unique MAP Kinase binding sites

(2007) Radha Akella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS