Northern Sea Cucumber (Cucumaria frondosa): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector

Effects of collagenase type I on the structural features of collagen fibres from sea cucumber (Stichopus japonicus) body wall

(2019) Yu-xin Liu et al.   FOOD CHEMISTRY

Frondanol, a Nutraceutical Extract from Cucumaria frondosa, Attenuates Colonic Inflammation in a DSS-Induced Colitis Model in Mice

(2018) Sandeep Subramanya et al.   Marine Drugs

The Anti-Cancer Effects of Frondoside A

(2018) Thomas E. Adrian et al.   Marine Drugs

Anti-aging effect of sea cucumber ( Cucumaria frondosa ) hydrolysate on fruit flies and d -galactose-induced aging mice

(2018) Lianzhu Lin et al.   Journal of Functional Foods

Bioactive compounds and biological functions of sea cucumbers as potential functional foods

(2018) Cheng Xu et al.   Journal of Functional Foods

Effects of endogenous cysteine proteinases on structures of collagen fibres from dermis of sea cucumber ( Stichopus japonicus )

(2017) Yu-Xin Liu et al.   FOOD CHEMISTRY

Antioxidant properties of Korean major persimmon (Diospyros kaki) leaves

(2017) Abul Hossain et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties

(2017) Muhammad Abdul Mojid Mondol et al.   Marine Drugs

Rapid modulation of lipid metabolism in C57BL/6J mice induced by eicosapentaenoic acid-enriched phospholipid from Cucumaria frondosa

(2017) Lingyu Zhang et al.   Journal of Functional Foods

Influence of diet on growth, reproduction and lipid and fatty acid composition in the sea cucumber Cucumaria frondosa

(2016) Bruno L Gianasi et al.   AQUACULTURE RESEARCH

Antithrombotic activities of fucosylated chondroitin sulfates and their depolymerized fragments from two sea cucumbers

(2016) Xiaoxiao Liu et al.   CARBOHYDRATE POLYMERS

Experimental test of optimal holding conditions for live transport of temperate sea cucumbers

(2016) Bruno L. Gianasi et al.   FISHERIES RESEARCH

Long-chain bases from Cucumaria frondosa inhibit adipogenesis and regulate lipid metabolism in 3T3-L1 adipocytes

(2016) Yingying Tian et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Fucoidan from Cucumaria frondosa Inhibits Pancreatic Islets Apoptosis Through Mitochondrial Signaling Pathway in Insulin Resistant Mice

(2016) Shiwei Hu et al.   FOOD SCIENCE AND TECHNOLOGY RESEARCH

Effect of Enzyme Type on the Antioxidant Activities and Functional Properties of Enzymatic Hydrolysates from Sea Cucumber (Cucumaria frondosa) Viscera

(2016) Mingyan Yan et al.   Journal of Aquatic Food Product Technology

Fucoidan from sea cucumber Cucumaria frondosa exhibits anti-hyperglycemic effects in insulin resistant mice via activating the PI3K/PKB pathway and GLUT4

(2016) Yiming Wang et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Structure of Sphingolipids From Sea Cucumber Cucumaria frondosa and Structure-Specific Cytotoxicity Against Human HepG2 Cells

(2016) Zicai Jia et al.   LIPIDS

Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer

(2016) Jasem Al Shemaili et al.   Marine Drugs

In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa

(2016) Xiaoxiao Liu et al.   MOLECULES

Interfibrillar stiffening of echinoderm mutable collagenous tissue demonstrated at the nanoscale

(2016) Jingyi Mo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physicochemical properties and antioxidant activities of two fucosylated chondroitin sulfate from sea cucumber Acaudina molpadioidea and Holothuria nobilis

(2016) Shanmei Zou et al.   PROCESS BIOCHEMISTRY

Improved Innate Immune Responses by Frondanol A5, a Sea Cucumber Extract, Prevent Intestinal Tumorigenesis

(2015) N. B. Janakiram et al.   Cancer Prevention Research

The materials science of collagen

(2015) Vincent R. Sherman et al.   Journal of the Mechanical Behavior of Biomedical Materials

Sea Cucumbers Metabolites as Potent Anti-Cancer Agents

(2015) Naveena Janakiram et al.   Marine Drugs

Therapies from Fucoidan: An Update

(2015) Janet Fitton et al.   Marine Drugs

Anticancer Activity of Sea Cucumber Triterpene Glycosides

(2015) Dmitry Aminin et al.   Marine Drugs

Fucoidan and Cancer: A Multifunctional Molecule with Anti-Tumor Potential

(2015) Farzaneh Atashrazm et al.   Marine Drugs

In vitro antiviral activities of enzymatic hydrolysates extracted from byproducts of the Atlantic holothurian Cucumaria frondosa

(2015) Ludovic Tripoteau et al.   PROCESS BIOCHEMISTRY

Antitumour activity of EPA-enriched phospholipids liposomes against S180 ascitic tumour-bearing mice

(2015) Lei Du et al.   Journal of Functional Foods

Collagen and Gelatin

(2015) Dasong Liu et al.   Annual Review of Food Science and Technology

The WNT/β-catenin pathway is involved in the anti-adipogenic activity of cerebrosides from the sea cucumber Cucumaria frondosa

(2015) Hui Xu et al.   Food & Function

Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer

(2014) J. Al Shemaili et al.   EUROPEAN JOURNAL OF CANCER

Purification, Characterization, cDNA Cloning and In Vitro Expression of a Serine Proteinase from the Intestinal Tract of Sea Cucumber (Stichopus japonicus) with Collagen Degradation Activity

(2014) Long-Jie Yan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chondroitin sulfate: extraction, purification, microbial and chemical synthesis

