Molecular basis of MAP kinase regulation

Dual-specificity phosphatases: critical regulators with diverse cellular targets

(2015) Kate I. Patterson et al.   BIOCHEMICAL JOURNAL

The Quiet Renaissance of Protein Nuclear Magnetic Resonance

(2013) Paul J. Barrett et al.   BIOCHEMISTRY

Sequence-specific backbone 1H, 13C and 15N assignments of the 34 kDa catalytic domain of PTPN5 (STEP)

(2013) Dana M. Francis et al.   Biomolecular NMR Assignments

Structural Basis for the Regulation of the Mitogen-activated Protein (MAP) Kinase p38α by the Dual Specificity Phosphatase 16 MAP Kinase Binding Domain in Solution

(2013) Ganesan Senthil Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Mechanism for the Specific Assembly and Activation of the Extracellular Signal Regulated Kinase 5 (ERK5) Module

(2013) Gábor Glatz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the p38α MAP kinase in complex with a docking peptide from TAB1

(2013) FengJiao Xin et al.   Science China-Life Sciences

The Differential Regulation of p38α by the Neuronal Kinase Interaction Motif Protein Tyrosine Phosphatases, a Detailed Molecular Study

(2013) Dana May Francis et al.   STRUCTURE

Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK

(2013) Peter D. Mace et al.   Nature Communications

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

(2013) Simina Grigoriu et al.   PLOS BIOLOGY

Docking Interactions of Hematopoietic Tyrosine Phosphatase with MAP Kinases ERK2 and p38α

(2012) Andrea Piserchio et al.   BIOCHEMISTRY

Dual-specificity MAP kinase phosphatases (MKPs)

(2012) Christopher J. Caunt et al.   FEBS Journal

A CC-SAM, for Coiled Coil-Sterile   Motif, Domain Targets the Scaffold KSR-1 to Specific Sites in the Plasma Membrane

(2012) D. Koveal et al.   Science Signaling

Specificity of Linear Motifs That Bind to a Common Mitogen-Activated Protein Kinase Docking Groove

(2012) A. Garai et al.   Science Signaling

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases

(2012) John D. Laughlin et al.   STRUCTURE

The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme

(2012) Nichole O'Connell et al.   STRUCTURE

DUSPs, to MAP kinases and beyond

(2012) Ching-Yu Huang et al.   Cell and Bioscience

Solution NMR Insights into Docking Interactions Involving Inactive ERK2

(2011) Andrea Piserchio et al.   BIOCHEMISTRY

NMR Spectroscopic Investigations of the Activated p38α Mitogen-Activated Protein Kinase

(2011) Gerd Nielsen et al.   CHEMBIOCHEM

Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38α

(2011) Yuan-Yuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resting and Active States of the ERK2:HePTP Complex

(2011) Dana M. Francis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis of p38α regulation by hematopoietic tyrosine phosphatase

(2011) Dana M Francis et al.   Nature Chemical Biology

A Model of a MAPK•Substrate Complex in an Active Conformation: A Computational and Experimental Approach

(2011) Sunbae Lee et al.   PLoS One

A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38  with the MAPK Binding Domain of the Phosphatase MKP5

(2011) Y.-Y. Zhang et al.   Science Signaling

SAXS Ensemble Refinement of ESCRT-III CHMP3 Conformational Transitions

(2011) Bartosz Różycki et al.   STRUCTURE

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Phosphorylation of the Transcription Factor Ets-1 by ERK2: Rapid Dissociation of ADP and Phospho-Ets-1

(2010) Kari Callaway et al.   BIOCHEMISTRY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

(2010) Michael J Ragusa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phosphorylation of DCC by ERK2 Is Facilitated by Direct Docking of the Receptor P1 Domain to the Kinase

(2010) Wenfu Ma et al.   STRUCTURE

The Third Conformation of p38α MAP Kinase Observed in Phosphorylated p38α and in Solution

(2010) Radha Akella et al.   STRUCTURE

Selectivity of Docking Sites in MAPK Kinases

(2009) A. Jane Bardwell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling dynamics of the KSR1 scaffold complex

(2009) M. M. McKay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

Dynamics in the p38α MAP Kinase–SB203580 Complex Observed by Liquid-State NMR Spectroscopy

(2008) Valerie S. Honndorf et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Basis of Substrate Recognition by Hematopoietic Tyrosine Phosphatase†,‡

(2008) David A. Critton et al.   BIOCHEMISTRY

Sequence-specific 1H, 13C and 15N backbone resonance assignments of the 34 kDa catalytic domain of human PTPN7

(2008) Mark Jeeves et al.   Biomolecular NMR Assignments

Protein scaffolds in MAP kinase signalling

(2008) Matthew D. Brown et al.   CELLULAR SIGNALLING