Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila
Authors
Keywords
Transfer RNA, Drosophila melanogaster, Ras signaling, RNA interference, Gastrointestinal tract, Larvae, RNA isolation, Phosphorylation
Journal
PLoS Genetics
Volume 14, Issue 2, Pages e1007202
Publisher
Public Library of Science (PLoS)
Online
2018-02-06
DOI
10.1371/journal.pgen.1007202
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Investigation of protein synthesis inDrosophilalarvae using puromycin labelling
- (2017) Lisa P. Deliu et al. Biology Open
- Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression
- (2016) Hani Goodarzi et al. CELL
- The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis
- (2016) Cassie J. Clarke et al. CURRENT BIOLOGY
- The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma
- (2016) Joanna Birch et al. Biology Open
- Why should cancer biologists care about tRNAs? tRNA synthesis, mRNA translation and the control of growth
- (2015) Savraj S. Grewal Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- The Levels of a Universally Conserved tRNA Modification Regulate Cell Growth
- (2015) Diego Rojas-Benitez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes
- (2015) Yinhua Jin et al. PLoS Genetics
- A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation
- (2014) Hila Gingold et al. CELL
- A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila
- (2014) Dariel Ashton-Beaucage et al. PLOS BIOLOGY
- The RASopathies
- (2013) Katherine A. Rauen Annual Review of Genomics and Human Genetics
- mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation
- (2013) Masahiro Morita et al. Cell Metabolism
- Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration
- (2013) Fangfang Ren et al. CELL RESEARCH
- Regulation of Hippo Signaling by EGFR-MAPK Signaling through Ajuba Family Proteins
- (2013) B.V.V.G. Reddy et al. DEVELOPMENTAL CELL
- Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice
- (2013) L. Soucek et al. GENES & DEVELOPMENT
- Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells
- (2013) M. Pavon-Eternod et al. RNA
- Mutual Repression by Bantam miRNA and Capicua Links the EGFR/MAPK and Hippo Pathways in Growth Control
- (2012) Héctor Herranz et al. CURRENT BIOLOGY
- Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut
- (2012) J. B. Cordero et al. DEVELOPMENT
- Nutrient/TOR-dependent regulation of RNA polymerase III controls tissue and organismal growth inDrosophila
- (2012) Lynne Marshall et al. EMBO JOURNAL
- PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression
- (2012) Andrew J Oler et al. EMBO JOURNAL
- Oncogenic cooperation between SOCS family proteins and EGFR identified using a Drosophila epithelial transformation model
- (2012) H. Herranz et al. GENES & DEVELOPMENT
- A unifying model for mTORC1-mediated regulation of mRNA translation
- (2012) Carson C. Thoreen et al. NATURE
- The translational landscape of mTOR signalling steers cancer initiation and metastasis
- (2012) Andrew C. Hsieh et al. NATURE
- RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth
- (2012) Y Romeo et al. ONCOGENE
- Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling
- (2012) E. J. Rideout et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection
- (2011) Nicolas Buchon et al. BMC BIOLOGY
- EGF signaling regulates the proliferation of intestinal stem cells in Drosophila
- (2011) B. Biteau et al. DEVELOPMENT
- EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells
- (2011) Na Xu et al. DEVELOPMENTAL BIOLOGY
- EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila
- (2010) Huaqi Jiang et al. Cell Stem Cell
- Paving the way for targeting RSK in cancer
- (2010) Yves Romeo et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells
- (2010) Boris Shor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- mTORC1 Directly Phosphorylates and Regulates Human MAF1
- (2010) A. A. Michels et al. MOLECULAR AND CELLULAR BIOLOGY
- Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
- (2010) T. Ueda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1
- (2010) T. Kantidakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
- (2010) R. J. O. Dowling et al. SCIENCE
- High levels of tRNA abundance and alteration of tRNA charging by bortezomib in multiple myeloma
- (2009) Ying Zhou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors
- (2009) H. Jiang et al. DEVELOPMENT
- Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1
- (2009) Yuehua Wei et al. EMBO JOURNAL
- Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis
- (2009) A. Huber et al. GENES & DEVELOPMENT
- tRNA over-expression in breast cancer and functional consequences
- (2009) Mariana Pavon-Eternod et al. NUCLEIC ACIDS RESEARCH
- Dynamic Control of Cell Cycle and Growth Coupling by Ecdysone, EGFR, and PI3K Signaling in Drosophila Histoblasts
- (2009) Nikolay Ninov et al. PLOS BIOLOGY
- A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma
- (2009) Renee D. Read et al. PLoS Genetics
- Max-independent functions of Myc in Drosophila melanogaster
- (2008) Dominik Steiger et al. NATURE GENETICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More