High-throughput retrieval of physical DNA for NGS-identifiable clones in phage display library

Barcoded sequencing workflow for high throughput digitization of hybridoma antibody variable domain sequences

(2018) Yongmei Chen et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

(2018) Lindsay B. Avery et al.   mAbs

Unbiased quantification of immunoglobulin diversity at the DNA level with VDJ-seq

(2018) Peter Chovanec et al.   Nature Protocols

Synthesis and Characterisation of Photocrosslinked poly(ethylene glycol) diacrylate Implants for Sustained Ocular Drug Delivery

(2018) Kathryn McAvoy et al.   PHARMACEUTICAL RESEARCH

Next-Generation Sequencing of Antibody Display Repertoires

(2018) Romain Rouet et al.   Frontiers in Immunology

Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput

(2017) Todd M Gierahn et al.   NATURE METHODS

Biophysical properties of the clinical-stage antibody landscape

(2017) Tushar Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid and accurate in silico solubility screening of a monoclonal antibody library

(2017) Pietro Sormanni et al.   Scientific Reports

Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies

(2016) Masataka Umitsu et al.   Scientific Reports

Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

(2015) Amita Datta-Mannan et al.   mAbs

Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics

(2015) Angela Schoch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capillarity Guided Patterning of Microliquids

(2015) Myeongwoo Kang et al.   Small

Antibody Phage Display: Technique and Applications

(2014) Christoph M. Hammers et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge

(2014) Bing Li et al.   mAbs

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

(2014) Brandon J DeKosky et al.   NATURE MEDICINE

Towards error-free profiling of immune repertoires

(2014) Mikhail Shugay et al.   NATURE METHODS

Origins of specificity and affinity in antibody–protein interactions

(2014) Hung-Pin Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PEAR: a fast and accurate Illumina Paired-End reAd mergeR

(2013) J. Zhang et al.   BIOINFORMATICS

Drugs derived from phage display

(2013) Andrew E Nixon et al.   mAbs

Deep sequencing of phage display libraries to support antibody discovery

(2013) Ulla Ravn et al.   METHODS

Wrestling with the repertoire: The promise and perils of next generation sequencing for antigen receptors

(2012) Paul D. Baum et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Diversity of Phage-Displayed Libraries of Peptides during Panning and Amplification

(2011) Ratmir Derda et al.   MOLECULES

Beyond natural antibodies: the power of in vitro display technologies

(2011) Andrew R M Bradbury et al.   NATURE BIOTECHNOLOGY

Counting absolute numbers of molecules using unique molecular identifiers

(2011) Teemu Kivioja et al.   NATURE METHODS

Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries

(2011) Daniel Aird et al.   GENOME BIOLOGY

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

(2010) Sai T Reddy et al.   NATURE BIOTECHNOLOGY

A new bioinformatics analysis tools framework at EMBL-EBI

(2010) M. Goujon et al.   NUCLEIC ACIDS RESEARCH

By-passing in vitro screening—next generation sequencing technologies applied to antibody display and in silico candidate selection

(2010) U. Ravn et al.   NUCLEIC ACIDS RESEARCH

Next-Generation Phage Display: Integrating and Comparing Available Molecular Tools to Enable Cost-Effective High-Throughput Analysis

(2009) Emmanuel Dias-Neto et al.   PLoS One

Production and Characterization of Monoclonal Antibody to Botulinum Neurotoxin Type B Light Chain by Phage Display

(2008) Myung-Shin Lee et al.   HYBRIDOMA