Identification of NCF2/p67phox as a novel p53 target gene

p53, ROS and senescence in the control of aging

(2016) Arnaud Vigneron et al.   Aging-US

The NADPH Oxidase Nox4 and Aging in the Heart

(2016) Tetsuro Ago et al.   Aging-US

Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection

(2016) Ara B. Hwang et al.   Aging-US

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress

(2016) Ozkan Ozden et al.   Aging-US

The critical role of catalase in prooxidant and antioxidant function of p53

(2012) M Y Kang et al.   CELL DEATH AND DIFFERENTIATION

Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stresses

(2012) S Lee et al.   CELL DEATH AND DIFFERENTIATION

hnRNP Q regulates translation of p53 in normal and stress conditions

(2012) D-Y Kim et al.   CELL DEATH AND DIFFERENTIATION

DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway

(2012) M A Kang et al.   Cell Death & Disease

Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy

(2012) Weiqin Lu et al.   PLOS BIOLOGY

Polyploidy and dysregulated ROS signaling

(2011) Siobhan E. Craige et al.   CELL CYCLE

Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy

(2011) Donald McCrann et al.   CELL CYCLE

Mitochondrial complex I: A central regulator of the aging process

(2011) Rhoda Stefanatos et al.   CELL CYCLE

A novel signaling pathway in TNFα-induced neutrophil apoptosis

(2011) Barbara Geering et al.   CELL CYCLE

A novel role of hydrogen peroxide in Kaposi sarcoma-associated herpesvirus reactivation

(2011) Fengchun Ye et al.   CELL CYCLE

Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover

(2011) S Rikka et al.   CELL DEATH AND DIFFERENTIATION

Structural and mechanistic basis of Parl activity and regulation

(2011) D V Jeyaraju et al.   CELL DEATH AND DIFFERENTIATION

Redox regulation and the metabolic syndrome

(2011) M Maccarrone et al.   CELL DEATH AND DIFFERENTIATION

Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins

(2011) S Torii et al.   CELL DEATH AND DIFFERENTIATION

miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition

(2011) A Magenta et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial fusion is regulated by Reaper to modulate Drosophila programmed cell death

(2011) M Thomenius et al.   CELL DEATH AND DIFFERENTIATION

Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia–reoxygenation stress

(2011) X Liu et al.   CELL DEATH AND DIFFERENTIATION

Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics and neuronal synaptic damage in neurodegenerative diseases

(2011) T Nakamura et al.   CELL DEATH AND DIFFERENTIATION

The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites

(2011) P Pinton et al.   CELL DEATH AND DIFFERENTIATION

Intracellular zinc release-activated ERK-dependent GSK-3β–p53 and Noxa–Mcl-1 signaling are both involved in cardiac ischemic-reperfusion injury

(2011) C-L Lin et al.   CELL DEATH AND DIFFERENTIATION

Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism

(2011) N Hagen et al.   CELL DEATH AND DIFFERENTIATION

Peculiarities of cell death mechanisms in neutrophils

(2011) B Geering et al.   CELL DEATH AND DIFFERENTIATION

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

(2011) U Weyemi et al.   ONCOGENE

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

(2011) D R Gough et al.   Cell Death & Disease

Trans-Plasma Membrane Electron Transport in Mammals: Functional Significance in Health and Disease

(2010) Domenico Del Principe et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of senescence and aging characteristics by mitochondrially generated ROS: How are they linked?

(2010) John Papaconstantinou et al.   CELL CYCLE

Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma

(2010) Carole Sourbier et al.   CELL CYCLE

Differential localization of ATM is correlated with activation of distinct downstream signaling pathways

(2010) Angela Alexander et al.   CELL CYCLE

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death

(2010) Y Tang et al.   CELL DEATH AND DIFFERENTIATION

CAML regulates Bim-dependent thymocyte death

(2010) C E Edgar et al.   CELL DEATH AND DIFFERENTIATION

Prostaglandins antagonistically control Bax activation during apoptosis

(2010) L Lalier et al.   CELL DEATH AND DIFFERENTIATION

TNF-α-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-XL

(2010) J J Kim et al.   CELL DEATH AND DIFFERENTIATION

The microRNA and p53 families join forces against cancer

(2010) N A Barlev et al.   CELL DEATH AND DIFFERENTIATION

BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane

(2010) Z T Schug et al.   CELL DEATH AND DIFFERENTIATION

p22phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation

(2010) J L Sardina et al.   CELL DEATH AND DIFFERENTIATION

GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria

(2010) K John et al.   CELL DEATH AND DIFFERENTIATION

A positive role for c-Abl in Atm and Atr activation in DNA damage response

(2010) X Wang et al.   CELL DEATH AND DIFFERENTIATION

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

(2010) S Tobaben et al.   CELL DEATH AND DIFFERENTIATION

PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation

(2010) J-J Lee et al.   CELL DEATH AND DIFFERENTIATION

Interferon-stimulated gene ISG12b2 is localized to the inner mitochondrial membrane and mediates virus-induced cell death

(2010) M-Y Lu et al.   CELL DEATH AND DIFFERENTIATION

p53-family proteins and their regulators: hubs and spokes in tumor suppression

(2010) L Collavin et al.   CELL DEATH AND DIFFERENTIATION

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

(2010) S Ben Mkaddem et al.   CELL DEATH AND DIFFERENTIATION

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

(2010) L Bouman et al.   CELL DEATH AND DIFFERENTIATION

Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction

(2010) A Lemarie et al.   CELL DEATH AND DIFFERENTIATION

Tunneling-nanotube development in astrocytes depends on p53 activation

(2010) Y Wang et al.   CELL DEATH AND DIFFERENTIATION

Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

(2010) A Morizot et al.   CELL DEATH AND DIFFERENTIATION

Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells

(2010) M L Marino et al.   Cell Death & Disease

Roles of Nox1 and other Nox isoforms in cancer development

(2009) Tohru Kamata   CANCER SCIENCE

Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2

(2009) Z X Chen et al.   CELL DEATH AND DIFFERENTIATION

Caspase-dependent generation of reactive oxygen species in human astrocytoma cells contributes to resistance to TRAIL-mediated apoptosis

(2009) K Choi et al.   CELL DEATH AND DIFFERENTIATION

Dual roles of Drosophila p53 in cell death and cell differentiation

(2009) Y Fan et al.   CELL DEATH AND DIFFERENTIATION

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding

(2009) N D Marchenko et al.   CELL DEATH AND DIFFERENTIATION

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

The dark side of a tumor suppressor: anti-apoptotic p53

(2008) R U Jänicke et al.   CELL DEATH AND DIFFERENTIATION

Nox-generated ROS modulate glucose uptake in a leukaemic cell line

(2008) Cecilia Prata et al.   FREE RADICAL RESEARCH

Biological Roles for the NOX Family NADPH Oxidases

(2008) William M. Nauseef   JOURNAL OF BIOLOGICAL CHEMISTRY