Cinnamic Acid Derivatives and Their Biological Efficacy

Naturally occurring cinnamic acid derivatives prevent amyloid transformation of alpha-synuclein

(2020) Maria Medvedeva et al.   BIOCHIMIE

Design, synthesis, anti-TMV activity, and preliminary mechanism of cinnamic acid derivatives containing dithioacetal moiety

(2020) Yanju Wang et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Alpha-Synuclein Amyloid Aggregation Is Inhibited by Sulfated Aromatic Polymers and Pyridinium Polycation

(2020) Pavel Semenyuk et al.   Polymers

Tributyltin(IV) ferulate, a novel synthetic ferulic acid derivative, induces autophagic cell death in colon cancer cells: From chemical synthesis to biochemical effects

(2020) Claudia Pellerito et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Acaricidal activity and enzyme inhibitory activity of active compounds of essential oils against Psoroptes cuniculi

(2019) Xiao-Fei Shang et al.   VETERINARY PARASITOLOGY

Design, synthesis and biological evaluation of (E)-5-styryl-1,2,4-oxadiazoles as anti-tubercular agents

(2019) Abhay Atmaram Upare et al.   BIOORGANIC CHEMISTRY

β-Carboline and N-hydroxycinnamamide hybrids as anticancer agents for drug-resistant hepatocellular carcinoma

(2019) Yong Ling et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, mitochondrial localization of fluorescent derivatives of cinnamamide as anticancer agents

(2019) Kun Yang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of the novel oleanolic acid-cinnamic acid ester derivatives and glycyrrhetinic acid-cinnamic acid ester derivatives with cytotoxic properties

(2019) Rui Wang et al.   BIOORGANIC CHEMISTRY

Research progress in the biological activities of 3,4,5-trimethoxycinnamic acid (TMCA) derivatives

(2019) Zefeng Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents

(2019) Jingyu Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Phenolic acids, cinnamic acid, and ergosterol as cosmeceutical ingredients: Stabilization by microencapsulation to ensure sustained bioactivity

(2019) Oludemi Taofiq et al.   MICROCHEMICAL JOURNAL

Brazilian propolis extract reduces intestinal barrier defects and inflammation in a colitic mouse model

(2019) Yuki Shimizu et al.   NUTRITION RESEARCH

Evaluation of cinnamic acid and six analogues against eggs and larvae of Haemonchus contortus

(2019) Gabriela Mancilla-Montelongo et al.   VETERINARY PARASITOLOGY

In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis

(2019) Jordi Pijuan et al.   Frontiers in Cell and Developmental Biology

Anti-cancer effects of cinnamon: Insights into its apoptosis effects

(2019) Sahand Sadeghi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vitro methods to determine the antioxidant activity of caffeic acid

(2019) Caroline Magnani Spagnol et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships

(2019) Daniela Ribeiro et al.   BIOORGANIC CHEMISTRY

Design, synthesis and evaluation of novel ferulic acid derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease

(2019) Jin-Shuai Lan et al.   BIOORGANIC CHEMISTRY

Cinnamamide: An insight into the pharmacological advances and structure–activity relationships

(2019) Nikhil Gaikwad et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Insights into biological properties of less explored bark of industrially important Acacia catechu Willd

(2019) Rakesh Kumar et al.   INDUSTRIAL CROPS AND PRODUCTS

Cinnamic acid rescues behavioral deficits in a mouse model of traumatic brain injury by targeting miR-455-3p/HDAC2

(2019) Shewei Guo et al.   LIFE SCIENCES

Models for Understanding Resistance to Chemotherapy in Liver Cancer

(2019) Jose J. G. Marin et al.   Cancers

Hydroxyl substituted benzoic acid/cinnamic acid derivatives: Tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies

(2019) Yasir Nazir et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Harmicines − harmine and cinnamic acid hybrids as novel antiplasmodial hits

(2019) Ivana Perković et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of cinnamic acid derivatives and leishmanicidal activity against Leishmania braziliensis

(2019) Michelle Peixoto Rodrigues et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

6-Cinnamoyl-4-arylaminothienopyrimidines as highly potent cytotoxic agents: Design, synthesis and structure-activity relationship studies

(2019) Mahsa Toolabi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of coumarin derivatives as α-glucosidase inhibitors

(2019) Xue-Tao Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New cinnamic acid-pregenolone hybrids as potential antiproliferative agents: Design, synthesis and biological evaluation

(2019) Yong-Xi Ge et al.   STEROIDS

Effects of hydroxycinnamic acids on the reduction of furan and α-dicarbonyl compounds

(2019) Sang Mi Lee et al.   FOOD CHEMISTRY

Autophagy inhibition enhances anticancer efficacy of artepillin C, a cinnamic acid derivative in Brazilian green propolis

(2018) Satoshi Endo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chlorogenic acid (CGA): A pharmacological review and call for further research

(2018) Muhammad Naveed et al.   BIOMEDICINE & PHARMACOTHERAPY

Bioactivity and structure–activity relationship of cinnamic acid derivatives and its heteroaromatic ring analogues as potential high-efficient acaricides against Psoroptes cuniculi

(2018) Dong-Dong Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Theoretical study of the thermodynamics of the mechanisms underlying antiradical activity of cinnamic acid derivatives

(2018) Ana Amić et al.   FOOD CHEMISTRY

Evaluation of cinnamaldehyde and cinnamic acid derivatives in microbial growth control

(2018) J.F. Malheiro et al.   INTERNATIONAL BIODETERIORATION & BIODEGRADATION

Caffeic acid phenethyl ester down-regulates claudin-2 expression at the transcriptional and post-translational levels and enhances chemosensitivity to doxorubicin in lung adenocarcinoma A549 cells

