Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection
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Title
Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection
Authors
Keywords
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Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-05-08
DOI
10.1038/s41467-020-16143-6
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Note: Only part of the references are listed.- Retention of EsxA in the capsule-like layer of Mycobacterium tuberculosis is associated with cytotoxicity and is counteracted by lung surfactant
- (2019) Johanna Raffetseder et al. INFECTION AND IMMUNITY
- The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection
- (2019) Ana T. López-Jiménez et al. PLoS Pathogens
- Immunity to the Dual Threat of Silica Exposure and Mycobacterium tuberculosis
- (2019) Petr Konečný et al. Frontiers in Immunology
- Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia
- (2019) Ebba Abate et al. Scientific Reports
- Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition
- (2019) Jessica Gräb et al. Nature Communications
- A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis
- (2019) Eduardo P. Amaral et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Alternative splicing regulates stochastic NLRP3 activity
- (2019) Florian Hoss et al. Nature Communications
- Annexin A7 is required for ESCRT III-mediated plasma membrane repair
- (2019) Stine Lauritzen Sønder et al. Scientific Reports
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
- (2018) Charles L. Evavold et al. IMMUNITY
- Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
- (2018) Dave Boucher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Targeting the NLRP3 inflammasome in inflammatory diseases
- (2018) Matthew S. J. Mangan et al. NATURE REVIEWS DRUG DISCOVERY
- Orchestration of NLRP3 Inflammasome Activation by Ion Fluxes
- (2018) Tao Gong et al. TRENDS IN IMMUNOLOGY
- NAD + Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis
- (2018) David Pajuelo et al. Cell Reports
- Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages
- (2018) Eduardo P. Amaral et al. Frontiers in Immunology
- New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
- (2018) Zhenyu Zhong et al. NATURE
- Pyroptosis versus necroptosis: similarities, differences, and crosstalk
- (2018) Daniel Frank et al. CELL DEATH AND DIFFERENTIATION
- PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
- (2018) Jueqi Chen et al. NATURE
- Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
- (2018) Pontus Orning et al. SCIENCE
- ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
- (2018) Sebastian Rühl et al. SCIENCE
- Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response
- (2018) Ekansh Mittal et al. mBio
- Dynamics of in vivo ASC speck formation
- (2017) Paola Kuri et al. JOURNAL OF CELL BIOLOGY
- Mycobacterium tuberculosisreplicates within necrotic human macrophages
- (2017) Thomas R. Lerner et al. JOURNAL OF CELL BIOLOGY
- MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D
- (2017) Kimberley D. Gutierrez et al. JOURNAL OF IMMUNOLOGY
- Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages
- (2017) X Zhao et al. Mucosal Immunology
- Host-directed therapies for bacterial and viral infections
- (2017) Stefan H. E. Kaufmann et al. NATURE REVIEWS DRUG DISCOVERY
- Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions
- (2017) William H. Conrad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
- (2017) Stephanie A. Conos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
- (2017) Liliane Christ et al. TRENDS IN BIOCHEMICAL SCIENCES
- The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity
- (2017) Katharina S. Schneider et al. Cell Reports
- Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells
- (2017) Deeqa Mahamed et al. eLife
- Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan
- (2016) Andrea J. Wolf et al. CELL
- Inflammasome Complexes: Emerging Mechanisms and Effector Functions
- (2016) Vijay A.K. Rathinam et al. CELL
- Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses
- (2016) Katrin D Mayer-Barber et al. Cellular & Molecular Immunology
- Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access
- (2016) Roxane Simeone et al. CELLULAR MICROBIOLOGY
- K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
- (2016) Christina J. Groß et al. IMMUNITY
- Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis
- (2016) Thomas R. Lerner et al. JOURNAL OF CLINICAL INVESTIGATION
- Pore-forming activity and structural autoinhibition of the gasdermin family
- (2016) Jingjin Ding et al. NATURE
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
- (2015) Robert O. Watson et al. Cell Host & Microbe
- Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
- (2015) Ruth Wassermann et al. Cell Host & Microbe
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling
- (2015) Christina Antonopoulos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
- (2015) Gregory M. Orlowski et al. JOURNAL OF IMMUNOLOGY
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD
