Canakinumab in patients with cryopyrin-associated periodic syndrome: an update for clinicians

The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age

(2013) Roberta Caorsi et al.   ARTHRITIS RESEARCH & THERAPY

Eradication ofHelicobacter pylorireduce disease activity and severity in systemic sclerosis

(2012) Mislav Radić et al.   ANNALS OF THE RHEUMATIC DISEASES

Hearing loss in Muckle-Wells syndrome

(2012) Jasmin B. Kuemmerle-Deschner et al.   ARTHRITIS AND RHEUMATISM

MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes

(2011) H. Wittkowski et al.   ANNALS OF THE RHEUMATIC DISEASES

Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrin-associated periodic syndrome across different severity phenotypes

(2011) J. B. Kuemmerle-Deschner et al.   ANNALS OF THE RHEUMATIC DISEASES

High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: Results of an international multicenter collaborative study

(2011) Naoko Tanaka et al.   ARTHRITIS AND RHEUMATISM

Identification of a genetically diverse sequence of porcine reproductive and respiratory syndrome virus in Slovenia and the impact on the sensitivity of four molecular tests

(2011) I. Toplak et al.   JOURNAL OF VIROLOGICAL METHODS

Cryopyrin-Associated Periodic Syndromes

(2011) Neda Ahmadi et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

NLRP3 E311K mutation in a large family with Muckle-Wells syndrome - description of a heterogeneous phenotype and response to treatment

(2011) Jasmin B Kuemmerle-Deschner et al.   ARTHRITIS RESEARCH & THERAPY

Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study

(2011) Isabelle Koné-Paut et al.   ARTHRITIS RESEARCH & THERAPY

Current Status of Understanding the Pathogenesis and Management of Patients With NOMID/CINCA

(2011) Raphaela Goldbach-Mansky   Current Rheumatology Reports

A preliminary score for the assessment of disease activity in hereditary recurrent fevers: results from the AIDAI (Auto-Inflammatory Diseases Activity Index) Consensus Conference

(2010) M. Piram et al.   ANNALS OF THE RHEUMATIC DISEASES

Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France

(2010) L. Cuisset et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoinflammatory Diseases: Clinical and Genetic Advances

(2010) S. Farasat et al.   ARCHIVES OF DERMATOLOGY

Risk factors for severe Muckle-Wells syndrome

(2010) Jasmin B. Kümmerle-Deschner et al.   ARTHRITIS AND RHEUMATISM

The NLRP3 inflammasome, a target for therapy in diverse disease states

(2010) Graham P. Cook et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Canakinumab: a human anti-IL-1β monoclonal antibody for the treatment of cryopyrin-associated periodic syndromes

(2010) Leigh D Church et al.   Expert Review of Clinical Immunology

Translational research network and patient registry for auto-inflammatory diseases

(2010) E. Lainka et al.   RHEUMATOLOGY

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Long-term efficacy of the interleukin-1 receptor antagonist anakinra in ten patients with neonatal-onset multisystem inflammatory disease/chronic infantile neurologic, cutaneous, articular syndrome

(2009) Bénédicte Neven et al.   ARTHRITIS AND RHEUMATISM

In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes

(2009) Helen J. Lachmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome

(2009) Helen J. Lachmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and safety of rilonacept (interleukin-1 trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies

(2008) Hal M. Hoffman et al.   ARTHRITIS AND RHEUMATISM

The spectrum of monogenic autoinflammatory syndromes: Understanding disease mechanisms and use of targeted therapies

(2008) Rachel L. Glaser et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Familial cold auto-inflammatory syndrome (FCAS): characterization of symptomatology and impact on patients' lives

(2008) Beate Stych et al.   CURRENT MEDICAL RESEARCH AND OPINION

NLR, the nucleotide-binding domain leucine-rich repeat containing gene family

(2008) Zhengmao Ye et al.   CURRENT OPINION IN IMMUNOLOGY

The infevers autoinflammatory mutation online registry: update with new genes and functions

(2008) Florian Milhavet et al.   HUMAN MUTATION

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

(2008) Rieke Alten et al.   ARTHRITIS RESEARCH & THERAPY