Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes

Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis

(2019) Nicholas M. Riley et al.   Nature Communications

Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx

(2019) Leonhard Möckl et al.   DEVELOPMENTAL CELL

Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling

(2019) Junnian Wei et al.   MOLECULAR & CELLULAR PROTEOMICS

PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation

(2018) Thomas B. Davis et al.   Scientific Reports

Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins

(2018) Alexander J Martinko et al.   eLife

Fucosylated Antigens in Cancer: An Alliance toward Tumor Progression, Metastasis, and Resistance to Chemotherapy

(2018) Athanasios Blanas et al.   Frontiers in Oncology

Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression

(2018) Arvindhan Nagarajan et al.   Frontiers in Endocrinology

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

(2018) Angelina V. Vaseva et al.   CANCER CELL

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(2018) Damaris Bausch-Fluck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome

(2018) Kevin K. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTPRF as a novel tumor suppressor through deactivation of ERK1/2 signaling in gastric adenocarcinoma

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B Cell Siglecs–News on Signaling and Its Interplay With Ligand Binding

(2018) Sarah J. Meyer et al.   Frontiers in Immunology

Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors

(2017) Charles L. Dulberger et al.   IMMUNITY

Parallel Comparison of N-Linked Glycopeptide Enrichment Techniques Reveals Extensive Glycoproteomic Analysis of Plasma Enabled by SAX-ERLIC

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Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate

(2017) Rebeca Kawahara et al.   Journal of Proteomics

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Glycoproteomics: A Balance between High-Throughput and In-Depth Analysis

(2017) Yang Yang et al.   TRENDS IN BIOTECHNOLOGY

pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification

(2017) Ming-Qi Liu et al.   Nature Communications

A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression

(2017) Elliot C Woods et al.   eLife

Overexpression of UNC5B in bladder cancer cells inhibits proliferation and reduces the volume of transplantation tumors in nude mice

(2016) Chuize Kong et al.   BMC CANCER

Chemical Glycoproteomics

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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

(2016) Avery D. Posey et al.   IMMUNITY

Evaluation of Different N-Glycopeptide Enrichment Methods for N-Glycosylation Sites Mapping in Mouse Brain

(2016) Chengqian Zhang et al.   JOURNAL OF PROTEOME RESEARCH

K-Ras Activation Induces Differential Sensitivity to Sulfur Amino Acid Limitation and Deprivation and to Oxidative and Anti-Oxidative Stress in Mouse Fibroblasts

(2016) Gaia De Sanctis et al.   PLoS One

Precision glycocalyx editing as a strategy for cancer immunotherapy

(2016) Han Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

N-acetylgalactosaminyltransferases in cancer

(2016) Muhammad Ramzan Manwar Hussain et al.   Oncotarget

Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface

(2016) Xiaoying Ye et al.   Oncotarget

LAMC2 enhances the metastatic potential of lung adenocarcinoma

(2015) Y W Moon et al.   CELL DEATH AND DIFFERENTIATION

Update on Mucin-1 immunotherapy in cancer: a clinical perspective

(2015) Gareth Rivalland et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Contribution of rare germline copy number variations and common susceptibility loci in Lynch syndrome patients negative for mutations in the mismatch repair genes

(2015) Rolando A.R. Villacis et al.   INTERNATIONAL JOURNAL OF CANCER

Galectin-3 Binding Protein and Galectin-1 Interaction in Breast Cancer Cell Aggregation and Metastasis

(2015) Tzu-Wen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression

(2015) Stephanie Holst et al.   MOLECULAR & CELLULAR PROTEOMICS

Oncogene-induced senescence underlies the mutual exclusive nature of oncogenic KRAS and BRAF

(2015) J Cisowski et al.   ONCOGENE

Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors

(2015) A. Morello et al.   Cancer Discovery

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A Mass Spectrometric-Derived Cell Surface Protein Atlas

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Evaluation of MCF10A as a Reliable Model for Normal Human Mammary Epithelial Cells

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Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells

