Anticancer Activity of Sea Cucumber Triterpene Glycosides

Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer

(2014) J. Al Shemaili et al.   EUROPEAN JOURNAL OF CANCER

Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers

(2014) Joo-In Park et al.   Frontiers in Chemistry

Antitumor Activity of Cucumarioside A2-2

(2013) E.S. Menchinskaya et al.   CHEMOTHERAPY

Frondoside A Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis

(2013) Samir Attoub et al.   PLoS One

Stichoposide C Induces Apoptosis through the Generation of Ceramide in Leukemia and Colorectal Cancer Cells and Shows In Vivo Antitumor Activity

(2012) S.-H. Yun et al.   CLINICAL CANCER RESEARCH

Frondoside A has an anti-invasive effect by inhibiting TPA-induced MMP-9 activation via NF-κB and AP-1 signaling in human breast cancer cells

(2012) SUN YOUNG PARK et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2

(2011) Xinrong Ma et al.   BREAST CANCER RESEARCH AND TREATMENT

The triterpene glycosides of Holothuria forskali: usefulness and efficiency as a chemical defense mechanism against predatory fish

(2011) S. Van Dyck et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

In vitro and in vivo anti-tumour activities of echinoside A and ds-echinoside A from Pearsonothuria graeffei

(2011) Qin Zhao et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions

(2011) Qin Zhao et al.   Journal of Zhejiang University-SCIENCE B

High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review

(2011) Sara Bordbar et al.   Marine Drugs

The saponins – polar isoprenoids with important and diverse biological activities

(2011) Anne Osbourn et al.   NATURAL PRODUCT REPORTS

Chemopreventive Effects of Frondanol A5, a Cucumaria frondosa Extract, against Rat Colon Carcinogenesis and Inhibition of Human Colon Cancer Cell Growth

(2010) N. B. Janakiram et al.   Cancer Prevention Research

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells

(2010) Samir Attoub et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antitumor activity of the immunomodulatory lead Cumaside

(2010) D.L. Aminin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Differential Effects of Sulfated Triterpene Glycosides, Holothurin A1, and 24-Dehydroechinoside A, on Antimetastasic Activity via Regulation of the MMP-9 Signal Pathway

(2010) Qin Zhao et al.   JOURNAL OF FOOD SCIENCE

Qualitative and Quantitative Saponin Contents in Five Sea Cucumbers from the Indian Ocean

(2010) Séverine Van Dyck et al.   Marine Drugs

Anti-Pancreatic Cancer Effects of a Polar Extract From the Edible Sea Cucumber, Cucumaria frondosa

(2010) Alexandra B. Roginsky et al.   PANCREAS

Saponins as cytotoxic agents: a review

(2010) Irma Podolak et al.   PHYTOCHEMISTRY REVIEWS

Cytotoxic Holostane-Type Triterpene Glycosides from the Sea CucumberPentacta quadrangularis

(2010) Hua Han et al.   PLANTA MEDICA

Echinoside A, a new marine-derived anticancer saponin, targets topoisomerase2  by unique interference with its DNA binding and catalytic cycle

(2009) M. Li et al.   ANNALS OF ONCOLOGY

Review of the Apoptosis Pathways in Pancreatic Cancer and the Anti-apoptotic Effects of the Novel Sea Cucumber Compound, Frondoside A

(2009) X. Li et al.   Annals of the New York Academy of Sciences

Differential effects of triterpene glycosides, frondoside A and cucumarioside A2-2 isolated from sea cucumbers on caspase activation and apoptosis of human leukemia cells

(2009) Jun-O Jin et al.   FEBS LETTERS

Argusides D and E, Two New Cytotoxic Triterpene Glycosides from the Sea CucumberBohadschia argusJaeger

(2008) Bao-Shu Liu et al.   CHEMISTRY & BIODIVERSITY

Antiproliferative, Cytotoxic and Hemolytic Activities of a Triterpene Glycoside from Psolus patagonicus and Its Desulfated Analog

(2008) Valeria P. Careaga et al.   CHEMOTHERAPY

Constituents of the Sea CucumberCucumaria okhotensis.Structures of Okhotosides B1–B3and Cytotoxic Activities of Some Glycosides from this Species⊥

(2008) Alexandra S. Silchenko et al.   JOURNAL OF NATURAL PRODUCTS

Synaptosides A and A1, Triterpene Glycosides from the Sea CucumberSynapta maculataContaining 3-O-Methylglucuronic Acid and Their Cytotoxic Activity against Tumor Cells

(2008) Sergey A. Avilov et al.   JOURNAL OF NATURAL PRODUCTS