Machine Learning-Guided Prediction of Antigen-Reactive In Silico Clonotypes Based on Changes in Clonal Abundance through Bio-Panning

Phage Display: An Overview in Context to Drug Discovery

(2019) Selena Mimmi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Next-generation sequencing-guided identification and reconstruction of antibody CDR combinations from phage selection outputs

(2019) Kris Barreto et al.   NUCLEIC ACIDS RESEARCH

High-throughput retrieval of physical DNA for NGS-identifiable clones in phage display library

(2019) Jinsung Noh et al.   mAbs

Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor–Mutant Non–Small-Cell Lung Cancer

(2019) Gillianne G.Y. Lai et al.   JOURNAL OF CLINICAL ONCOLOGY

HER2 Directed Antibody-Drug-Conjugates beyond T-DM1 in Breast Cancer

(2019) Gabriel Rinnerthaler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours

(2019) Valentina Martin et al.   BRITISH JOURNAL OF CANCER

First-in-human phase I trial of anti-hepatocyte growth factor (HGF) antibody (YYB101) in refractory solid tumor patients: Integrative pathologic-genomic analysis and the final results.

(2019) Jeeyun Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Phage Display in the Quest for New Selective Recognition Elements for Biosensors

(2019) Riikka Peltomaa et al.   ACS Omega

HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers

(2019) Fatemeh Moosavi et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Lysosome Fission: Planning for an Exit

(2019) Golam T. Saffi et al.   TRENDS IN CELL BIOLOGY

Antibody Complementarity Determining Region Design Using High-Capacity Machine Learning

(2019) Ge Liu et al.   BIOINFORMATICS

Computational approaches to therapeutic antibody design: established methods and emerging trends

(2019) Richard A Norman et al.   BRIEFINGS IN BIOINFORMATICS

Engineering strategies to overcome the current roadblocks in CAR T cell therapy

(2019) Sarwish Rafiq et al.   Nature Reviews Clinical Oncology

A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer

(2018) Amita Patnaik et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

MET-oncogenic and JAK2-inactivating alterations are independent factors that affect regulation of PD-L1 expression in lung cancer

(2018) Maria Saigi et al.   CLINICAL CANCER RESEARCH

FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation

(2018) Jinju Park et al.   Cancer Research and Treatment

Next-Generation Sequencing of Antibody Display Repertoires

(2018) Romain Rouet et al.   Frontiers in Immunology

Past, Present, and Future of Rituximab—The World’s First Oncology Monoclonal Antibody Therapy

(2018) Timothy M. Pierpont et al.   Frontiers in Oncology

Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method

(2018) Kannan Sankar et al.   mAbs

Oxford nanopore sequencing enables rapid discovery of single-domain antibodies from phage display libraries

(2018) Michael J Lowden et al.   BIOTECHNIQUES

HGF/MET and the Immune System: Relevance for Cancer Immunotherapy

(2018) Federica Papaccio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antibodies to watch in 2019

(2018) Hélène Kaplon et al.   mAbs

Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

(2017) Nicole Glodde et al.   IMMUNITY

Integrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering

(2017) Cristina Parola et al.   IMMUNOLOGY

ranger: A Fast Implementation of Random Forests for High Dimensional Data in C++ and R

(2017) Marvin N. Wright et al.   Journal of Statistical Software

In-silico prediction of concentration-dependent viscosity curves for monoclonal antibody solutions

(2017) Dheeraj S. Tomar et al.   mAbs

Application of modified yeast surface display technologies for non-Antibody protein engineering

(2017) Meng Mei et al.   MICROBIOLOGICAL RESEARCH

Tumour heterogeneity and resistance to cancer therapies

(2017) Ibiayi Dagogo-Jack et al.   Nature Reviews Clinical Oncology

Next generation sequencing of all variable loops of synthetic single framework scFv—Application in anti-HDL antibody selections

(2016) Janita Lövgren et al.   New Biotechnology

N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

(2016) Sha Sha et al.   TRENDS IN BIOTECHNOLOGY

Onartuzumab in lung cancer: the fall of Icarus?

(2015) Christian Rolfo et al.   Expert Review of Anticancer Therapy

Isolation and characterization of antigen-specific alpaca (Lama pacos) VHH antibodies by biopanning followed by high-throughput sequencing

(2015) Nobuo Miyazaki et al.   JOURNAL OF BIOCHEMISTRY

Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets

(2015) Anastasios Spiliotopoulos et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Aggregation risk prediction for antibodies and its application to biotherapeutic development

(2015) Olga Obrezanova et al.   mAbs

VH-VL orientation prediction for antibody humanization candidate selection: A case study

(2015) Alexander Bujotzek et al.   mAbs

Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Synthesis and Sequencing Technologies

(2015) Dongmei Hu et al.   PLoS One

Building Predictive Models inRUsing thecaretPackage

(2015) Max Kuhn   Journal of Statistical Software

Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions

(2014) Jasmin F. Sydow et al.   PLoS One

From deep sequencing to actual clones

(2014) S. D'Angelo et al.   PROTEIN ENGINEERING DESIGN & SELECTION

PEAR: a fast and accurate Illumina Paired-End reAd mergeR

(2013) J. Zhang et al.   BIOINFORMATICS

Deep sequencing of phage display libraries to support antibody discovery

(2013) Ulla Ravn et al.   METHODS

The Structural Basis of Antibody-Antigen Recognition

(2013) Inbal Sela-Culang et al.   Frontiers in Immunology

Methods for diversity and overlap analysis in T-cell receptor populations

(2012) Grzegorz A. Rempala et al.   JOURNAL OF MATHEMATICAL BIOLOGY

A new anti-c-met antibody selected by a mechanism-based dual-screening method: Therapeutic potential in cancer

(2012) Young Mi Oh et al.   MOLECULES AND CELLS

By-passing in vitro screening—next generation sequencing technologies applied to antibody display and in silico candidate selection

(2010) U. Ravn et al.   NUCLEIC ACIDS RESEARCH