- Home
- Publications
- Publication Search
- Publication Details
Title
Metformin as Potential Therapy for High-Grade Glioma
Authors
Keywords
-
Journal
Cancers
Volume 12, Issue 1, Pages 210
Publisher
MDPI AG
Online
2020-01-17
DOI
10.3390/cancers12010210
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Obesity as a tumour development triggering factor
- (2019) Agnieszka Budny et al. ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE
- Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation
- (2019) Shuai Zhang et al. Cell Death & Disease
- Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis
- (2019) Corinna Seliger et al. INTERNATIONAL JOURNAL OF CANCER
- Mitochondrial electron transport chain, ROS generation and uncoupling (Review)
- (2019) Ru‑Zhou Zhao et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Serum iron, Magnesium, Copper, and Manganese Levels in Alcoholism: A Systematic Review
- (2019) Cezary Grochowski et al. MOLECULES
- Metformin inhibits progression of Head and Neck Squamous Cell Carcinoma by acting Directly on Carcinoma Initiating Cells
- (2019) Xingyu Wu et al. CANCER RESEARCH
- Effect of metformin on cell proliferation, apoptosis, migration and invasion in A172 glioma cells and its mechanisms
- (2019) Zhang Xiong et al. Molecular Medicine Reports
- Role of Metformin and AKT Axis Modulation in the Reversion of Hypoxia Induced TMZ-Resistance in Glioma Cells
- (2019) Alessia Lo Dico et al. Frontiers in Oncology
- The induction of HAD-like phosphatases by multiple signaling pathways confers resistance to the metabolic inhibitor 2-deoxyglucose
- (2019) Quentin Defenouillère et al. Science Signaling
- PD-L1/PD-1 Axis in Glioblastoma Multiforme
- (2019) Jakub Litak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metformin enhances antitumor action of sodium dichloroacetate against glioma C6
- (2019) D.L. Kolesnik et al. Experimental Oncology
- The role of aquaporin-4 in synaptic plasticity, memory and disease
- (2018) Jacqueline A. Hubbard et al. BRAIN RESEARCH BULLETIN
- Neural stem cell therapy - brief review
- (2018) Cezary Grochowski et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Metformin's antitumour and anti-angiogenic activities are mediated by skewing macrophage polarization
- (2018) Ji-Chang Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Size and location correlations with higher rupture risk of intracranial aneurysms
- (2018) Cezary Grochowski et al. JOURNAL OF CLINICAL NEUROSCIENCE
- AMP kinase promotes glioblastoma bioenergetics and tumour growth
- (2018) Rishi Raj Chhipa et al. NATURE CELL BIOLOGY
- Disruption of Intracellular ATP Generation and Tight Junction Protein Expression during the Course of Brain Edema Induced by Subacute Poisoning of 1,2-Dichloroethane
- (2018) Gaoyang Wang et al. Frontiers in Neuroscience
- Immune Microenvironment in Glioblastoma Subtypes
- (2018) Zhihong Chen et al. Frontiers in Immunology
- Use of metformin and survival of patients with high-grade glioma
- (2018) Corinna Seliger et al. INTERNATIONAL JOURNAL OF CANCER
- Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma
- (2018) Valeria Gerthofer et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
- (2018) Jong-Ho Cha et al. MOLECULAR CELL
- Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo
- (2018) Yanmin Wang et al. OncoTargets and Therapy
- Metformin — a new old drug
- (2017) Marta Patrycja Wróbel et al. Endokrynologia Polska
- In vitro antiglioma action of indomethacin is mediated via AMP-activated protein kinase/mTOR complex 1 signalling pathway
- (2017) Aleksandar Pantovic et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Metformin and cancer in type 2 diabetes: a systematic review and comprehensive bias evaluation
- (2017) Ruth E Farmer et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Systematic review and meta-analysis of the effect of metformin treatment on overall mortality rates in women with endometrial cancer and type 2 diabetes mellitus
- (2017) Faustino R. Perez-Lopez et al. MATURITAS
- Ultra high field TOF-MRA: A method to visualize small cerebral vessels. 7 T TOF-MRA sequence parameters on different MRI scanners – Literature review
- (2017) Cezary Grochowski et al. Neurologia i Neurochirurgia Polska
- Metformin – its potential anti-cancer and anti-aging effects
- (2017) Monika Podhorecka et al. Postepy Higieny I Medycyny Doswiadczalnej
- A review for clinicians: Prostate cancer and the antineoplastic properties of metformin
- (2017) Stephen J. Hankinson et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis
- (2017) Natalia Rukoyatkina et al. Cell Death & Disease
- Progress in the application and mechanism of metformin in treating non-small cell lung cancer
- (2017) Chan Li et al. Oncology Letters
- Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling
- (2017) Chi-Fu Chiang et al. Oncotarget
- Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models
- (2017) Silvia Valtorta et al. Oncotarget
- Metformin in Lung Cancer: Review of in Vitro and in Vivo Animal Studies
- (2017) Michael Yousef et al. Cancers
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes
- (2016) Nisa M. Maruthur et al. ANNALS OF INTERNAL MEDICINE
- Functional characterization of AMP-activated protein kinase signaling in tumorigenesis
- (2016) Ji Cheng et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines
- (2016) Mona M. Saber et al. BMC CANCER
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2
- (2016) Corinna Seliger et al. CELL CYCLE
- Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson’s Disease, Glioma, and Schwannoma
- (2016) Justin Hall et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Targeting Protein-Protein Interactions in the HIF System
- (2016) Sarah E. Wilkins et al. ChemMedChem
- PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity
- (2016) J. Incio et al. CLINICAL CANCER RESEARCH
- Effect of diclofenac on SLC16A3/MCT4 by the Caco-2 cell line
- (2016) Shotaro Sasaki et al. Drug Metabolism and Pharmacokinetics
- Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma
- (2016) KOJI HARADA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- IDH mutation is associated with higher risk of malignant transformation in low-grade glioma
- (2016) Severina Leu et al. JOURNAL OF NEURO-ONCOLOGY
- Metformin-associated lactic acidosis: Current perspectives on causes and risk
- (2016) Ralph DeFronzo et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
- (2016) Xianli Shen et al. NATURE IMMUNOLOGY
- Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin
- (2016) Eui Hyun Kim et al. NEURO-ONCOLOGY
- Metformin potentiates the anticancer activities of gemcitabine and cisplatin against cholangiocarcinoma cells in vitro and in vivo
- (2016) Hua-Qiang Zhu et al. ONCOLOGY REPORTS
- Anti-tumor effects of metformin on head and neck carcinoma cell lines: A systematic review
- (2016) Daniela Fortunato Rêgo et al. Oncology Letters
- Temozolomide in combination with metformin act synergistically to inhibit proliferation and expansion of glioma stem-like cells
- (2016) ZHIYUN YU et al. Oncology Letters
- Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells
- (2016) Bo Li et al. Oncotarget
- Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma
- (2016) Wei Jiang et al. Oncotarget
- Metformin treatment reduces temozolomide resistance of glioblastoma cells
- (2016) Seung Ho Yang et al. Oncotarget
- Metformin and gefitinib cooperate to inhibit bladder cancer growth via both AMPK and EGFR pathways joining at Akt and Erk
- (2016) Mei Peng et al. Scientific Reports
- Metformin Action: Concentrations Matter
- (2015) Ling He et al. Cell Metabolism
- Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model
- (2015) A. Lo Dico et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Mathematical model of the effect of ischemia–reperfusion on brain capillary collapse and tissue swelling
- (2015) M.J. Mohamed Mokhtarudin et al. MATHEMATICAL BIOSCIENCES
- Diabetes, use of antidiabetic drugs, and the risk of glioma
- (2015) Corinna Seliger et al. NEURO-ONCOLOGY
- Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors
- (2015) Jeanette E. Eckel-Passow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molekulare Diagnostik in der Neuropathologie
- (2015) W. Dietmaier et al. PATHOLOGE
- Immune-mediated antitumor effect by type 2 diabetes drug, metformin
- (2015) Shingo Eikawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin influences progression in diabetic glioblastoma patients
- (2015) Sebastian Adeberg et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice
- (2015) Pinghui Jie et al. Frontiers in Cellular Neuroscience
- The Blood–Brain Barrier
- (2015) Richard Daneman et al. Cold Spring Harbor Perspectives in Biology
- Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype
- (2015) Elisabet Cuyàs et al. Oncotarget
- Metformin prevents cancer metastasis by inhibiting M2-like polarization of tumor associated macrophages
- (2015) Ling Ding et al. Oncotarget
- Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo
- (2015) Zhiyun Yu et al. Oncotarget
- Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
- (2015) Julie Sesen et al. PLoS One
- Unknown
- (2015) Elisabet Cuyàs et al. Oncotarget
- Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current
- (2015) Marta Gritti et al. Oncotarget
- Invasive Glioblastoma Cells Acquire Stemness and Increased Akt Activation
- (2015) Jennifer R. Molina et al. NEOPLASIA
- Metabolic Targeting of Lactate Efflux by Malignant Glioma Inhibits Invasiveness and Induces Necrosis: An In Vivo Study
- (2015) Chaim B Colen et al. NEOPLASIA
- Cisplatin Combined with Metformin Inhibits Migration and Invasion of Human Nasopharyngeal Carcinoma Cells by Regulating E-cadherin and MMP-9
- (2014) Xiao-Jin Sun et al. Asian Pacific Journal of Cancer Prevention
- The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation
- (2014) Remco J. Molenaar et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation
- (2014) G Cheng et al. BRITISH JOURNAL OF CANCER
- The biguanides metformin and phenformin inhibit angiogenesis, local and metastatic growth of breast cancer by targeting both neoplastic and microenvironment cells
- (2014) Stefania Orecchioni et al. INTERNATIONAL JOURNAL OF CANCER
- Metformin decreases IL-22 secretion to suppress tumor growth in an orthotopic mouse model of hepatocellular carcinoma