(2014) Yu-gang Shi et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Cytotoxic and Apoptosis-Inducing Activity of Triterpene Glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 Cells

(2014) Juanjuan Wang et al.   Marine Drugs

Separation, purification, anticoagulant activity and preliminary structural characterization of two sulfated polysaccharides from sea cucumber Acaudina molpadioidea and Holothuria nobilis

(2014) Xiaodi Dong et al.   PROCESS BIOCHEMISTRY

Fucosylated chondroitin sulphate from sea cucumber inhibits high-fat-sucrose diet-induced apoptosis in mouse pancreatic islets via down-regulating mitochondrial signaling pathway

(2014) Shiwei Hu et al.   Journal of Functional Foods

Fucosylated Chondroitin Sulfate from Sea Cucumber in Combination with Rosiglitazone Improved Glucose Metabolism in the Liver of the Insulin-Resistant Mice

(2013) Shiwei HU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Eicosapentaenoic acid-enriched phosphatidylcholine isolated from Cucumaria frondosa exhibits anti-hyperglycemic effects via activating phosphoinositide 3-kinase/protein kinase B signal pathway

(2013) Shiwei Hu et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Isolation of cytotoxic glucoerebrosides and long-chain bases from sea cucumber Cucumaria frondosa using high speed counter-current chromatography

(2013) Jie Xu et al.   Journal of Oleo Science

The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice

(2013) Feng-Juan Wu et al.   NEUROCHEMISTRY INTERNATIONAL

Frondoside A Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis

(2013) Samir Attoub et al.   PLoS One

Sequence determination and anticoagulant and antithrombotic activities of a novel sulfated fucan isolated from the sea cucumber Isostichopus badionotus

(2012) Shiguo Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Depolymerization of fucosylated chondroitin sulfate from sea cucumber, Pearsonothuria graeffei, via 60Co irradiation

(2012) Nian Wu et al.   CARBOHYDRATE POLYMERS

Protective effect of sea cucumber (Acaudina molpadioides) fucoidan against ethanol-induced gastric damage

(2012) Yanchao Wang et al.   FOOD CHEMISTRY

Fractionation and characterization of antioxidant peptides derived from barley glutelin by enzymatic hydrolysis

(2012) Yichen Xia et al.   FOOD CHEMISTRY

Frondoside A has an anti-invasive effect by inhibiting TPA-induced MMP-9 activation via NF-κB and AP-1 signaling in human breast cancer cells

(2012) SUN YOUNG PARK et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Chondroitin sulfate extraction from broiler chicken cartilage by tissue autolysis

(2012) Anchalee Srichamroen et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

A Review of the Northern Sea CucumberCucumaria frondosa(Gunnerus, 1767) as a Potential Aquaculture Species

(2012) Emily J. Nelson et al.   REVIEWS IN FISHERIES SCIENCE

Algal fucoidan: structural and size-dependent bioactivities and their perspectives

(2011) V. K. Morya et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2

(2011) Xinrong Ma et al.   BREAST CANCER RESEARCH AND TREATMENT

Frondoside A inhibits human breast cancer cell survival, migration, invasion and the growth of breast tumor xenografts

(2011) Nadia Al Marzouqi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Functional and bioactive properties of collagen and gelatin from alternative sources: A review

(2011) M.C. Gómez-Guillén et al.   FOOD HYDROCOLLOIDS

Jewel of the seabed: sea cucumbers as nutritional and drug candidates

(2011) Peck Loo Kiew et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review

(2011) Sara Bordbar et al.   Marine Drugs

Chemopreventive Effects of Frondanol A5, a Cucumaria frondosa Extract, against Rat Colon Carcinogenesis and Inhibition of Human Colon Cancer Cell Growth

(2010) N. B. Janakiram et al.   Cancer Prevention Research

Comparison of structures and anticoagulant activities of fucosylated chondroitin sulfates from different sea cucumbers

(2010) Shiguo Chen et al.   CARBOHYDRATE POLYMERS

Antitumor activity of the immunomodulatory lead Cumaside

(2010) D.L. Aminin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Nutritional composition and antioxidant properties of protein hydrolysates prepared from echinoderm byproducts

(2010) Jean Mamelona et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Proximate composition and nutritional profile of by-products from green urchin and Atlantic sea cucumber processing plants

(2010) Jean Mamelona et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Chemical composition and nutritional quality of sea cucumbers

(2010) Jing Wen et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Anti-Pancreatic Cancer Effects of a Polar Extract From the Edible Sea Cucumber, Cucumaria frondosa

(2010) Alexandra B. Roginsky et al.   PANCREAS

Review of the Apoptosis Pathways in Pancreatic Cancer and the Anti-apoptotic Effects of the Novel Sea Cucumber Compound, Frondoside A

(2009) X. Li et al.   Annals of the New York Academy of Sciences

Differential effects of triterpene glycosides, frondoside A and cucumarioside A2-2 isolated from sea cucumbers on caspase activation and apoptosis of human leukemia cells

(2009) Jun-O Jin et al.   FEBS LETTERS

Biochemical properties of alligator (Alligator mississippiensis) bone collagen

(2008) Ashley Wood et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Recent Advances in the Structural Study of Functional Chondroitin Sulfate and Dermatan Sulfate in Health and Disease

(2008) Christina Malavaki et al.   CONNECTIVE TISSUE RESEARCH

Antioxidant activity of peptides isolated from alfalfa leaf protein hydrolysate

(2008) Zhengjun Xie et al.   FOOD CHEMISTRY

Immunomodulatory Properties of Frondoside A, a Major Triterpene Glycoside from the North Atlantic Commercially Harvested Sea Cucumber Cucumaria frondosa

(2008) D.L. Aminin et al.   JOURNAL OF MEDICINAL FOOD