Integrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering
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Title
Integrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering
Authors
Keywords
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Journal
IMMUNOLOGY
Volume 153, Issue 1, Pages 31-41
Publisher
Wiley
Online
2017-09-13
DOI
10.1111/imm.12838
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Note: Only part of the references are listed.- Quantifiable predictive features define epitope-specific T cell receptor repertoires
- (2017) Pradyot Dash et al. NATURE
- Identifying specificity groups in the T cell receptor repertoire
- (2017) Jacob Glanville et al. NATURE
- Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies
- (2016) Bryan Briney et al. CELL
- Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice
- (2016) Gopal Sapparapu et al. NATURE
- Ultra-high-throughput sequencing of the immune receptor repertoire from millions of lymphocytes
- (2016) Jonathan R McDaniel et al. Nature Protocols
- Next-Generation Sequencing of a Single Domain Antibody Repertoire Reveals Quality of Phage Display Selected Candidates
- (2016) Kendrick B. Turner et al. PLoS One
- Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires
- (2016) Brandon J. DeKosky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunogenomic engineering of a plug-and-(dis)play hybridoma platform
- (2016) Mark Pogson et al. Nature Communications
- Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting
- (2016) T. A. Khan et al. Science Advances
- Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
- (2015) Allon M. Klein et al. CELL
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Deep sequencing in library selection projects: what insight does it bring?
- (2015) J Glanville et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Direct high-throughput amplification and sequencing of immunoglobulin genes from single human B cells
- (2015) Rajagopal Murugan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Isolation and characterization of antigen-specific alpaca (Lama pacos) VHH antibodies by biopanning followed by high-throughput sequencing
- (2015) Nobuo Miyazaki et al. JOURNAL OF BIOCHEMISTRY
- Reproducibility: Standardize antibodies used in research
- (2015) Andrew Bradbury et al. NATURE
- Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Synthesis and Sequencing Technologies
- (2015) Dongmei Hu et al. PLoS One
- High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum
- (2015) Anders Christiansen et al. Scientific Reports
- Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining
- (2015) Bo Wang et al. Scientific Reports
- High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination
- (2014) Yann-Chong Tan et al. CLINICAL IMMUNOLOGY
- The promise and challenge of high-throughput sequencing of the antibody repertoire
- (2014) George Georgiou et al. NATURE BIOTECHNOLOGY
- Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery
- (2014) E-Chiang Lee et al. NATURE BIOTECHNOLOGY
- Biopharmaceutical benchmarks 2014
- (2014) Gary Walsh NATURE BIOTECHNOLOGY
- Towards error-free profiling of immune repertoires
- (2014) Mikhail Shugay et al. NATURE METHODS
- A robust pipeline for rapid production of versatile nanobody repertoires
- (2014) Peter C Fridy et al. NATURE METHODS
- IMGT®, the international ImMunoGeneTics information system® 25 years on
- (2014) Marie-Paule Lefranc et al. NUCLEIC ACIDS RESEARCH
- Identification and characterization of the constituent human serum antibodies elicited by vaccination
- (2014) Jason J. Lavinder et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice
- (2014) A. J. Murphy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-resolution antibody dynamics of vaccine-induced immune responses
- (2014) Uri Laserson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- From deep sequencing to actual clones
- (2014) S. D'Angelo et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Barcode-Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis
- (2014) Yann-Chong Tan et al. Arthritis & Rheumatology
- Development of humanized rabbit monoclonal antibodies against vascular endothelial growth factor receptor 2 with potential antitumor effects
- (2013) Yanlan Yu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Single-cell based high-throughput sequencing of full-length immunoglobulin heavy and light chain genes
- (2013) Christian E. Busse et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Specific binder for Lightning-Link® biotinylated proteins from an antibody phage library
- (2013) Fortunato Ferrara et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Comprehensive Interrogation of a Minimalist Synthetic CDR-H3 Library and Its Ability to Generate Antibodies with Therapeutic Potential
- (2013) Ciara M. Mahon et al. JOURNAL OF MOLECULAR BIOLOGY
- Deep sequencing of phage display libraries to support antibody discovery
- (2013) Ulla Ravn et al. METHODS
- High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
- (2013) Brandon J DeKosky et al. NATURE BIOTECHNOLOGY
- Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response
- (2013) Y. Wine et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic measurement of memory B-cell recall using antibody repertoire sequencing
- (2013) C. Vollmers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains
- (2013) J. Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts
- (2013) J. Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lineage Structure of the Human Antibody Repertoire in Response to Influenza Vaccination
- (2013) N. Jiang et al. Science Translational Medicine
- Using synthetic templates to design an unbiased multiplex PCR assay
- (2013) Christopher S. Carlson et al. Nature Communications
- Wrestling with the repertoire: The promise and perils of next generation sequencing for antigen receptors
- (2012) Paul D. Baum et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- A proteomics approach for the identification and cloning of monoclonal antibodies from serum
- (2012) Wan Cheung Cheung et al. NATURE BIOTECHNOLOGY
- Transferring the Characteristics of Naturally Occurring and Biased Antibody Repertoires to Human Antibody Libraries by Trapping CDRH3 Sequences
- (2012) Sophie Venet et al. PLoS One
- Construction of a rationally designed antibody platform for sequencing-assisted selection
- (2012) H. B. Larman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining
- (2012) I. Saggy et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Phage display screening without repetitious selection rounds
- (2011) Peter A.C. ’t Hoen et al. ANALYTICAL BIOCHEMISTRY
- Synthetic Antibodies Designed on Natural Sequence Landscapes
- (2011) Wenwu Zhai et al. JOURNAL OF MOLECULAR BIOLOGY
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Beyond natural antibodies: the power of in vitro display technologies
- (2011) Andrew R M Bradbury et al. NATURE BIOTECHNOLOGY
- Phenotype-information-phenotype cycle for deconvolution of combinatorial antibody libraries selected against complex systems
- (2011) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells
- (2010) Sai T Reddy et al. NATURE BIOTECHNOLOGY
- By-passing in vitro screening—next generation sequencing technologies applied to antibody display and in silico candidate selection
- (2010) U. Ravn et al. NUCLEIC ACIDS RESEARCH
- Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire
- (2009) J. Glanville et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-Throughput Sequencing of the Zebrafish Antibody Repertoire
- (2009) J. A. Weinstein et al. SCIENCE
- Measurement and Clinical Monitoring of Human Lymphocyte Clonality by Massively Parallel V-D-J Pyrosequencing
- (2009) S. D. Boyd et al. Science Translational Medicine
- Submitting antibodies to binding arbitration
- (2008) Stephen W Michnick et al. Nature Chemical Biology
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