Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53

Epigallocatechin Gallate Prevents Mitochondrial Impairment and Cell apoptosis by Regulating miR-30a/p53 Axis

(2019) Chan Zhang et al.   PHYTOMEDICINE

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

(2019) Yang Li et al.   CELL DEATH AND DIFFERENTIATION

Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy

(2019) Jin Wen et al.   PHARMACOLOGICAL RESEARCH

Delivery of mitochondriotropic doxorubicin derivatives using self-assembling hyaluronic acid nanocarriers in doxorubicin-resistant breast cancer

(2018) Hui-na Liu et al.   ACTA PHARMACOLOGICA SINICA

CXCL10-induced IL-9 promotes liver fibrosis via Raf/MEK/ERK signaling pathway

(2018) Xiaoyun Guo et al.   BIOMEDICINE & PHARMACOTHERAPY

Scoparone prevents IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through the PI3K/Akt/NF-κB pathway

(2018) Chao Lu et al.   BIOMEDICINE & PHARMACOTHERAPY

The tumor suppressor protein p53 and the ferroptosis network

(2018) Rui Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ilex asprella aqueous extracts exert in vivo anti-inflammatory effects by regulating the NF-κB, JAK2/STAT3, and MAPK signaling pathways

(2018) Xinyao Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Berberine protects renal tubular cells against hypoxia/reoxygenation injury via the Sirt1/p53 pathway

(2018) Yuanbang Lin et al.   Journal of Natural Medicines

Role of p-MKK7 in myricetin-induced protection against intestinal ischemia/reperfusion injury

(2018) Yuchao Sun et al.   PHARMACOLOGICAL RESEARCH

miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1

(2018) Liwei Liu et al.   Cell Death & Disease

Ginsenoside Rb1 protects against spinal cord ischemia-reperfusion injury in rats by downregulating the Bax/Bcl-2 ratio and caspase-3 and p-Ask-1 levels

(2018) Dongxu Zhao et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

AIF promotes a JNK1-mediated cadherin switch independently of respiratory chain stabilization

(2018) Andrew J. Scott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-κB cytokine pathway

(2018) Xiao-Qian Li et al.   Journal of Neuroinflammation

Protective effects of curcumin against ischemia-reperfusion injury in the liver

(2018) Kowsar Bavarsad et al.   PHARMACOLOGICAL RESEARCH

Protective effect of cinnamaldehyde against glutamate-induced oxidative stress and apoptosis in PC12 cells

(2017) Chao Lv et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MiR-146a protects small intestine against ischemia/reperfusion injury by down-regulating TLR4/TRAF6/NF-κB pathway

(2017) Xuemei He et al.   JOURNAL OF CELLULAR PHYSIOLOGY

6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling

(2017) Yanli Li et al.   PHARMACOLOGICAL RESEARCH

Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice

(2017) Shaowei Li et al.   PLoS One

p-JAK2 plays a key role in catalpol-induced protection against rat intestinal ischemia/reperfusion injury

(2017) Mengqiao Lian et al.   RSC Advances

Antioxidant, Antiapoptotic and Inflammatory Effects of Interleukin-18 Binding Protein on Kidney Damage Induced by Hepatic Ischemia Reperfusion

(2016) Yucel Gonul et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

(2016) Andreas C. Joerger et al.   Annual Review of Biochemistry

miR-34a-5p Inhibition Alleviates Intestinal Ischemia/Reperfusion-Induced Reactive Oxygen Species Accumulation and Apoptosis via Activation of SIRT1 Signaling

(2016) Guangzhi Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury

(2016) Francesco Bellanti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Remote ischemic postconditioning protects against renal ischemia/reperfusion injury by activation of T-LAK-cell-originated protein kinase (TOPK)/PTEN/Akt signaling pathway mediated anti-oxidation and anti-inflammation

(2016) Sumin Gao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cinnamaldehyde Characterization as an Antibacterial Agent toward E. coli Metabolic Profile Using 96-Blade Solid-Phase Microextraction Coupled to Liquid Chromatography–Mass Spectrometry

(2016) Fatemeh Mousavi et al.   JOURNAL OF PROTEOME RESEARCH

Trans-Cinnamaldehyde, An Essential Oil in Cinnamon Powder, Ameliorates Cerebral Ischemia-Induced Brain Injury via Inhibition of Neuroinflammation Through Attenuation of iNOS, COX-2 Expression and NFκ-B Signaling Pathway

(2016) Yuh-Fung Chen et al.   NEUROMOLECULAR MEDICINE

The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress

(2016) Olga Krupkova et al.   Oxidative Medicine and Cellular Longevity

Finding an ethical path forward for mitochondrial replacement

(2016) A. B. Claiborne et al.   SCIENCE

MicroRNA-682-mediated downregulation of PTEN in intestinal epithelial cells ameliorates intestinal ischemia–reperfusion injury

(2016) Z Liu et al.   Cell Death & Disease

Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition

(2016) Hyung-Joon Kwon et al.   Nature Communications

TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene

(2016) Jun-Ming Liao et al.   Scientific Reports

Tumor-Suppressor Functions of the TP53 Pathway

(2016) Brandon J. Aubrey et al.   Cold Spring Harbor Perspectives in Medicine

Cinnamaldehyde and allopurinol reduce fructose-induced cardiac inflammation and fibrosis by attenuating CD36-mediated TLR4/6-IRAK4/1 signaling to suppress NLRP3 inflammasome activation

