Myasthenia Gravis: From the Viewpoint of Pathogenicity Focusing on Acetylcholine Receptor Clustering, Trans-Synaptic Homeostasis and Synaptic Stability
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Title
Myasthenia Gravis: From the Viewpoint of Pathogenicity Focusing on Acetylcholine Receptor Clustering, Trans-Synaptic Homeostasis and Synaptic Stability
Authors
Keywords
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Journal
Frontiers in Molecular Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-05-29
DOI
10.3389/fnmol.2020.00086
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Note: Only part of the references are listed.- Severe neurological toxicity of immune checkpoint inhibitors: growing spectrum
- (2020) Divyanshu Dubey et al. ANNALS OF NEUROLOGY
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- (2020) Zora Chui-Kuen Chan et al. NEUROSCIENCE LETTERS
- The role of the dystrophin glycoprotein complex on the neuromuscular system
- (2020) Dina C Belhasan et al. NEUROSCIENCE LETTERS
- Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis
- (2020) James F. Howard et al. JAMA Neurology
- Antagonism of the Neonatal Fc Receptor as an Emerging Treatment for Myasthenia Gravis
- (2020) Karissa L. Gable et al. Frontiers in Immunology
- Autoantibody Specificities in Myasthenia Gravis; Implications for Improved Diagnostics and Therapeutics
- (2020) Konstantinos Lazaridis et al. Frontiers in Immunology
- New Approaches to Targeting B Cells for Myasthenia Gravis Therapy
- (2020) Ruksana Huda Frontiers in Immunology
- Anti-LRP4 Antibody-associated Myasthenia Gravis with a Rare Complication of Thymoma Successfully Treated by Thymectomy
- (2020) Sho Aoki et al. INTERNAL MEDICINE
- Myasthenia gravis AChR antibodies inhibit function of rapsyn-clustered AChRs
- (2020) Hakan Cetin et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Differential response to rituximab in anti-AChR and anti-MuSK positive myasthenia gravis patients: a single-center retrospective study
- (2020) Tess Litchman et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Rapsyn as a signaling and scaffolding molecule in neuromuscular junction formation and maintenance
- (2020) Guanglin Xing et al. NEUROSCIENCE LETTERS
- Cancer immunotherapy with check point inhibitor can cause autoimmune adverse events due to loss of Treg homeostasis
- (2019) Prabhakaran Kumar et al. SEMINARS IN CANCER BIOLOGY
- Neuromuscular adverse events associated with anti-PD-1 monoclonal antibodies
- (2019) Annette Johansen et al. NEUROLOGY
- Long‐term safety and efficacy of eculizumab in generalized myasthenia gravis
- (2019) Srikanth Muppidi et al. MUSCLE & NERVE
- Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial
- (2019) Gil I Wolfe et al. LANCET NEUROLOGY
- Congenital myasthenic syndrome caused by novel COL13A1 mutations
- (2019) Marina Dusl et al. JOURNAL OF NEUROLOGY
- Correct expression and localization of collagen XIII are crucial for the normal formation and function of the neuromuscular system
- (2019) Heli Härönen et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Therapies Directed Against B-Cells and Downstream Effectors in Generalized Autoimmune Myasthenia Gravis: Current Status
- (2019) Grayson Beecher et al. DRUGS
- Collagen XIII and Other ECM Components in the Assembly and Disease of the Neuromuscular Junction
- (2019) Anne Heikkinen et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- The clinical spectrum of the congenital myasthenic syndrome resulting from COL13A1 mutations
- (2019) Pedro M. Rodríguez Cruz et al. BRAIN
- Salbutamol modifies the neuromuscular junction in a mouse model of ColQ myasthenic syndrome
- (2019) Grace M McMacken et al. HUMAN MOLECULAR GENETICS
- Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis
- (2019) James F. Howard et al. NEUROLOGY
- Myasthenia gravis
- (2019) Nils Erik Gilhus et al. Nature Reviews Disease Primers
- The congenital myasthenic syndromes
- (2019) An E. Vanhaesebrouck et al. CURRENT OPINION IN NEUROLOGY
- Efgartigimod improves muscle weakness in a mouse model for muscle-specific kinase myasthenia gravis
- (2019) Maartje G. Huijbers et al. EXPERIMENTAL NEUROLOGY
- Myasthenia Gravis Induced by Immune Checkpoint Inhibitors
- (2019) Ondine Becquart et al. JOURNAL OF IMMUNOTHERAPY
- Investigational RNAi Therapeutic Targeting C5 Is Efficacious in Pre-clinical Models of Myasthenia Gravis
- (2019) Linda L. Kusner et al. Molecular Therapy-Methods & Clinical Development
- Myasthenia Gravis: Pathogenic Effects of Autoantibodies on Neuromuscular Architecture
- (2019) Koneczny et al. Cells
- Next-generation Fc receptor–targeting biologics for autoimmune diseases
- (2019) Adrian W. Zuercher et al. AUTOIMMUNITY REVIEWS
- β2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure
- (2019) An E Vanhaesebrouck et al. BRAIN
- Congenital myasthenic syndrome due to mutations in MUSK suggests that the level of MuSK phosphorylation is crucial for governing synaptic structure
- (2019) Pedro M. Rodríguez Cruz et al. HUMAN MUTATION
- Neurological and related adverse events in immune checkpoint inhibitors: a pharmacovigilance study from the Japanese Adverse Drug Event Report database
- (2019) Kenichiro Sato et al. JOURNAL OF NEURO-ONCOLOGY
- Neurological Immune Related Adverse Events Associated with Nivolumab, Ipilimumab, and Pembrolizumab Therapy—Review of the Literature and Future Outlook
- (2019) Nora Möhn et al. Journal of Clinical Medicine
- Clinicopathologic Significance and Immunogenomic Analysis of Programmed Death-Ligand 1 (PD-L1) and Programmed Death 1 (PD-1) Expression in Thymic Epithelial Tumors
- (2019) Joon Seon Song et al. Frontiers in Oncology
- Overexpression of Dok-7 in skeletal muscle enhances neuromuscular transmission with structural alterations of neuromuscular junctions: Implications in robustness of neuromuscular transmission
- (2019) Takahiro Eguchi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Antigen-specific immunoadsorption of MuSK autoantibodies as a treatment of MuSK-induced experimental autoimmune myasthenia gravis
- (2019) Konstantinos Lazaridis et al. JOURNAL OF NEUROIMMUNOLOGY
- Maintenance immunosuppression in myasthenia gravis, an update
- (2019) John Morren et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- MuSK function during health and disease
- (2019) Ruth Herbst NEUROSCIENCE LETTERS
- SHP2 inhibitor protects AChRs from effects of myasthenia gravis MuSK antibody
- (2019) Saif Huda et al. Neurology-Neuroimmunology & Neuroinflammation
- Myasthenic syndromes due to defects in COL13A1 and in the N-linked glycosylation pathway
- (2018) David Beeson et al. Annals of the New York Academy of Sciences
- An imbalance between regulatory T cells and T helper 17 cells in acetylcholine receptor-positive myasthenia gravis patients
- (2018) Jose Adolfo Villegas et al. Annals of the New York Academy of Sciences
- Serological and experimental studies in different forms of myasthenia gravis
- (2018) Angela Vincent et al. Annals of the New York Academy of Sciences
- Agrin and LRP4 antibodies as new biomarkers of myasthenia gravis
- (2018) Min Yan et al. Annals of the New York Academy of Sciences
- Pathophysiological mechanisms of autoimmunity
- (2018) Muriel Sudres et al. Annals of the New York Academy of Sciences
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- (2018) Lei Li et al. Annual Review of Physiology
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- (2018) Pedro Rodríguez Cruz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Zhiguo Li et al. MUSCLE & NERVE
- Myasthenia gravis with muscle-specific tyrosine kinase antibodies: A narrative review
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- (2018) Min Yan et al. NEUROSCIENCE
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- (2018) Hakan Cetin et al. SEMINARS IN NEUROLOGY
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- (2018) Anna Simó et al. Frontiers in Molecular Neuroscience
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- (2018) Josep Tomàs et al. Frontiers in Pharmacology
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- (2018) Prabhakaran Kumar et al. JOURNAL OF AUTOIMMUNITY
- Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans
- (2018) Peter Ulrichts et al. JOURNAL OF CLINICAL INVESTIGATION
- Programmed cell death ligand 1 expression is upregulated in the skeletal muscle of patients with myasthenia gravis
- (2018) Kazuo Iwasa et al. JOURNAL OF NEUROIMMUNOLOGY
- Motoneuron Wnts regulate neuromuscular junction development
- (2018) Chengyong Shen et al. eLife
- Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis
- (2018) Katherine M. Clifford et al. MUSCLE & NERVE
- Immunotherapy in myasthenia gravis in the era of biologics
- (2018) Marinos C. Dalakas Nature Reviews Neurology
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- (2018) Yingkai Li et al. EXPERIMENTAL NEUROLOGY
- Immunization of mice with LRP4 induces myasthenia similar to MuSK-associated myasthenia gravis
- (2017) Shuuichi Mori et al. EXPERIMENTAL NEUROLOGY
- Trans-synaptic homeostasis at the myasthenic neuromuscular junction
- (2017) Jaap J Plomp Frontiers in Bioscience-Landmark
- Collagen XIII secures pre- and postsynaptic integrity of the neuromuscular synapse
- (2017) Heli Härönen et al. HUMAN MOLECULAR GENETICS
- Immunization with Recombinantly Expressed LRP4 Induces Experimental Autoimmune Myasthenia Gravis in C57BL/6 Mice
- (2017) Canan Ulusoy et al. IMMUNOLOGICAL INVESTIGATIONS
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- (2017) Masaharu Takamori INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2017) Claire Legay et al. JOURNAL OF NEUROCHEMISTRY
- Regulatory T cells in multiple sclerosis and myasthenia gravis
- (2017) K. M. Danikowski et al. Journal of Neuroinflammation
- Screening for lipoprotein receptor-related protein 4-, agrin-, and titin-antibodies and exploring the autoimmune spectrum in myasthenia gravis
- (2017) Isabell Cordts et al. JOURNAL OF NEUROLOGY
- Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless
- (2017) Daniel Alicea et al. JOURNAL OF NEUROSCIENCE
- The role of laminins in the organization and function of neuromuscular junctions
- (2017) Robert S. Rogers et al. MATRIX BIOLOGY
- Autoimmune antibodies to collagen XIII in myasthenia gravis patients
- (2017) Hongmin Tu et al. MUSCLE & NERVE
- Rituximab treatment of myasthenia gravis: A systematic review
- (2017) Rup Tandan et al. MUSCLE & NERVE
- B cells in the pathophysiology of myasthenia gravis
- (2017) John S. Yi et al. MUSCLE & NERVE
- Anti-LRP4 autoantibodies in Chinese patients with myasthenia gravis
- (2017) Yuan Li et al. MUSCLE & NERVE
- Ephedrine treatment for autoimmune myasthenia gravis
- (2017) Alexander F. Lipka et al. NEUROMUSCULAR DISORDERS
- Profile of upregulated inflammatory proteins in sera of Myasthenia Gravis patients
- (2017) Carl Johan Molin et al. Scientific Reports
- Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI
- (2017) Erica Hurtado et al. Frontiers in Molecular Neuroscience
- Silencing of Dok-7 in Adult Rat Muscle Increases Susceptibility to Passive Transfer Myasthenia Gravis
- (2016) Alejandro M. Gomez et al. AMERICAN JOURNAL OF PATHOLOGY
- Congenital myasthenic syndromes
- (2016) David Beeson CURRENT OPINION IN NEUROLOGY
- APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation
- (2016) Serena Stanga et al. FASEB JOURNAL
- Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution
- (2016) Leonor Remédio et al. GENES & DEVELOPMENT
- Caveolin-3 is aberrantly expressed in skeletal muscle cells in myasthenia gravis
- (2016) Kazuo Iwasa et al. JOURNAL OF NEUROIMMUNOLOGY
- Titin antibodies in “seronegative” myasthenia gravis — A new role for an old antigen
- (2016) C. Stergiou et al. JOURNAL OF NEUROIMMUNOLOGY
- Longitudinal epitope mapping in MuSK myasthenia gravis: implications for disease severity
- (2016) Maartje G. Huijbers et al. JOURNAL OF NEUROIMMUNOLOGY
- Reversible Recruitment of a Homeostatic Reserve Pool of Synaptic Vesicles Underlies Rapid Homeostatic Plasticity of Quantal Content
- (2016) X. Wang et al. JOURNAL OF NEUROSCIENCE
- β 2 -Adrenoceptor agonists as novel, safe and potentially effective therapies for Amyotrophic lateral sclerosis (ALS)
- (2016) Raymond T. Bartus et al. NEUROBIOLOGY OF DISEASE
- Enzymatic Activity of the Scaffold Protein Rapsyn for Synapse Formation
- (2016) Lei Li et al. NEURON
- Genetic Background Limits Generalizability of Genotype-Phenotype Relationships
- (2016) Laura J. Sittig et al. NEURON
- Imbalance of circulating CD4 + CXCR5 + FOXP3 + Tfr-like cells and CD4 + CXCR5 + FOXP3 − Tfh-like cells in myasthenia gravis
- (2016) Yanbin Wen et al. NEUROSCIENCE LETTERS
- MuSK is a BMP co-receptor that shapes BMP responses and calcium signaling in muscle cells
- (2016) Atilgan Yilmaz et al. Science Signaling
- Presynaptic muscarinic acetylcholine autoreceptors (M1, M2 and M4 subtypes), adenosine receptors (A1 and A2A) and tropomyosin-related kinase B receptor (TrkB) modulate the developmental synapse elimination process at the neuromuscular junction
- (2016) Laura Nadal et al. Molecular Brain
- Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin
- (2016) Elena Cortés-Vicente et al. JAMA Neurology
- MuSK is a BMP co-receptor that shapes BMP responses and calcium signaling in muscle cells
- (2016) Atilgan Yilmaz et al. Science Signaling
- R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5
- (2016) Hiroaki Nakashima et al. Scientific Reports
- Congenital Myasthenic Syndrome Type 19 Is Caused by Mutations in COL13A1, Encoding the Atypical Non-fibrillar Collagen Type XIII α1 Chain
- (2015) Clare V. Logan et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Myasthenia gravis and related disorders: Pathology and molecular pathogenesis
- (2015) James C. Ha et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Combination of agrin and laminin increase acetylcholine receptor clustering and enhance functional neuromuscular junction formationIn vitro
- (2015) Bill G.X. Zhang et al. Developmental Neurobiology
- Adenosine receptors and muscarinic receptors cooperate in acetylcholine release modulation in the neuromuscular synapse
- (2015) M. M. Santafe et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Electrophysiological analysis of neuromuscular synaptic function in myasthenia gravis patients and animal models
- (2015) Jaap J. Plomp et al. EXPERIMENTAL NEUROLOGY
- Transmission, Development, and Plasticity of Synapses
- (2015) Kathryn P. Harris et al. GENETICS
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- (2015) Jun Ma et al. JOURNAL OF NEUROPHYSIOLOGY
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- (2015) J. Messeant et al. JOURNAL OF NEUROSCIENCE
- Collagen Q – A potential target for autoantibodies in myasthenia gravis
- (2015) Marta Zoltowska Katarzyna et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Congenital myasthenic syndromes: pathogenesis, diagnosis, and treatment
- (2015) Andrew G Engel et al. LANCET NEUROLOGY
- Sorbs1 and 2 interact with Crk-L and are required for Acetylcholine receptor cluster formation
- (2015) Peter T. Hallock et al. MOLECULAR AND CELLULAR BIOLOGY
- Salbutamol and ephedrine in the treatment of severe AChR deficiency syndromes
- (2015) Pedro M. Rodríguez Cruz et al. NEUROLOGY
- A critical and previously unsuspected role for doublecortin at the neuromuscular junction in mouse and human
- (2015) F. Bourgeois et al. NEUROMUSCULAR DISORDERS
- Flow Cytofluorimetric Analysis of Anti-LRP4 (LDL Receptor-Related Protein 4) Autoantibodies in Italian Patients with Myasthenia Gravis
- (2015) Mariapaola Marino et al. PLoS One
- Bone morphogenetic protein signaling in vertebrate motor neurons and neuromuscular communication
- (2015) Nelson Osses et al. Frontiers in Cellular Neuroscience
- LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma
- (2015) Gabriella Cunha Vieira et al. Oncotarget
- Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation
- (2015) Haitao Wu et al. eLife
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- (2015) Kathryn P. Harris et al. GENETICS