- (2014) Dong Zhao et al. INTERNATIONAL JOURNAL OF CANCER
- P17.39 * TURN OLD INTO NEW: METFORMIN AS ANTINEOPLASTIC AGENT IN GLIOBLASTOMA
- (2014) C. Seliger et al. NEURO-ONCOLOGY
- The Neurology of mTOR
- (2014) Jonathan O. Lipton et al. NEURON
- Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide
- (2014) Krzysztof Łabuzek et al. Pharmacological Reports
- Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK
- (2014) X. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Radiosensitization of Pancreatic Cancer Cells by Metformin through the AMPK Pathway
- (2014) Aisha Fasih et al. RADIATION RESEARCH
- Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme
- (2014) Arnulf Mayer et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment
- (2014) D Ciavardelli et al. Cell Death & Disease
- Understanding and Targeting Alkylator Resistance in Glioblastoma
- (2014) W. Wick et al. Cancer Discovery
- Evaluation of the Protective Potential of Brain Microvascular Endothelial Cell Autophagy on Blood–Brain Barrier Integrity During Experimental Cerebral Ischemia–Reperfusion Injury
- (2014) Haiying Li et al. Translational Stroke Research
- New Molecules and Old Drugs as Emerging Approaches to Selectively Target Human Glioblastoma Cancer Stem Cells
- (2014) Roberto Würth et al. Biomed Research International
- Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
- (2014) William W Wheaton et al. eLife
- Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo
- (2013) Nadine Jetten et al. ANGIOGENESIS
- Metformin induces up-regulation of blood–brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells
- (2013) Fuyuko Takata et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Biology of AQP4 and Anti-AQP4 Antibody: Therapeutic Implications for NMO
- (2013) A. S. Verkman et al. BRAIN PATHOLOGY
- Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK
- (2013) Y Storozhuk et al. BRITISH JOURNAL OF CANCER
- Differential sensitivities of glioblastoma cell lines towards metabolic and signaling pathway inhibitions
- (2013) Colin R. Kennedy et al. CANCER LETTERS
- Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism
- (2013) S.-M. Fendt et al. CANCER RESEARCH
- AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors
- (2013) M. Rios et al. CANCER RESEARCH
- Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
- (2013) Madhusudhanan Sukumar et al. JOURNAL OF CLINICAL INVESTIGATION
- Potential applications for biguanides in oncology
- (2013) Michael Pollak JOURNAL OF CLINICAL INVESTIGATION
- Metformin inhibits glioma cell U251 invasion by downregulation of fibulin-3
- (2013) Lian-Bo Gao et al. NEUROREPORT
- Non-Steroidal Anti-inflammatory Drugs Decrease E2F1 Expression and Inhibit Cell Growth in Ovarian Cancer Cells
- (2013) Blanca L. Valle et al. PLoS One
- New Aspects of an Old Drug – Diclofenac Targets MYC and Glucose Metabolism in Tumor Cells
- (2013) Eva Gottfried et al. PLoS One
- Vascularization Pattern After Ischemic Stroke is Different in Control Versus Diabetic Rats
- (2013) Roshini Prakash et al. STROKE
- Metformin improves healthspan and lifespan in mice
- (2013) Alejandro Martin-Montalvo et al. Nature Communications
- Metformin: an old but still the best treatment for type 2 diabetes
- (2013) Lilian Beatriz Aguayo Rojas et al. Diabetology & Metabolic Syndrome
- Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial
- (2013) David Preiss et al. Lancet Diabetes & Endocrinology
- Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- (2012) Dominik Sturm et al. CANCER CELL
- Metformin selectively affects human glioblastoma tumor-initiating cell viability
- (2012) Roberto Würth et al. CELL CYCLE
- Diclofenac inhibits lactate formation and efficiently counteracts local immune suppression in a murine glioma model
- (2012) Sridhar R. Chirasani et al. INTERNATIONAL JOURNAL OF CANCER
- Recent advances in the molecular understanding of glioblastoma
- (2012) Fonnet E. Bleeker et al. JOURNAL OF NEURO-ONCOLOGY
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets
- (2012) Vera Miranda-Gonçalves et al. NEURO-ONCOLOGY
- Ischemia–reperfusion impairs blood–brain barrier function and alters tight junction protein expression in the ovine fetus
- (2012) X. Chen et al. NEUROSCIENCE
- Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
- (2012) W-Y Shi et al. Cell Death & Disease
- Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning
- (2012) Michael N. Pollak Cancer Discovery
- Genetics of adult glioma
- (2012) McKinsey L. Goodenberger et al. Cancer Genetics
- Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
- (2012) Chang W. Song et al. Scientific Reports
- Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK
- (2012) Atsushi Sato et al. Stem Cells Translational Medicine
- Regulation of Tight Junctions in Upper Airway Epithelium
- (2012) Takashi Kojima et al. Biomed Research International
- Glioma-related edema: new insight into molecular mechanisms and their clinical implications
- (2012) Zhi-Xiong Lin Chinese Journal of Cancer
- Can the therapeutic effects of temozolomide be potentiated by stimulating AMP-activated protein kinase with olanzepine and metformin?