(2016) Lin-Lin Kang et al.   Scientific Reports

Protective effects of ginsenoside Rg1 on intestinal ischemia/reperfusion injury-induced oxidative stress and apoptosis via activation of the Wnt/β-catenin pathway

(2016) Guo Zu et al.   Scientific Reports

RhoA enhances store-operated Ca2+ entry and intestinal epithelial restitution by interacting with TRPC1 after wounding

(2015) Hee Kyoung Chung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway

(2015) Hyo Jeong Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anti-inflammatory Effect of Cinnamaldehyde in Helicobacter pylori Induced Gastric Inflammation

(2015) Jibran Sualeh Muhammad et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cell death decision by p53 via control of the mitochondrial membrane

(2015) Nurmaa Dashzeveg et al.   CANCER LETTERS

Protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ROS-mediated NF-κB and P53 signaling pathways

(2015) Yassine Chtourou et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Rapamycin Improves Mortality Following Intestinal Ischemia-Reperfusion via the Inhibition of Remote Lung Inflammation in Mice

(2015) Takaya Iida et al.   DIGESTION

Effects of cinnamaldehyde on Escherichia coli and Staphylococcus aureus membrane

(2015) Suxia Shen et al.   FOOD CONTROL

Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis

(2015) Ariele Viacava Follis et al.   MOLECULAR CELL

Cell shape and the microenvironment regulate nuclear translocation of NF- B in breast epithelial and tumor cells

(2015) J. E. Sero et al.   Molecular Systems Biology

Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the JNK and p38 signaling pathways

(2015) Xiao-Jing Zhang et al.   VASCULAR PHARMACOLOGY

Efficacy and Safety of Tranexamic Acid in Bilateral Total Knee Replacement: A Meta-Analysis and Systematic Review

(2015) Peiheng He et al.   MEDICAL SCIENCE MONITOR

Mitochondrial Respiration in Insulin-Producing β-Cells: General Characteristics and Adaptive Effects of Hypoxia

(2015) Ingrid K. Hals et al.   PLoS One

Cooperative interactions between p53 and NFκB enhance cell plasticity

(2015) Alessandra Bisio et al.   Oncotarget

Simultaneous determination of cinnamaldehyde and its metabolite in rat tissues by gas chromatography-mass spectrometry

(2014) Hang Zhao et al.   BIOMEDICAL CHROMATOGRAPHY

Beneficial Antioxidative and Antiperoxidative Effect of Cinnamaldehyde Protect Streptozotocin-Induced Pancreatic β-Cells Damage in Wistar Rats

(2014) P. Subash-Babu et al.   Biomolecules & Therapeutics

Protective Effect of Intestinal Ischemic Preconditioning on Ischemia Reperfusion-Caused Lung Injury in Rats

(2014) Zhidong Wang et al.   INFLAMMATION

Catalpol provides protective effects against cerebral ischaemia/reperfusion injury in gerbils

(2014) Yan-ru Liu et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Selective killing of lung cancer cells by miRNA-506 molecule through inhibiting NF-κB p65 to evoke reactive oxygen species generation and p53 activation

(2014) M Yin et al.   ONCOGENE

Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation

(2013) Jing Guo et al.   ATHEROSCLEROSIS

Effect of berberine on cell cycle arrest and cell survival during cerebral ischemia and reperfusion and correlations with p53/cyclin D1 and PI3K/Akt

(2013) Yu-Shuang Chai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effects of cinnamic acid and cinnamic aldehyde on isoproterenol-induced acute myocardial ischemia in rats

(2013) Fan Song et al.   JOURNAL OF ETHNOPHARMACOLOGY

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in glioma

(2013) Ridwan Alam et al.   NEURO-ONCOLOGY

Propofol prevents cerebral ischemia-triggered autophagy activation and cell death in the rat hippocampus through the NF-κB/p53 signaling pathway

(2013) D.R. Cui et al.   NEUROSCIENCE

Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice

(2013) Jung Eun Kim et al.   PLoS One

Effective Identification of Akt Interacting Proteins by Two-Step Chemical Crosslinking, Co-Immunoprecipitation and Mass Spectrometry

(2013) Bill X. Huang et al.   PLoS One

Identification of NCF2/p67phox as a novel p53 target gene

(2012) Dafne Italiano et al.   CELL CYCLE

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Involvement of NF-κB and Bcl2/Bax signaling pathways in the apoptosis of MCF7 cells induced by a xanthone compound Pyranocycloartobiloxanthone A

(2012) Syam Mohan et al.   PHYTOMEDICINE

Massage Therapy Attenuates Inflammatory Signaling After Exercise-Induced Muscle Damage

(2012) J. D. Crane et al.   Science Translational Medicine

Nucleolar NF-κB/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin

(2011) N Khandelwal et al.   CELL DEATH AND DIFFERENTIATION

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism

(2010) Prashanth Ak et al.   FASEB JOURNAL

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

(2010) D Meley et al.   Cell Death & Disease

Somatostatin Limits Intestinal Ischemia-Reperfusion Injury in Macaques via Suppression of TLR4-NF-κB Cytokine Pathway

(2009) Hao Wu et al.   JOURNAL OF GASTROINTESTINAL SURGERY

The p53 family and programmed cell death

(2008) E C Pietsch et al.   ONCOGENE

Inhibition of the Rho/ROCK pathway reduces apoptosis during transplantation of embryonic stem cell-derived neural precursors

(2007) Masaomi Koyanagi et al.   JOURNAL OF NEUROSCIENCE RESEARCH