Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophages

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus

(2016) Shoko Nogusa et al.   Cell Host & Microbe

Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis

(2015) D A Rodriguez et al.   CELL DEATH AND DIFFERENTIATION

RIPK1 and NF- B signaling in dying cells determines cross-priming of CD8+ T cells

(2015) N. Yatim et al.   SCIENCE

Targeted Prostaglandin E2 Inhibition Enhances Antiviral Immunity through Induction of Type I Interferon and Apoptosis in Macrophages

(2014) François Coulombe et al.   IMMUNITY

Annexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection

(2014) Fanny Tzelepis et al.   JOURNAL OF CLINICAL INVESTIGATION

NOD2-Deficient Mice Have Impaired Resistance to Mycobacterium tuberculosis Infection through Defective Innate and Adaptive Immunity

(2014) M. Divangahi et al.   JOURNAL OF IMMUNOLOGY

Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

(2014) K. Newton et al.   SCIENCE

Functions of caspase 8: The identified and the mysterious

(2014) Guy S. Salvesen et al.   SEMINARS IN IMMUNOLOGY

TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species

(2013) Francisco J. Roca et al.   CELL

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

The Novel Orally Active Proteasome Inhibitor K-7174 Exerts Anti-myeloma Activityin Vitroandin Vivoby Down-regulating the Expression of Class I Histone Deacetylases

(2013) Jiro Kikuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia

(2013) S J Kim et al.   Cell Death & Disease

Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

(2013) Stephen W.G. Tait et al.   Cell Reports

Efferocytosis Is an Innate Antibacterial Mechanism

(2012) Constance J. Martin et al.   Cell Host & Microbe

Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

(2011) Frank Edlich et al.   CELL

Inhibitor of Nrf2 (INrf2 or Keap1) Protein Degrades Bcl-xL via Phosphoglycerate Mutase 5 and Controls Cellular Apoptosis

(2011) Suryakant K. Niture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme

(2011) Amparo Wolf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

(2011) Maria Feoktistova et al.   MOLECULAR CELL

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

(2011) Tencho Tenev et al.   MOLECULAR CELL

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

(2011) Andrew Oberst et al.   NATURE

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

(2011) N Vanlangenakker et al.   Cell Death & Disease

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

(2010) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis

(2010) S. L. Osborn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

(2010) P. Vandenabeele et al.   Science Signaling

The Type I NADH Dehydrogenase of Mycobacterium tuberculosis Counters Phagosomal NOX2 Activity to Inhibit TNF-α-Mediated Host Cell Apoptosis

(2010) Jessica L. Miller et al.   PLoS Pathogens

Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis

(2009) Zachary T. Schug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

(2008) Francois Gonzalvez et al.   JOURNAL OF CELL BIOLOGY

Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2and LXA4in the induction of macrophage death

(2008) Minjian Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE