Molecular Mechanism of Active Zone Organization at Vertebrate Neuromuscular Junctions

Maturation of active zone assembly byDrosophilaBruchpilot

(2016) Wernher Fouquet et al.   JOURNAL OF CELL BIOLOGY

RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction

(2011) Pascal S. Kaeser et al.   CELL

Transsynaptic channelosomes

(2011) Hiroshi Nishimune   Channels

Calcium Channels Link the Muscle-Derived Synapse Organizer Laminin  2 to Bassoon and CAST/Erc2 to Organize Presynaptic Active Zones

(2011) J. Chen et al.   JOURNAL OF NEUROSCIENCE

Single-Pixel Optical Fluctuation Analysis of Calcium Channel Function in Active Zones of Motor Nerve Terminals

(2011) F. Luo et al.   JOURNAL OF NEUROSCIENCE

Hts/Adducin Controls Synaptic Elaboration and Elimination

(2011) Jan Pielage et al.   NEURON

RIM Determines Ca2+ Channel Density and Vesicle Docking at the Presynaptic Active Zone

(2011) Yunyun Han et al.   NEURON

Neuropathology in Mice Expressing Mouse Alpha-Synuclein

(2011) Claus Rieker et al.   PLoS One

RIM proteins and their role in synapse function

(2010) Tobias Mittelstaedt et al.   BIOLOGICAL CHEMISTRY

A Drosophila model of GSS syndrome suggests defects in active zones are responsible for pathogenesis of GSS syndrome

(2010) Jin-Kyu Choi et al.   HUMAN MOLECULAR GENETICS

CAST and ELKS proteins: structural and functional determinants of the presynaptic active zone

(2010) Y. Hida et al.   JOURNAL OF BIOCHEMISTRY

Rab3-interacting Molecule γ Isoforms Lacking the Rab3-binding Domain Induce Long Lasting Currents but Block Neurotransmitter Vesicle Anchoring in Voltage-dependent P/Q-type Ca2+Channels

(2010) Yoshitsugu Uriu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Active Zone T-Bar—A Plasticity Module?

(2010) Carolin Wichmann et al.   JOURNAL OF NEUROGENETICS

Muscle-Derived Collagen XIII Regulates Maturation of the Skeletal Neuromuscular Junction

(2010) A. Latvanlehto et al.   JOURNAL OF NEUROSCIENCE

Onset Coding Is Degraded in Auditory Nerve Fibers from Mutant Mice Lacking Synaptic Ribbons

(2010) B. N. Buran et al.   JOURNAL OF NEUROSCIENCE

Impaired development of hippocampal mossy fibre synapses in mouse mutants for the presynaptic scaffold protein Bassoon

(2010) Frederic Lanore et al.   JOURNAL OF PHYSIOLOGY-LONDON

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Bassoon and the Synaptic Ribbon Organize Ca2+ Channels and Vesicles to Add Release Sites and Promote Refilling

(2010) Thomas Frank et al.   NEURON

Bassoon Speeds Vesicle Reloading at a Central Excitatory Synapse

(2010) Stefan Hallermann et al.   NEURON

Neuromuscular pathology in mice lacking alpha-synuclein

(2010) Anssi Pelkonen et al.   NEUROSCIENCE LETTERS

Targeted deletion of  III spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes

(2010) M. C. Stankewich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain

(2010) C. S. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis

(2010) K. Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembling the presynaptic active zone

(2009) David Owald et al.   CURRENT OPINION IN NEUROBIOLOGY

Macromolecular connections of active zone material to docked synaptic vesicles and presynaptic membrane at neuromuscular junctions of mouse

(2009) Sharuna Nagwaney et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Targeted three-dimensional immunohistochemistry reveals localization of presynaptic proteins Bassoon and Piccolo in the rat calyx of Held before and after the onset of hearing

(2009) Anna Dondzillo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Mutations in LAMB2 causing a severe form of synaptic congenital myasthenic syndrome

(2009) R A Maselli et al.   JOURNAL OF MEDICAL GENETICS

Unc-51 Controls Active Zone Density and Protein Composition by Downregulating ERK Signaling

(2009) Y. P. Wairkar et al.   JOURNAL OF NEUROSCIENCE

Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis

(2009) Z. Wang et al.   JOURNAL OF NEUROSCIENCE

A Protein Interaction Node at the Neurotransmitter Release Site: Domains of Aczonin/Piccolo, Bassoon, CAST, and Rim Converge on the N-Terminal Domain of Munc13-1

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Presynaptic α2δ-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions

(2009) Peri T Kurshan et al.   NATURE NEUROSCIENCE

Vision and visual cortical maps in mice with a photoreceptor synaptopathy: Reduced but robust visual capabilities in the absence of synaptic ribbons

(2009) Bianka Goetze et al.   NEUROIMAGE

Rab3 Dynamically Controls Protein Composition at Active Zones

(2009) Ethan R. Graf et al.   NEURON

ELKS2α/CAST Deletion Selectively Increases Neurotransmitter Release at Inhibitory Synapses

(2009) Pascal S. Kaeser et al.   NEURON

Molecular Mechanisms of Presynaptic Differentiation

(2008) Yishi Jin et al.   Annual Review of Cell and Developmental Biology

Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK

(2008) Natalie Kim et al.   CELL

Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction

(2008) Hiroshi Nishimune et al.   JOURNAL OF CELL BIOLOGY

straightjacketis required for the synaptic stabilization ofcacophony, a voltage-gated calcium channel α1subunit

(2008) Cindy V. Ly et al.   JOURNAL OF CELL BIOLOGY

Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: The involvement of precursor spheres

(2008) Hanna Regus-Leidig et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Heterogeneity in Synaptic Vesicle Release at Neuromuscular Synapses of Mice Expressing SynaptopHluorin

(2008) R. M. Wyatt et al.   JOURNAL OF NEUROSCIENCE

Mutations in a Drosophila  2  Voltage-Gated Calcium Channel Subunit Reveal a Crucial Synaptic Function

(2008) D. K. Dickman et al.   JOURNAL OF NEUROSCIENCE

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

(2008) P F Sullivan et al.   MOLECULAR PSYCHIATRY

New Dogs in the Dogma: Lrp4 and Tid1 in Neuromuscular Synapse Formation

(2008) Yuanquan Song et al.   NEURON

LRP4 Serves as a Coreceptor of Agrin

(2008) Bin Zhang et al.   NEURON