Ras signals principally via Erk in G1 but cooperates with PI3K/Akt for Cyclin D induction and S-phase entry

Cell confluence induces switching from proliferation to migratory signaling by site-selective phosphorylation of PDGF receptors on lipid raft platforms

(2016) Árpád Szöőr et al.   CELLULAR SIGNALLING

Rapamycin-induced oligomer formation system of FRB–FKBP fusion proteins

(2016) Tomonao Inobe et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Inhibition of RAS function through targeting an allosteric regulatory site

(2016) Russell Spencer-Smith et al.   Nature Chemical Biology

PI3K signalling in inflammation

(2015) P.T. Hawkins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras

(2015) Agnès Desroches-Castan et al.   Oncotarget

KRas Localizes to the Plasma Membrane by Spatial Cycles of Solubilization, Trapping and Vesicular Transport

(2014) Malte Schmick et al.   CELL

Graded inhibition of oncogenic Ras-signaling by multivalent Ras-binding domains

(2014) Martin Augsten et al.   Cell Communication and Signaling

RAS interaction with PI3K p110α is required for tumor-induced angiogenesis

(2014) Miguel Manuel Murillo et al.   JOURNAL OF CLINICAL INVESTIGATION

PP2A-Mediated Regulation of Ras Signaling in G2 Is Essential for Stable Quiescence and Normal G1 Length

(2014) Nana Naetar et al.   MOLECULAR CELL

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

(2014) Pengda Liu et al.   NATURE

Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling

(2013) Shu-Ping Song et al.   BIOCHEMICAL JOURNAL

Killing Tumors by Keeping Ras and PI3′ Kinase Apart

(2013) Tina L. Yuan et al.   CANCER CELL

Requirement for Interaction of PI3-Kinase p110α with RAS in Lung Tumor Maintenance

(2013) Esther Castellano et al.   CANCER CELL

RAS and RHO Families of GTPases Directly Regulate Distinct Phosphoinositide 3-Kinase Isoforms

(2013) Ralph Fritsch et al.   CELL

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

Protein translocation as a tool: The current rapamycin story

(2012) Mateusz Putyrski et al.   FEBS LETTERS

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

(2010) Matthias Drosten et al.   EMBO JOURNAL

TCR-Induced Activation of Ras Proceeds at the Plasma Membrane and Requires Palmitoylation of N-Ras

(2010) I. Rubio et al.   JOURNAL OF IMMUNOLOGY

Genetic and cell biological analysis of integrin outside-in signaling

(2009) K. R. Legate et al.   GENES & DEVELOPMENT

Heregulin β1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1

(2008) Chengfeng Yang et al.   BIOCHEMICAL JOURNAL

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY