β-Glucan–induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

(2019) Yang Yang et al.   Cell Death & Disease

Trained Innate Immunity Not Always Amicable

(2019) Włodarczyk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection

(2019) Ignacio Santecchia et al.   PLoS Pathogens

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32

(2019) Jéssica Cristina dos Santos et al.   Cell Reports

Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome

(2018) Haipeng Yin et al.   JOURNAL OF IMMUNOLOGY

Remembering Pathogen Dose: Long-Term Adaptation in Innate Immunity

(2018) Michael Bauer et al.   TRENDS IN IMMUNOLOGY

The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders

(2018) Rob J. W. Arts et al.   Frontiers in Immunology

Targeting Macrophages in Cancer: From Bench to Bedside

(2018) Ashleigh R. Poh et al.   Frontiers in Oncology

Consensus proposal for taxonomy and definition of the autoinflammatory diseases (AIDs): a Delphi study

(2018) Eldad Ben-Chetrit et al.   ANNALS OF THE RHEUMATIC DISEASES

The classification, genetic diagnosis and modelling of monogenic autoinflammatory disorders

(2018) Fiona Moghaddas et al.   CLINICAL SCIENCE

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

(2018) Zhenyu Zhong et al.   NATURE

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

(2018) Silvia Sánchez-Ramón et al.   Frontiers in Immunology

Different dynamics of NLRP3 inflammasome-mediated IL‑1β production in GM-CSF– and M-CSF–differentiated human macrophages

(2017) Marietta Margit Budai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

M1 and M2 macrophages’ clinicopathological significance in cutaneous melanoma

(2017) Monica Falleni et al.   MELANOMA RESEARCH

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Effect of Dietary Beta-Glucan on the Performance of Broilers and the Quality of Broiler Breast Meat

(2016) Sun Hee Moon et al.   ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Metabolism

Post-translational regulation of inflammasomes

(2016) Jie Yang et al.   Cellular & Molecular Immunology

In VitroExperimental Model of Trained Innate Immunity in Human Primary Monocytes

(2016) Siroon Bekkering et al.   Clinical and Vaccine Immunology

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

The Cost Of Illness of Ultra-Rare Cryopyrin Associated Periodic Syndromes (CAPS) In Italy: Preliminary Results From The Radicea Project

(2016) V Lorenzoni et al.   VALUE IN HEALTH

The Inflammasomes and Autoinflammatory Syndromes

(2015) Lori Broderick et al.   Annual Review of Pathology-Mechanisms of Disease

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease

(2015) Yun-Hee Youm et al.   NATURE MEDICINE

Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance

(2015) Sonia Carta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

K+ regulates Ca2+ to drive inflammasome signaling: dynamic visualization of ion flux in live cells

(2015) J R Yaron et al.   Cell Death & Disease

Innate Immune Memory: The Latest Frontier of Adjuvanticity

(2015) Elfi Töpfer et al.   Journal of Immunology Research

Mechanism of NLRP3 inflammasome activation

(2014) Fayyaz S. Sutterwala et al.   Annals of the New York Academy of Sciences

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes

(2014) P. Gurung et al.   JOURNAL OF IMMUNOLOGY

The Effects of Orally Administered Beta-Glucan on Innate Immune Responses in Humans, a Randomized Open-Label Intervention Pilot-Study

(2014) Jenneke Leentjens et al.   PLoS One

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

(2013) Takuma Misawa et al.   NATURE IMMUNOLOGY

Computational classification of mitochondrial shapes reflects stress and redox state

(2013) T Ahmad et al.   Cell Death & Disease

Canakinumab in patients with cryopyrin-associated periodic syndrome: an update for clinicians

(2013) Jasmin B. Kuemmerle-Deschner et al.   Therapeutic Advances in Musculoskeletal Disease

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

(2012) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

(2011) Yukiji Takeda et al.   NATURE

Role of the Inflammasome, IL-1β, and IL-18 in Bacterial Infections

(2011) Manoranjan Sahoo et al.   TheScientificWorldJOURNAL

Statin Attenuates Experimental Anti-Glomerular Basement Membrane Glomerulonephritis Together with the Augmentation of Alternatively Activated Macrophages

(2010) Emiko Fujita et al.   AMERICAN JOURNAL OF PATHOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1  secretion

(2010) S. Tassi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease

(2009) Seth L. Masters et al.   Annual Review of Immunology

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD