Antibodies against low-density lipoprotein receptor–related protein 4 induce myasthenia gravis

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling

(2013) Y. Ahn et al.   DEVELOPMENT

The Role of MuSK in Synapse Formation and Neuromuscular Disease

(2013) S. J. Burden et al.   Cold Spring Harbor Perspectives in Biology

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

(2012) Rinse Klooster et al.   BRAIN

 -Catenin gain of function in muscles impairs neuromuscular junction formation

(2012) H. Wu et al.   DEVELOPMENT

Passive and active immunization models of MuSK-Ab positive myasthenia: Electrophysiological evidence for pre and postsynaptic defects

(2012) Stuart Viegas et al.   EXPERIMENTAL NEUROLOGY

Structural basis of agrin-LRP4-MuSK signaling

(2012) Y. Zong et al.   GENES & DEVELOPMENT

Distinct Roles of Muscle and Motoneuron LRP4 in Neuromuscular Junction Formation

(2012) Haitao Wu et al.   NEURON

Wnt proteins regulate acetylcholine receptor clustering in muscle cells

(2012) Bin Zhang et al.   Molecular Brain

Antibodies against Muscle-Specific Kinase Impair Both Presynaptic and Postsynaptic Functions in a Murine Model of Myasthenia Gravis

(2011) Shuuichi Mori et al.   AMERICAN JOURNAL OF PATHOLOGY

Acute Severe Animal Model of Anti–Muscle-Specific Kinase Myasthenia

(2011) Kayoko Nishi   ARCHIVES OF NEUROLOGY

Autoantibodies to Lipoprotein-Related Protein 4 in Patients With Double-Seronegative Myasthenia Gravis

(2011) John S. Tzartos   ARCHIVES OF NEUROLOGY

Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice

(2011) Anna Rostedt Punga et al.   EXPERIMENTAL NEUROLOGY

Agrin Binds to the N-terminal Region of Lrp4 Protein and Stimulates Association between Lrp4 and the First Immunoglobulin-like Domain in Muscle-specific Kinase (MuSK)

(2011) Wei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis

(2011) Alexandra Pevzner et al.   JOURNAL OF NEUROLOGY

Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis

(2010) Osamu Higuchi et al.   ANNALS OF NEUROLOGY

A systematic review of population based epidemiological studies in Myasthenia Gravis

(2010) Aisling S Carr et al.   BMC Neurology

To build a synapse: signaling pathways in neuromuscular junction assembly

(2010) H. Wu et al.   DEVELOPMENT

Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice

(2010) R. N. Cole et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lrp4 Regulates Initiation of Ureteric Budding and Is Crucial for Kidney Formation – A Mouse Model for Cenani-Lenz Syndrome

(2010) Courtney M. Karner et al.   PLoS One

The Effect of Plasma From Muscle-Specific Tyrosine Kinase Myasthenia Patients on Regenerating Endplates

(2009) W. Pascale ter Beek et al.   AMERICAN JOURNAL OF PATHOLOGY

Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction

(2008) Rebecca N. Cole et al.   ANNALS OF NEUROLOGY

Myasthenia Gravis Experimentally Induced with Muscle-specific Kinase

(2008) Kazuhiro Shigemoto et al.   Annals of the New York Academy of Sciences

Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK

(2008) Natalie Kim et al.   CELL

HSP90β Regulates Rapsyn Turnover and Subsequent AChR Cluster Formation and Maintenance

(2008) Shiwen Luo et al.   NEURON

LRP4 Serves as a Coreceptor of Agrin

(2008) Bin Zhang et al.   NEURON