Human Multilineage 3D Spheroids as a Model of Liver Steatosis and Fibrosis
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Human Multilineage 3D Spheroids as a Model of Liver Steatosis and Fibrosis
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 7, Pages 1629
Publisher
MDPI AG
Online
2019-04-03
DOI
10.3390/ijms20071629
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice
- (2019) Daniel Lindén et al. Molecular Metabolism
- Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease
- (2018) Juan Pablo Arab et al. Annual Review of Pathology-Mechanisms of Disease
- The role of PNPLA3 in health and disease
- (2018) Piero Pingitore et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis
- (2018) Kirstine S Tølbøl et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Effects of free omega-3 carboxylic acids and fenofibrate on liver fat content in patients with hypertriglyceridemia and non-alcoholic fatty liver disease: A double-blind, randomized, placebo-controlled study
- (2018) Jan Oscarsson et al. Journal of Clinical Lipidology
- Human hepatic 3D spheroids as a model for steatosis and insulin resistance
- (2018) Mikael Kozyra et al. Scientific Reports
- Non-alcoholic fatty liver disease (NAFLD) models in drug discovery
- (2017) Banumathi K. Cole et al. Expert Opinion on Drug Discovery
- Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis
- (2017) Parambir S. Dulai et al. HEPATOLOGY
- Transforming growth factor beta-1 (TGF-β1) stimulates collagen synthesis in cultured rainbow trout cardiac fibroblasts
- (2017) Elizabeth F. Johnston et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver
- (2017) P. Dongiovanni et al. JOURNAL OF INTERNAL MEDICINE
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- GLP-1 Analogue, Exendin-4, Modulates MAPKs Activity but not the Heat Shock Response in Human HepG2 Cells
- (2017) Dhanya Madhu et al. Proteomics Clinical Applications
- Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening
- (2016) Vlad Ratziu et al. GASTROENTEROLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis
- (2016) Piero Pingitore et al. HUMAN MOLECULAR GENETICS
- Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
- (2016) Matthew James Armstrong et al. LANCET
- Hepatic adaptations to maintain metabolic homeostasis in response to fasting and refeeding in mice
- (2016) C. E. Geisler et al. Nutrition & Metabolism
- Activated hepatic stellate cells play pivotal roles in hepatocellular carcinoma cell chemoresistance and migration in multicellular tumor spheroids
- (2016) Yeonhwa Song et al. Scientific Reports
- The importance of the interaction between hepatocyte and hepatic stellate cells in fibrogenesis induced by fatty accumulation
- (2015) Pablo J. Giraudi et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- The Genetic Variant I148M inPNPLA3Is Associated With Increased Hepatic Retinyl-Palmitate Storage in Humans
- (2015) Marketa Kovarova et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis
- (2015) Peri Kocabayoglu et al. JOURNAL OF HEPATOLOGY
- Statin use and non-alcoholic steatohepatitis in at risk individuals
- (2015) Paola Dongiovanni et al. JOURNAL OF HEPATOLOGY
- Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial
- (2015) Eleonora Scorletti et al. JOURNAL OF HEPATOLOGY
- PNPLA3 I148M Variant Influences Circulating Retinol in Adults with Nonalcoholic Fatty Liver Disease or Obesity
- (2015) Alison Mondul et al. JOURNAL OF NUTRITION
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- The interplay between hepatic stellate cells and hepatocytes in an in vitro model of NASH
- (2015) Varenka J. Barbero-Becerra et al. TOXICOLOGY IN VITRO
- Nonalcoholic fatty liver disease
- (2015) Elizabeth M. Brunt et al. Nature Reviews Disease Primers
- PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
- (2014) Carlo Pirazzi et al. HUMAN MOLECULAR GENETICS
- Lipids in health and disease
- (2014) Joshua Finkelstein et al. NATURE
- Circulating Triacylglycerol Signatures in Nonalcoholic Fatty Liver Disease Associated With the I148M Variant in PNPLA3 and With Obesity
- (2013) J. Hyysalo et al. DIABETES
- Hepatic stellate cells in liver development, regeneration, and cancer
- (2013) Chunyue Yin et al. JOURNAL OF CLINICAL INVESTIGATION
- The burden of liver disease in Europe: A review of available epidemiological data
- (2013) Martin Blachier et al. JOURNAL OF HEPATOLOGY
- Transforming Growth Factor β1 Induces the Expression of Collagen Type I by DNA Methylation in Cardiac Fibroblasts
- (2013) Xiaodong Pan et al. PLoS One
- Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease
- (2012) Norberto C Chavez-Tapia et al. BMC GASTROENTEROLOGY
- Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase
- (2012) Manju Kumari et al. Cell Metabolism
- Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats
- (2012) Naoki Kumashiro et al. HEPATOLOGY
- Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro
- (2012) Carlo Pirazzi et al. JOURNAL OF HEPATOLOGY
- From 3D cell culture to organs-on-chips
- (2011) Dongeun Huh et al. TRENDS IN CELL BIOLOGY
- Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
- (2010) Nitika Arora Gupta et al. HEPATOLOGY
- Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?
- (2008) Giovanna Mazzoleni et al. Genes and Nutrition
- Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
- (2008) Scott L. Friedman PHYSIOLOGICAL REVIEWS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started