- (2015) Jim Sun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis
- (2015) Anca Dorhoi et al. Seminars in Immunopathology
- Mitochondria: diversity in the regulation of the NLRP3 inflammasome
- (2015) Prajwal Gurung et al. TRENDS IN MOLECULAR MEDICINE
- The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD
- (2015) Jim Sun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo
- (2015) Roxane Simeone et al. PLoS Pathogens
- Seeing a Mycobacterium-Infected Cell in Nanoscale 3D: Correlative Imaging by Light Microscopy and FIB/SEM Tomography
- (2015) Marianne Sandvold Beckwith et al. PLoS One
- Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation
- (2015) Prajwal Gurung et al. Scientific Reports
- Regulated necrosis: the expanding network of non-apoptotic cell death pathways
- (2014) Tom Vanden Berghe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Easy quantitative assessment of genome editing by sequence trace decomposition
- (2014) Eva K. Brinkman et al. NUCLEIC ACIDS RESEARCH
- An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity
- (2014) O. Danilchanka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ESCRT Machinery Is Required for Plasma Membrane Repair
- (2014) A. J. Jimenez et al. SCIENCE
- Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair
- (2014) Luana L. Scheffer et al. Nature Communications
- Single-Cell Imaging of Caspase-1 Dynamics Reveals an All-or-None Inflammasome Signaling Response
- (2014) Ting Liu et al. Cell Reports
- Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation
- (2013) Shankar S. Iyer et al. IMMUNITY
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Intracellular Bacillary Burden Reflects a Burst Size for Mycobacterium tuberculosis In Vivo
- (2013) Teresa Repasy et al. PLoS Pathogens
- Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
- (2012) Robert O. Watson et al. CELL
- ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
- (2012) Diane Houben et al. CELLULAR MICROBIOLOGY
- Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
- (2012) Kenichi Shimada et al. IMMUNITY
- Critical role of AIM2 in Mycobacterium tuberculosis infection
- (2012) H. Saiga et al. INTERNATIONAL IMMUNOLOGY
- Mycobacterium tuberculosisESAT-6 Exhibits a Unique Membrane-interacting Activity That Is Not Found in Its Ortholog from Non-pathogenicMycobacterium smegmatis
- (2012) Joaquin De Leon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death
- (2012) Roxane Simeone et al. PLoS Pathogens
- Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis
- (2011) Ka-Wing Wong et al. CELLULAR MICROBIOLOGY
- Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis
- (2011) Anca Dorhoi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mycobacterial Secretion Systems ESX-1 and ESX-5 Play Distinct Roles in Host Cell Death and Inflammasome Activation
- (2011) A. M. Abdallah et al. JOURNAL OF IMMUNOLOGY
- Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization
- (2011) Kristian Berg et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- Mycobacterium tuberculosis Induces an Atypical Cell Death Mode to Escape from Infected Macrophages
- (2011) Jinhee Lee et al. PLoS One
- Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1- and Cathepsin B-Independent Necrosis
- (2011) Amanda Welin et al. PLoS One
- Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
- (2010) Bibhuti B. Mishra et al. CELLULAR MICROBIOLOGY
- Imaging with total internal reflection fluorescence microscopy for the cell biologist
- (2010) A. L. Mattheyses et al. JOURNAL OF CELL SCIENCE
- Cutting Edge: Caspase-1 Independent IL-1 Production Is Critical for Host Resistance to Mycobacterium tuberculosis and Does Not Require TLR Signaling In Vivo
- (2010) K. D. Mayer-Barber et al. JOURNAL OF IMMUNOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins
- (2010) Musa Sani et al. PLoS Pathogens
- Galectin-3, a marker for vacuole lysis by invasive pathogens
- (2009) Irit Paz et al. CELLULAR MICROBIOLOGY
- The RD1 Locus in the Mycobacterium tuberculosis Genome Contributes to Activation of Caspase-1 via Induction of Potassium Ion Efflux in Infected Macrophages
- (2009) T. Kurenuma et al. INFECTION AND IMMUNITY
- Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β
- (2009) Miyako Okamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
- (2009) Tilmann Bürckstümmer et al. NATURE IMMUNOLOGY
- Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair
- (2009) Maziar Divangahi et al. NATURE IMMUNOLOGY
- Differential requirement for the activation of the inflammasome for processing and release of IL-1 in monocytes and macrophages
- (2008) M. G. Netea et al. BLOOD
- Evidence for Pore Formation in Host Cell Membranes by ESX-1-Secreted ESAT-6 and Its Role in Mycobacterium marinum Escape from the Vacuole
- (2008) J. Smith et al. INFECTION AND IMMUNITY
- Plasma membrane deformation by circular arrays of ESCRT-III protein filaments
- (2008) Phyllis I. Hanson et al. JOURNAL OF CELL BIOLOGY
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
- (2008) Veit Hornung et al. NATURE IMMUNOLOGY
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