Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody

Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin-4 channelopathies: a decade later

(2015) Sean J. Pittock et al.   Annals of the New York Academy of Sciences

The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model

(2015) Christian Geis et al.   EXPERIMENTAL NEUROLOGY

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

(2015) Dean M. Wingerchuk et al.   NEUROLOGY

Specificity and sensitivity of aquaporin 4 antibody detection tests in patients with neuromyelitis optica: A meta-analysis

(2015) Rafael Ruiz-Gaviria et al.   Multiple Sclerosis and Related Disorders

Longitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59

(2014) Hua Zhang et al.   JOURNAL OF AUTOIMMUNITY

Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G

(2014) Nithi Asavapanumas et al.   Journal of Neuroinflammation

Neuromyelitis optica pathology in rats following intraperitoneal injection of NMO-IgG and intracerebral needle injury

(2014) Nithi Asavapanumas et al.   Acta Neuropathologica Communications

Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions

(2013) Claudia Wrzos et al.   ACTA NEUROPATHOLOGICA

Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

(2013) Tatsuro Misu et al.   ACTA NEUROPATHOLOGICA

Experimental Models of Neuromyelitis Optica

(2013) Monika Bradl et al.   BRAIN PATHOLOGY

Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4

(2013) Kaori Miyazaki et al.   JOURNAL OF NEUROIMMUNOLOGY

Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study

(2013) Sean J Pittock et al.   LANCET NEUROLOGY

Immunological function of aquaporin-4 in stab-wounded mouse brain in concert with a pro-inflammatory cytokine inducer, osteopontin

(2013) Hiroko Ikeshima-Kataoka et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats

(2013) Maja Kitic et al.   Acta Neuropathologica Communications

T cell-activation in neuromyelitis optica lesions plays a role in their formation

(2013) Maria Pohl et al.   Acta Neuropathologica Communications

Complement-dependent Cytotoxicity in Neuromyelitis Optica Requires Aquaporin-4 Protein Assembly in Orthogonal Arrays

(2012) Puay-Wah Phuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aquaporin 4 and neuromyelitis optica

(2012) Marios C Papadopoulos et al.   LANCET NEUROLOGY

Protective effect of an elastase inhibitor in a neuromyelitis optica-like disease driven by a peptide of myelin oligodendroglial glycoprotein

(2012) Katja Herges et al.   Multiple Sclerosis Journal

Review of animal models of neuromyelitis optica

(2012) Melina V. Jones et al.   Multiple Sclerosis and Related Disorders

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement

(2011) Samira Saadoun et al.   JOURNAL OF NEUROIMMUNOLOGY

Clinical features of neuromyelitis optica in a large Japanese cohort: comparison between phenotypes

(2011) A. Nagaishi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Intravenous Neuromyelitis Optica Autoantibody in Mice Targets Aquaporin-4 in Peripheral Organs and Area Postrema

(2011) Julien Ratelade et al.   PLoS One

Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica

(2011) Norio Chihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-aquaporin-4 antibody induces astrocytic cytotoxicity in the absence of CNS antigen-specific T cells

(2010) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6

(2010) Akiyuki Uzawa et al.   Multiple Sclerosis Journal

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Astrocytic damage is far more severe than demyelination in NMO: A clinical CSF biomarker study

(2010) R. Takano et al.   NEUROLOGY

Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

(2009) Monika Bradl et al.   ANNALS OF NEUROLOGY

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deletion of Astrocyte Connexins 43 and 30 Leads to a Dysmyelinating Phenotype and Hippocampal CA1 Vacuolation

(2009) S. E. Lutz et al.   JOURNAL OF NEUROSCIENCE

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Acute Disseminated Encephalomyelitis: Current Understanding and Controversies

(2008) Nathan Young et al.   SEMINARS IN NEUROLOGY

Water movements in the brain: role of aquaporins

(2007) Matthew J. Tait et al.   TRENDS IN NEUROSCIENCES