Mycobacterium tuberculosisreplicates within necrotic human macrophages

3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy

(2016) Matthew R. G. Russell et al.   JOURNAL OF CELL SCIENCE

Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis

(2016) Thomas R. Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

Postprimary Tuberculosis and Macrophage Necrosis: Is There a Big ConNECtion?

(2016) Ka-Wing Wong et al.   mBio

The innate immune response in human tuberculosis

(2015) Thomas R. Lerner et al.   CELLULAR MICROBIOLOGY

Bacillary replication and macrophage necrosis are determinants of neutrophil recruitment in tuberculosis

(2015) Teresa Repasy et al.   MICROBES AND INFECTION

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Tuberculosis drug discovery in the post-post-genomic era

(2014) Benoit Lechartier et al.   EMBO Molecular Medicine

The evolution of our understanding of macrophages and translation of findings toward the clinic

(2014) Fernando O Martinez et al.   Expert Review of Clinical Immunology

Human genetics of tuberculosis: a long and winding road

(2014) L. Abel et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

“Of Mice and Men”: Arginine Metabolism in Macrophages

(2014) Anita C. Thomas et al.   Frontiers in Immunology

Mycobacterium tuberculosis Exploits Human Interferon γ to Stimulate Macrophage Extracellular Trap Formation and Necrosis

(2013) Ka-Wing Wong et al.   JOURNAL OF INFECTIOUS DISEASES

Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases

(2013) R. J. Thapa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Bacillary Burden Reflects a Burst Size for Mycobacterium tuberculosis In Vivo

(2013) Teresa Repasy et al.   PLoS Pathogens

Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase

(2012) A Degterev et al.   CELL DEATH AND DIFFERENTIATION

IFN-Inducible GTPases in Host Cell Defense

(2012) Bae-Hoon Kim et al.   Cell Host & Microbe

Efferocytosis Is an Innate Antibacterial Mechanism

(2012) Constance J. Martin et al.   Cell Host & Microbe

Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models

(2012) D. C. Lacey et al.   JOURNAL OF IMMUNOLOGY

Linking the Transcriptional Profiles and the Physiological States of Mycobacterium tuberculosis during an Extended Intracellular Infection

(2012) Kyle H. Rohde et al.   PLoS Pathogens

In vitro differentiation of human macrophages with enhanced antimycobacterial activity

(2011) Guillaume Vogt et al.   JOURNAL OF CLINICAL INVESTIGATION

EBImage--an R package for image processing with applications to cellular phenotypes

(2010) G. Pau et al.   BIOINFORMATICS

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

(2010) Samuel M. Behar et al.   NATURE REVIEWS MICROBIOLOGY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Confronting the scientific obstacles to global control of tuberculosis

(2008) Douglas B. Young et al.   JOURNAL OF CLINICAL INVESTIGATION