Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells

Inflammatory signaling in human tuberculosis granulomas is spatially organized

(2016) Mohlopheni J Marakalala et al.   NATURE MEDICINE

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

(2015) S. M. Irwin et al.   Disease Models & Mechanisms

Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses

(2015) Anne Lenaerts et al.   IMMUNOLOGICAL REVIEWS

The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD

(2015) Jim Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD

(2015) Jim Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes

(2014) Michael Walch et al.   CELL

Lysosomal membrane permeabilization and autophagy blockade contribute to photoreceptor cell death in a mouse model of retinitis pigmentosa

(2014) N Rodríguez-Muela et al.   CELL DEATH AND DIFFERENTIATION

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

(2014) Timothy J. Sargeant et al.   NATURE CELL BIOLOGY

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

A new unifying theory of the pathogenesis of tuberculosis

(2013) Ian M. Orme   TUBERCULOSIS

Intracellular Bacillary Burden Reflects a Burst Size for Mycobacterium tuberculosis In Vivo

(2013) Teresa Repasy et al.   PLoS Pathogens

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

(2012) David M. Tobin et al.   CELL

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

Efferocytosis Is an Innate Antibacterial Mechanism

(2012) Constance J. Martin et al.   Cell Host & Microbe

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

(2012) E. F. Castillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas

(2011) Jackson G. Egen et al.   IMMUNITY

Pathology of post primary tuberculosis of the lung: An illustrated critical review

(2011) Robert L. Hunter   TUBERCULOSIS

Immunopathology of Postprimary Tuberculosis: Increased T-Regulatory Cells and DEC-205-Positive Foamy Macrophages in Cavitary Lesions

(2010) Kerry J. Welsh et al.   Clinical & Developmental Immunology

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

(2010) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

(2010) Samuel M. Behar et al.   NATURE REVIEWS MICROBIOLOGY

Tuberculosis: What We Don't Know Can, and Does, Hurt Us

(2010) D. G. Russell et al.   SCIENCE

Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

(2010) Musa Sani et al.   PLoS Pathogens

How does multiple testing correction work?

(2009) William S Noble   NATURE BIOTECHNOLOGY

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Life on the inside: the intracellular lifestyle of cytosolic bacteria

(2009) Katrina Ray et al.   NATURE REVIEWS MICROBIOLOGY

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

(2009) Clifton E. Barry et al.   NATURE REVIEWS MICROBIOLOGY

Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence

(2008) Huixian Gan et al.   NATURE IMMUNOLOGY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE