Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in Aβ oligomer-treated mice
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Gelsemine, a natural alkaloid extracted from Gelsemium elegans Benth. alleviates neuroinflammation and cognitive impairments in Aβ oligomer-treated mice
Authors
Keywords
-
Journal
PSYCHOPHARMACOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-05-04
DOI
10.1007/s00213-020-05522-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Gelsemine and koumine, principal active ingredients of Gelsemium, exhibit mechanical antiallodynia via spinal glycine receptor activation-induced allopregnanolone biosynthesis
- (2019) Rana Muhammad Shoaib et al. BIOCHEMICAL PHARMACOLOGY
- Taxifolin prevents β-amyloid-induced impairments of synaptic formation and deficits of memory via the inhibition of cytosolic phospholipase A2/prostaglandin E2 content
- (2018) Yuanyuan Wang et al. METABOLIC BRAIN DISEASE
- Methyl Salicylate Lactoside Protects Neurons Ameliorating Cognitive Disorder Through Inhibiting Amyloid Beta-Induced Neuroinflammatory Response in Alzheimer’s Disease
- (2018) Jinze Li et al. Frontiers in Aging Neuroscience
- Soluble Aβ1–42 increases the heterogeneity in synaptic vesicle pool size among synapses by suppressing intersynaptic vesicle sharing
- (2018) Daehun Park et al. Molecular Brain
- Isorhynchophylline alleviates learning and memory impairments induced by aluminum chloride in mice
- (2018) Hui-Qin Li et al. Chinese Medicine
- A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
- (2018) Huang Chunhui et al. Jove-Journal of Visualized Experiments
- Isorhynchophylline Treatment Improves the Amyloid-β-Induced Cognitive Impairment in Rats via Inhibition of Neuronal Apoptosis and Tau Protein Hyperphosphorylation
- (2018) Yan-Fang Xian et al. JOURNAL OF ALZHEIMERS DISEASE
- Neuroprotective effect of mogrol against Aβ1-42 -induced memory impairment neuroinflammation and apoptosis in mice
- (2018) Gangling Chen et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Uncaria rhynchophylla ameliorates amyloid beta deposition and amyloid beta-mediated pathology in 5XFAD mice
- (2018) Soo Jung Shin et al. NEUROCHEMISTRY INTERNATIONAL
- Modulation of AβPP and GSK3β by Endoplasmic Reticulum Stress and Involvement in Alzheimer’s Disease
- (2017) Xin-jun Liu et al. JOURNAL OF ALZHEIMERS DISEASE
- Synapsin I phosphorylation is dysregulated by beta-amyloid oligomers and restored by valproic acid
- (2017) Jade Marsh et al. NEUROBIOLOGY OF DISEASE
- Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice
- (2017) Qiaoqiao Shi et al. Science Translational Medicine
- Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
- (2017) Anna Ochalek et al. Alzheimers Research & Therapy
- Amyloid-β Induces Caspase-Dependent Loss of PSD-95 and Synaptophysin Through NMDA Receptors
- (2017) Jinping Liu et al. JOURNAL OF ALZHEIMERS DISEASE
- Sunitinib, a Clinically Used Anticancer Drug, Is a Potent AChE Inhibitor and Attenuates Cognitive Impairments in Mice
- (2016) Ling Huang et al. ACS Chemical Neuroscience
- Functional modulation of glycine receptors by the alkaloid gelsemine
- (2016) Cesar O Lara et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- Acceleration of Amyloidosis by Inflammation in the Amyloid-Beta Marmoset Monkey Model of Alzheimer’s Disease
- (2016) Ingrid H. Philippens et al. JOURNAL OF ALZHEIMERS DISEASE
- Ginsenosides attenuate d-galactose- and AlCl3-inducedspatial memory impairment by restoring the dysfunction of the neurotransmitter systems in the rat model of Alzheimer's disease
- (2016) Yan Zhang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Alzheimer's disease
- (2016) Philip Scheltens et al. LANCET
- Alzheimer’s disease like pathology induced six weeks after aggregated amyloid-beta injection in rats: increased oxidative stress and impaired long-term memory with anxiety-like behavior
- (2016) Sheetal Sharma et al. NEUROLOGICAL RESEARCH
- Gelsemine alleviates both neuropathic pain and sleep disturbance in partial sciatic nerve ligation mice
- (2015) Yu-er Wu et al. ACTA PHARMACOLOGICA SINICA
- Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits
- (2015) Shu-Sheng Jiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin
- (2015) Lan Chang et al. Scientific Reports
- Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease
- (2014) Amy K. Y. Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacological effect of gelsemine on anxiety-like behavior in rat
- (2013) Laurence Meyer et al. BEHAVIOURAL BRAIN RESEARCH
- New insights into the role of glycogen synthase kinase-3 in Alzheimer's disease
- (2013) Miguel Medina et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer’s Disease
- (2012) S. Duke Han et al. Brain Imaging and Behavior
- Effects of koumine, an alkaloid of Gelsemium elegans Benth., on inflammatory and neuropathic pain models and possible mechanism with allopregnanolone
- (2012) Ying Xu et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- The active alkaloids of Gelsemium elegans Benth. are potent anxiolytics
- (2012) Ming Liu et al. PSYCHOPHARMACOLOGY
- Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease
- (2011) B. DaRocha-Souto et al. NEUROBIOLOGY OF DISEASE
- Antitumor activity of two gelsemine metabolites in rat liver microsomes
- (2010) Qing-Chun Zhao et al. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now