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- (2015) Duygu Selcen et al. JAMA Neurology
- Clinical Features and Diagnostic Usefulness of Antibodies to Clustered Acetylcholine Receptors in the Diagnosis of Seronegative Myasthenia Gravis
- (2015) Pedro M. Rodríguez Cruz et al. JAMA Neurology
- Future perspectives in target-specific immunotherapies of myasthenia gravis
- (2015) Marinos C. Dalakas Therapeutic Advances in Neurological Disorders
- Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling
- (2015) Kenji Otsuka et al. Scientific Reports
- Cortactin autoantibodies in myasthenia gravis
- (2014) Eduard Gallardo et al. AUTOIMMUNITY REVIEWS
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- (2014) Sophie Nicole et al. BRAIN
- Crosstalk between Agrin and Wnt signaling pathways in development of vertebrate neuromuscular junction
- (2014) Arnab Barik et al. Developmental Neurobiology
- Myasthenia gravis: A comprehensive review of immune dysregulation and etiological mechanisms
- (2014) Sonia Berrih-Aknin et al. JOURNAL OF AUTOIMMUNITY
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- (2014) Ha Young Shin et al. Journal of Clinical Neurology
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- (2014) A. M. Gomez et al. JOURNAL OF IMMUNOLOGY
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- (2014) Lamprini Skriapa et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2014) A. Barik et al. JOURNAL OF NEUROSCIENCE
- Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton
- (2014) Y. Chen et al. JOURNAL OF NEUROSCIENCE
- Anti-agrin autoantibodies in myasthenia gravis
- (2014) C. Gasperi et al. NEUROLOGY
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- (2014) Bin Zhang et al. PLoS One
- Injection of a Soluble Fragment of Neural Agrin (NT-1654) Considerably Improves the Muscle Pathology Caused by the Disassembly of the Neuromuscular Junction
- (2014) Stefan Hettwer et al. PLoS One
- Effects of the ß2-Adrenoceptor Agonist, Albuterol, in a Mouse Model of Anti-MuSK Myasthenia Gravis
- (2014) Nazanin Ghazanfari et al. PLoS One
- The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses
- (2014) Tohru Tezuka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Degeneration of Neuromuscular Junction in Age and Dystrophy
- (2014) Rüdiger Rudolf et al. Frontiers in Aging Neuroscience
- The different roles of the thymus in the pathogenesis of the various myasthenia gravis subtypes
- (2013) Alexander Marx et al. AUTOIMMUNITY REVIEWS
- Complement associated pathogenic mechanisms in myasthenia gravis
- (2013) Erdem Tüzün et al. AUTOIMMUNITY REVIEWS
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- (2013) Amelia Evoli et al. AUTOIMMUNITY REVIEWS
- Pathophysiology of myasthenia gravis with antibodies to the acetylcholine receptor, muscle-specific kinase and low-density lipoprotein receptor-related protein 4
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- (2013) R. Nakata et al. EUROPEAN JOURNAL OF NEUROLOGY
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- (2013) Constanze Gallenmüller et al. NEUROMUSCULAR DISORDERS
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- (2013) Hui-Ju Chou et al. PLoS One
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- (2013) Inga Koneczny et al. PLoS One
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- (2013) M. G. Huijbers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) B. Zuber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Role of MuSK in Synapse Formation and Neuromuscular Disease
- (2013) S. J. Burden et al. Cold Spring Harbor Perspectives in Biology
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- (2013) Erhard Hohenester et al. Cell Adhesion & Migration
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- (2013) Hong Y Choi et al. eLife
- Neurexins
- (2013) Carsten Reissner et al. GENOME BIOLOGY
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- (2012) David P. Richman et al. Annals of the New York Academy of Sciences
- Synaptic basal lamina-associated congenital myasthenic syndromes
