The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells

(2018) Thomas R. Lerner et al.   BMC BIOLOGY

Galectins Control mTOR in Response to Endomembrane Damage

(2018) Jingyue Jia et al.   MOLECULAR CELL

Triggered recruitment of ESCRT machinery promotes endolysosomal repair

(2018) Michael L. Skowyra et al.   SCIENCE

ESCRT and autophagies: Endosomal functions and beyond

(2018) Christophe Lefebvre et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ESCRT-dependent cargo sorting at multivesicular endosomes

(2018) E.B. Frankel et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ESCRT-dependent control of membrane remodelling during cell division

(2018) Caroline Louise Stoten et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

When Dicty Met Myco, a (Not So) Romantic Story about One Amoeba and Its Intracellular Pathogen

(2018) Elena Cardenal-Muñoz et al.   Frontiers in Cellular and Infection Microbiology

Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses

(2018) Joe Dan Dunn et al.   Frontiers in Immunology

ESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival

(2018) Maja Radulovic et al.   EMBO JOURNAL

L-leucyl-L-leucine methyl ester does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes

(2017) Urska Repnik et al.   JOURNAL OF CELL SCIENCE

Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions

(2017) William H. Conrad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MitoNEET-dependent formation of intermitochondrial junctions

(2017) Alexandre Vernay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis

(2017) Jeff Quigley et al.   mBio

Mycobacterium marinum Degrades Both Triacylglycerols and Phospholipids from Its Dictyostelium Host to Synthesise Its Own Triacylglycerols and Generate Lipid Inclusions

(2017) Caroline Barisch et al.   PLoS Pathogens

Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner

(2017) Elena Cardenal-Muñoz et al.   PLoS Pathogens

TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis

(2016) Santosh Chauhan et al.   DEVELOPMENTAL CELL

Reverse-topology membrane scission by the ESCRT proteins

(2016) Johannes Schöneberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation

(2015) Nicolas Chiaruttini et al.   CELL

Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1

(2015) Saskia Kreibich et al.   Cell Host & Microbe

Lipid droplet dynamics at early stages ofMycobacterium marinuminfection inDictyostelium

(2015) Caroline Barisch et al.   CELLULAR MICROBIOLOGY

ESCRTs are everywhere

(2015) J. H. Hurley   EMBO JOURNAL

ESCRT Machinery Is Required for Plasma Membrane Repair

(2014) A. J. Jimenez et al.   SCIENCE

Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair

(2014) Luana L. Scheffer et al.   Nature Communications

Virus Budding and the ESCRT Pathway

(2013) Jörg Votteler et al.   Cell Host & Microbe

The role of ‘eat-me’ signals and autophagy cargo receptors in innate immunity

(2013) Keith B. Boyle et al.   CURRENT OPINION IN MICROBIOLOGY

Dictyostelium Lipid Droplets Host Novel Proteins

(2013) Xiaoli Du et al.   EUKARYOTIC CELL

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

(2013) Paolo S. Manzanillo et al.   NATURE

ALIX and the multivesicular endosome: ALIX in Wonderland

(2013) Christin Bissig et al.   TRENDS IN CELL BIOLOGY

Autophagy as an innate defense against mycobacteria

(2013) Eun-Kyeong Jo   Pathogens and Disease

The Tim3-Galectin 9 Pathway Induces Antibacterial Activity in Human Macrophages Infected with Mycobacterium tuberculosis

(2012) I. Sada-Ovalle et al.   JOURNAL OF IMMUNOLOGY

Prison Break: Pathogens' Strategies To Egress from Host Cells

(2012) Nikolas Friedrich et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Mycobacteria and the Intraphagosomal Environment: Take It With a Pinch of Salt(s)!

(2012) Thierry Soldati et al.   TRAFFIC

Mycobacterium marinum induces a marked LC3 recruitment to its containing phagosome that depends on a functional ESX-1 secretion system

(2011) María Cecilia Lerena et al.   CELLULAR MICROBIOLOGY

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

(2011) Laeticia Alibaud et al.   MOLECULAR MICROBIOLOGY

How Ubiquitin Functions with ESCRTs

(2011) S. Brookhart Shields et al.   TRAFFIC

Tim3 binding to galectin-9 stimulates antimicrobial immunity

(2010) Pushpa Jayaraman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sensitive Detection of Gene Expression in Mycobacteria under Replicating and Non-Replicating Conditions Using Optimized Far-Red Reporters

(2010) Paul Carroll et al.   PLoS One

Optimisation of Bioluminescent Reporters for Use with Mycobacteria

(2010) Nuria Andreu et al.   PLoS One

Functional Reconstitution of ESCRT-III Assembly and Disassembly

(2009) Suraj Saksena et al.   CELL

Galectin-3, a marker for vacuole lysis by invasive pathogens

(2009) Irit Paz et al.   CELLULAR MICROBIOLOGY

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

Atg5-Independent Sequestration of Ubiquitinated Mycobacteria

(2009) Cathleen A. Collins et al.   PLoS Pathogens

Ordered Assembly of the ESCRT-III Complex on Endosomes Is Required to Sequester Cargo during MVB Formation

(2008) David Teis et al.   DEVELOPMENTAL CELL

Evidence for Pore Formation in Host Cell Membranes by ESX-1-Secreted ESAT-6 and Its Role in Mycobacterium marinum Escape from the Vacuole

(2008) J. Smith et al.   INFECTION AND IMMUNITY

ESCRT factors restrict mycobacterial growth

(2008) J. A. Philips et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helical Structures of ESCRT-III Are Disassembled by VPS4

(2008) S. Lata et al.   SCIENCE

DictyosteliumTom1 Participates to an Ancestral ESCRT-0 Complex

(2008) Cédric Blanc et al.   TRAFFIC