(2018) Hiroyuki Sonoki et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Photoelectron spectra and biological activity of cinnamic acid derivatives revisited

(2018) Igor Novak et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Cinnamic acid derivatives in cosmetics - current use and future prospects

(2018) Agnieszka Gunia-Krzyżak et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Catalysis and inhibition of tyrosinase in the presence of cinnamic acid and some of its derivatives

(2018) Antonio Garcia-Jimenez et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antimicrobial Activity of Trans -Cinnamic Acid and Commonly Used Antibiotics Against Important Fish Pathogens and Non-Pathogenic Isolates

(2018) Sevdan Yilmaz et al.   JOURNAL OF APPLIED MICROBIOLOGY

Evaluation of the photosensitizing properties of zinc and indium tetra cinnamic acid phthalocyanines linked to magnetic nanoparticles on human breast adenocarcinoma cells

(2018) Gauta Gold Matlou et al.   JOURNAL OF LUMINESCENCE

Synthesis and antimetastatic activity evaluation of cinnamic acid derivatives containing 1,2,3-triazolic portions

(2018) Graziela Domingues de Almeida Lima et al.   TOXICOLOGY IN VITRO

Novel cinnamic acid-tryptamine hybrids as potent butyrylcholinesterase inhibitors: Synthesis, biological evaluation, and docking study

(2018) Shahrzad Ghafary et al.   ARCHIV DER PHARMAZIE

Optimization of substituted cinnamic acyl sulfonamide derivatives as tubulin polymerization inhibitors with anticancer activity

(2018) Yin Luo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cinnamic acid activates PPARα to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model

(2018) Sujyoti Chandra et al.   NEUROBIOLOGY OF DISEASE

Resveratrol-based cinnamic ester hybrids: synthesis, characterization, and anti-inflammatory activity

(2017) Ban-Feng Ruan et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer’s disease

(2017) Jin-Shuai Lan et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis and bioevaluation of new tacrine-cinnamic acid hybrids as cholinesterase inhibitors against Alzheimer’s disease

(2017) Yao Chen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Graphene/dodecanol floating solidification microextraction for the preconcentration of trace levels of cinnamic acid derivatives in traditional Chinese medicines

(2017) Shuang Hu et al.   JOURNAL OF SEPARATION SCIENCE

A new benzofuran derivative glycoside and a new coumarin glycoside from roots of Heracleum dissectum Ledeb

(2017) Jie Mi et al.   MEDICINAL CHEMISTRY RESEARCH

A new cinnamic acid glycoside from roots of Heracleum dissectum

(2017) Zhi-Gang Wang et al.   NATURAL PRODUCT RESEARCH

A new cinnamic acid derivative from plant-derived endophytic fungus Pyronema sp.

(2017) Zhangshuang Deng et al.   NATURAL PRODUCT RESEARCH

Antidiabetic and antihyperlipidemic activity of p -coumaric acid in diabetic rats, role of pancreatic GLUT 2: In vivo approach

(2016) Venkatesan Amalan et al.   BIOMEDICINE & PHARMACOTHERAPY

Antioxidant properties comparative study of natural hydroxycinnamic acids and structurally modified derivatives: Computational insights

(2016) Gloria Mazzone et al.   Computational and Theoretical Chemistry

Hair Dyes Resorcinol and Lawsone Reduce Production of Melanin in Melanoma Cells by Tyrosinase Activity Inhibition and Decreasing Tyrosinase and Microphthalmia-Associated Transcription Factor (MITF) Expression

(2015) Shu-Mei Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cinnamic Acid and Cinnamaldehyde Ameliorate Cisplatin-Induced Splenotoxicity in Rats

(2015) Ola M. Abd El-Raouf et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Natural Cinnamic Acids, Synthetic Derivatives and Hybrids with Antimicrobial Activity

(2014) Juan Guzman   MOLECULES

Anticancer Activity of Indian Stingless Bee Propolis: AnIn VitroStudy

(2013) Milind K. Choudhari et al.   Evidence-based Complementary and Alternative Medicine

Antifungal activity of cinnamic acid derivatives involves inhibition of benzoate 4-hydroxylase (CYP53)

(2013) B. Korošec et al.   JOURNAL OF APPLIED MICROBIOLOGY

Assessment of the Anti-invasion Potential and Mechanism of Select Cinnamic Acid Derivatives on Human Lung Adenocarcinoma Cells

(2013) Chiung-Man Tsai et al.   MOLECULAR PHARMACEUTICS

Multifunctional nanocarriers and intracellular drug delivery

(2012) Rupa R. Sawant et al.   CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE

Isolation of a new bioactive cinnamic acid derivative from the whole plant of Violabetonicifolia

(2012) Naveed Muhammad et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

In vitroeffects of cinnamic acid derivatives on protein tyrosine phosphatase 1B

(2012) Sirichai Adisakwattana et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Cinnamic Acid Derivatives as Anticancer Agents-A Review

(2011) P. De et al.   CURRENT MEDICINAL CHEMISTRY

Hybrid Lipids as a Biological Surface-Active Component

(2009) R. Brewster et al.   BIOPHYSICAL JOURNAL

A series of cinnamic acid derivatives and their inhibitory activity on intestinal α-glucosidase

(2009) Sirichai Adisakwattana et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

M1994 Selective Up-Regulation of Claudin-1 and Claudin-2 in Colorectal Cancer

(2008) Tetsushi Kinugasa   GASTROENTEROLOGY

Photodegradation of Cinnamic Acid in Different Media

(2008) E. Ugazio et al.   JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY

CYP53A15 of Cochliobolus lunatus, a Target for Natural Antifungal Compounds†

(2008) Barbara Podobnik et al.   JOURNAL OF MEDICINAL CHEMISTRY