- (2012) Ricardo A. Maselli et al. Annals of the New York Academy of Sciences
- Structure of the neuromuscular junction: function and cooperative mechanisms in the synapse
- (2012) Masaharu Takamori Annals of the New York Academy of Sciences
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- (2012) Judith Cossins et al. Annals of the New York Academy of Sciences
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- (2012) Rinse Klooster et al. BRAIN
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- (2012) Yinong Zong et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2012) Jennifer Karmouch et al. CHEMICO-BIOLOGICAL INTERACTIONS
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- (2012) Muthusamy Thiruppathi et al. CLINICAL IMMUNOLOGY
- -Catenin gain of function in muscles impairs neuromuscular junction formation
- (2012) H. Wu et al. DEVELOPMENT
- Initiation of synapse formation by Wnt-induced MuSK endocytosis
- (2012) L. R. Gordon et al. DEVELOPMENT
- Serum Levels of Matrix Metalloproteinases: Implications in Clinical Neurology
- (2012) Fredrik Romi et al. EUROPEAN NEUROLOGY
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- (2012) Stuart Viegas et al. EXPERIMENTAL NEUROLOGY
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- (2012) Y. Zong et al. GENES & DEVELOPMENT
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- (2012) Kate Koles et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) S. T. Ngo et al. JOURNAL OF CELL SCIENCE
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- (2012) Madalina V. Nastase et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
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- (2012) Masaharu Takamori et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2012) A. R. Amenta et al. JOURNAL OF NEUROSCIENCE
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- (2012) John H. Caldwell et al. MECHANISMS OF DEVELOPMENT
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- (2012) Laure Strochlic et al. PLoS One
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- (2012) Trushar R. Patel et al. PLoS One
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- (2012) Melanie A. Samuel et al. PLoS One
- Molecular mechanisms underlying maturation and maintenance of the vertebrate neuromuscular junction
- (2012) Lei Shi et al. TRENDS IN NEUROSCIENCES
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- (2012) K. Koles et al. Cold Spring Harbor Perspectives in Biology
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- (2012) Bin Zhang et al. Molecular Brain
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- (2012) Michelle D. Amaral et al. NEURAL PLASTICITY
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- (2011) J. P. Henríquez et al. Acta Physiologica
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- (2011) Shuuichi Mori et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2011) John S. Tzartos ARCHIVES OF NEUROLOGY
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- (2011) Vivian Budnik et al. CURRENT OPINION IN NEUROBIOLOGY
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- (2011) Neha Singhal et al. Developmental Neurobiology
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- (2011) Geir Helgeland et al. EUROPEAN NEUROLOGY
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- (2011) Juan P. Henríquez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2011) Wei Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) P. Mohseni et al. JOURNAL OF NEUROSCIENCE
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- (2011) J. Chen et al. JOURNAL OF NEUROSCIENCE
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- (2011) Hiroshi Nishimune MOLECULAR NEUROBIOLOGY
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- (2011) Teerin Liewluck et al. MUSCLE & NERVE
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- (2010) Osamu Higuchi et al. ANNALS OF NEUROLOGY
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- (2010) Ruolan Liu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L