(2014) Katharina Leithner et al.   BMC CANCER

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The cancer glycocalyx mechanically primes integrin-mediated growth and survival

(2014) Matthew J. Paszek et al.   NATURE

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Heparan sulfate signaling in cancer

(2014) Erik H. Knelson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Linking Tumor Mutations to Drug Responses via a Quantitative Chemical–Genetic Interaction Map

(2014) Maria M. Martins et al.   Cancer Discovery

The Roles of CD73 in Cancer

(2014) Zhao-wei Gao et al.   Biomed Research International

Altered Glycosylation in Tumours Focused to Cancer Diagnosis

(2013) Rosa Peracaula et al.   DISEASE MARKERS

GALNT11 as a new molecular marker in chronic lymphocytic leukemia

(2013) M.G. Libisch et al.   GENE

Up to 15-year clinical follow-up of a pilot Phase III immunotherapy study in stage II breast cancer patients using oxidized mannan–MUC1

(2013) Stamatis Vassilaros et al.   Immunotherapy

Differentiation of Cancer Cell Origin and Molecular Subtype by Plasma Membrane N-Glycan Profiling

(2013) Serenus Hua et al.   JOURNAL OF PROTEOME RESEARCH

The Expression of CD10 and CD15 Is Progressively Increased during Colorectal Cancer Development

(2013) Tae Jung Jang et al.   Korean Journal of Pathology

Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion

(2013) Jason E Hudak et al.   Nature Chemical Biology

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Protein kinase Cδ is required for ErbB2-driven mammary gland tumorigenesis and negatively correlates with prognosis in human breast cancer

(2013) B L Allen-Petersen et al.   ONCOGENE

Overexpression of Arginine Transporter CAT-1 Is Associated with Accumulation of L-Arginine and Cell Growth in Human Colorectal Cancer Tissue

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The FBI1/Akirin2 Target Gene, BCAM, Acts as a Suppressive Oncogene

(2013) Hirotada Akiyama et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Evaluating cell lines as tumour models by comparison of genomic profiles

(2013) Silvia Domcke et al.   Nature Communications

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Identifying cancer biomarkers by mass spectrometry-based glycomics

(2012) Yehia Mechref et al.   ELECTROPHORESIS

Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via  -catenin signaling

(2012) T. Stoyanova et al.   GENES & DEVELOPMENT

N-glycosylation of Colorectal Cancer Tissues

(2012) Crina I. A. Balog et al.   MOLECULAR & CELLULAR PROTEOMICS

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Glycans as cancer biomarkers

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Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Extensive Determination of Glycan Heterogeneity Reveals an Unusual Abundance of High Mannose Glycans in Enriched Plasma Membranes of Human Embryonic Stem Cells

(2011) Hyun Joo An et al.   MOLECULAR & CELLULAR PROTEOMICS

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Culture medium, gas atmosphere and MAPK inhibition affect regulation of RNA-binding protein targets during mouse preimplantation development

(2011) Michele D Calder et al.   REPRODUCTION

Defining the transcriptome and proteome in three functionally different human cell lines

(2010) Emma Lundberg et al.   Molecular Systems Biology

Membrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cells

(2010) S Bafna et al.   ONCOGENE

Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency

(2010) Rodolfo Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms

(2010) Erik Wallin et al.   PROTEIN SCIENCE

Normal stem cells and cancer stem cells: similar and different

(2010) Mark Shackleton   SEMINARS IN CANCER BIOLOGY

Therapeutic antibodies: successes, limitations and hopes for the future

(2009) Patrick Chames et al.   BRITISH JOURNAL OF PHARMACOLOGY

Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: Clues in the ongoing search for new tumor markers

(2009) Reiji Kannagi et al.   CANCER SCIENCE

The Role of Podocalyxin in Health and Disease

(2009) J. S. Nielsen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins

(2009) Bernd Wollscheid et al.   NATURE BIOTECHNOLOGY

The Universal Protein Resource (UniProt) in 2010

(2009)   NUCLEIC ACIDS RESEARCH