The Anti-Cancer Effects of Frondoside A

Curcumin attenuates collagen-induced inflammatory response through the “gut-brain axis”

(2018) Yannong Dou et al.   Journal of Neuroinflammation

Mechanisms of cancer cell killing by sea cucumber-derived compounds

(2017) Teresa Liliana Wargasetia et al.   INVESTIGATIONAL NEW DRUGS

Frondoside A induces AIF-associated caspase-independent apoptosis in Burkitt lymphoma cells

(2017) Sergey A. Dyshlovoy et al.   LEUKEMIA & LYMPHOMA

Frondoside A potentiates the effects of conventional therapeutic agents in acute leukemia

(2017) F.H. Sajwani et al.   LEUKEMIA RESEARCH

Anticancer and cancer preventive compounds from edible marine organisms

(2017) Marta Correia-da-Silva et al.   SEMINARS IN CANCER BIOLOGY

Clinicopathological signature of p21-activated kinase 1 in prostate cancer and its regulation of proliferation and autophagy via the mTOR signaling pathway

(2017) Zhanyu Wang et al.   Oncotarget

The marine triterpene glycoside frondoside A exhibits activity in vitro and in vivo in prostate cancer

(2016) Sergey A. Dyshlovoy et al.   INTERNATIONAL JOURNAL OF CANCER

Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer

(2016) Jasem Al Shemaili et al.   Marine Drugs

Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the “Supply Problem”

(2016) Nelson Gomes et al.   Marine Drugs

Systems pharmacology-based drug discovery for marine resources: An example using sea cucumber (Holothurians)

(2015) Yingying Guo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Sea Cucumbers Metabolites as Potent Anti-Cancer Agents

(2015) Naveena Janakiram et al.   Marine Drugs

Anticancer Activity of Sea Cucumber Triterpene Glycosides

(2015) Dmitry Aminin et al.   Marine Drugs

Bioactive Sulfated Saponins from Sea Cucumber Holothuria moebii

(2015) Siran Yu et al.   PLANTA MEDICA

Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer

(2014) J. Al Shemaili et al.   EUROPEAN JOURNAL OF CANCER

Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers

(2014) Joo-In Park et al.   Frontiers in Chemistry

Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties

(2013) Namita Kundu et al.   BREAST CANCER RESEARCH AND TREATMENT

Triterpenoids of Marine Origin as Anti-Cancer Agents

(2013) Yong-Xin Li et al.   MOLECULES

Studies on the mechanism of action of frondoside A in pancreatic cancer

(2013) J. Al Shemaili et al.   PANCREATOLOGY

Frondoside A Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis

(2013) Samir Attoub et al.   PLoS One

Frondoside A has an anti-invasive effect by inhibiting TPA-induced MMP-9 activation via NF-κB and AP-1 signaling in human breast cancer cells

(2012) SUN YOUNG PARK et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Modulation of Host Natural Killer Cell Functions in Breast Cancer via Prostaglandin E2 Receptors EP2 and EP4

(2012) Dawn M. Holt et al.   JOURNAL OF IMMUNOTHERAPY

Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2

(2011) Xinrong Ma et al.   BREAST CANCER RESEARCH AND TREATMENT

Frondoside A inhibits human breast cancer cell survival, migration, invasion and the growth of breast tumor xenografts

(2011) Nadia Al Marzouqi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Review of the Apoptosis Pathways in Pancreatic Cancer and the Anti-apoptotic Effects of the Novel Sea Cucumber Compound, Frondoside A

(2009) X. Li et al.   Annals of the New York Academy of Sciences

Differential effects of triterpene glycosides, frondoside A and cucumarioside A2-2 isolated from sea cucumbers on caspase activation and apoptosis of human leukemia cells

(2009) Jun-O Jin et al.   FEBS LETTERS

Immunomodulatory effects of holothurian triterpene glycosides on mammalian splenocytes determined by mass spectrometric proteome analysis

(2009) Dmitri L. Aminin et al.   Journal of Proteomics

Immunomodulatory Properties of Frondoside A, a Major Triterpene Glycoside from the North Atlantic Commercially Harvested Sea Cucumber Cucumaria frondosa

(2008) D.L. Aminin et al.   JOURNAL OF MEDICINAL FOOD

Constituents of the Sea CucumberCucumaria okhotensis.Structures of Okhotosides B1–B3and Cytotoxic Activities of Some Glycosides from this Species⊥

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