- (2010) P. T. Hallock et al. GENES & DEVELOPMENT
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- (2010) Ricardo A. Maselli et al. HUMAN MOLECULAR GENETICS
- Muscle Specific Kinase: Organiser of synaptic membrane domains
- (2010) Nazanin Ghazanfari et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Presynaptic calcium channels and α3-integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components
- (2010) Steven S. Carlson et al. JOURNAL OF NEUROCHEMISTRY
- Reduced thymic expression of ErbB receptors without auto-antibodies against synaptic ErbB in myasthenia gravis
- (2010) Kathleen Vrolix et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2010) L. Simeone et al. JOURNAL OF NEUROSCIENCE
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- (2010) A. Latvanlehto et al. JOURNAL OF NEUROSCIENCE
- The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization
- (2010) Elisa Bergamin et al. MOLECULAR CELL
- Pre- and postsynaptic neuromuscular junction abnormalities in musk myasthenia
- (2010) Erik H. Niks et al. MUSCLE & NERVE
- Ephedrine treatment in congenital myasthenic syndrome due to mutations in DOK7
- (2010) D. Lashley et al. NEUROLOGY
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- (2010) P. D. Yurchenco Cold Spring Harbor Perspectives in Biology
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- (2009) Andrea Babelova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Amy L. Stiegler et al. JOURNAL OF MOLECULAR BIOLOGY
- Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis
- (2009) Z. Wang et al. JOURNAL OF NEUROSCIENCE
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- (2009) Michael Hezel et al. MOLECULAR BIOLOGY OF THE CELL
- The Roles of the Dystrophin-Associated Glycoprotein Complex at the Synapse
- (2009) Gonneke S. K. Pilgram et al. MOLECULAR NEUROBIOLOGY
- Clinical findings in MuSK-antibody positive myasthenia gravis: A U.S. experience
- (2009) Mamatha Pasnoor et al. MUSCLE & NERVE
- Wnt Signals Organize Synaptic Prepattern and Axon Guidance through the Zebrafish unplugged/MuSK Receptor
- (2009) Lili Jing et al. NEURON
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- (2009) Y. Lee et al. NEUROSCIENCE
- The Function of Cortactin in the Clustering of Acetylcholine Receptors at the Vertebrate Neuromuscular Junction
- (2009) Raghavan Madhavan et al. PLoS One
- Dok-7 Activates the Muscle Receptor Kinase MuSK and Shapes Synapse Formation
- (2009) A. Inoue et al. Science Signaling
- Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction
- (2008) Rebecca N. Cole et al. ANNALS OF NEUROLOGY
- Response to Therapy in Myasthenia Gravis with Anti-MuSK Antibodies
- (2008) Amelia Evoli et al. Annals of the New York Academy of Sciences
- Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK
- (2008) Natalie Kim et al. CELL
- Wnt/β-Catenin Signaling Suppresses Rapsyn Expression and Inhibits Acetylcholine Receptor Clustering at the Neuromuscular Junction
- (2008) Jia Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
- (2008) Hiroshi Nishimune et al. JOURNAL OF CELL BIOLOGY
- Autoantibodies against TRPC3 and ryanodine receptor in myasthenia gravis
- (2008) Masaharu Takamori JOURNAL OF NEUROIMMUNOLOGY
- Lambert–Eaton myasthenic syndrome: Search for alternative autoimmune targets and possible compensatory mechanisms based on presynaptic calcium homeostasis
- (2008) Masaharu Takamori JOURNAL OF NEUROIMMUNOLOGY
- Retrograde regulation of motoneuron differentiation by muscle β-catenin
- (2008) Xiao-Ming Li et al. NATURE NEUROSCIENCE
- HSP90β Regulates Rapsyn Turnover and Subsequent AChR Cluster Formation and Maintenance
- (2008) Shiwen Luo et al. NEURON
- LRP4 Serves as a Coreceptor of Agrin
- (2008) Bin Zhang et al. NEURON
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- (2008) Jenny Linnoila et al. NEURON
- Wnt signaling promotes AChR aggregation at the neuromuscular synapse in collaboration with agrin
- (2008) J. P. Henriquez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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