- (2011) RE Kast et al. BRITISH JOURNAL OF PHARMACOLOGY
- Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells
- (2011) B. Bao et al. Cancer Prevention Research
- Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
- (2011) I. Ben Sahra et al. CANCER RESEARCH
- Cancer mortality reduction and metformin: a retrospective cohort study in type 2 diabetic patients
- (2011) S. Bo et al. DIABETES OBESITY & METABOLISM
- The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
- (2011) Rasheduzzaman Chowdhury et al. EMBO REPORTS
- In vitro and in vivo anti-melanoma action of metformin
- (2011) Kristina Janjetovic et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Temozolomide induced c-Myc-mediated apoptosisviaAkt signalling in MGMT expressing glioblastoma cells
- (2011) Maria De Salvo et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Specific Role of Tight Junction Proteins Claudin-5, Occludin, and ZO-1 of the Blood–Brain Barrier in a Focal Cerebral Ischemic Insult
- (2011) Haixia Jiao et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Type 2 diabetes mellitus and obesity are independent risk factors for poor outcome in patients with high-grade glioma
- (2011) Lola B. Chambless et al. JOURNAL OF NEURO-ONCOLOGY
- AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications
- (2011) C Grimaldi et al. LEUKEMIA
- Dual Inhibition of Tumor Energy Pathway by 2-Deoxyglucose and Metformin Is Effective against a Broad Spectrum of Preclinical Cancer Models
- (2011) J.-H. Cheong et al. MOLECULAR CANCER THERAPEUTICS
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Targeting cancer metabolism: a therapeutic window opens
- (2011) Matthew G. Vander Heiden NATURE REVIEWS DRUG DISCOVERY
- FoxO3a Functions as a Key Integrator of Cellular Signals that Control Glioblastoma Stem-Like Cell Differentiation and Tumorigenicity
- (2011) Jun Sunayama et al. STEM CELLS
- Metformin inhibits melanoma development through autophagy and apoptosis mechanisms
- (2011) T Tomic et al. Cell Death & Disease
- Metformin Use and Mortality Among Patients With Diabetes and AtherothrombosisMetformin Use With Diabetes and Atherothrombosis
- (2010) Ronan Roussel ARCHIVES OF INTERNAL MEDICINE
- Caspase-3 and Bcl-2 expression in glioblastoma: an immunohistochemical study
- (2010) Luís Fernando Tirapelli et al. ARQUIVOS DE NEURO-PSIQUIATRIA
- The combination of metformin and 2 deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells
- (2010) Issam Ben Sahra et al. Autophagy
- The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
- (2010) A. S. Green et al. BLOOD
- Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells
- (2010) Mahvash Zakikhani et al. BREAST CANCER RESEARCH AND TREATMENT
- The human side of hypoxia-inducible factor
- (2010) Thomas G. Smith et al. BRITISH JOURNAL OF HAEMATOLOGY
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- 2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion
- (2010) Haibin Xi et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis
- (2010) R. M. Memmott et al. Cancer Prevention Research
- Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
- (2010) Adem Kalender et al. Cell Metabolism
- Metformin and Cancer Occurrence in Insulin-Treated Type 2 Diabetic Patients
- (2010) M. Monami et al. DIABETES CARE
- Glucose-lowering agents and cancer mortality rates in type 2 diabetes: assessing effects of time-varying exposure
- (2010) S. L. Bowker et al. DIABETOLOGIA
- Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics
- (2010) Rita A Mukhtar et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- 5′-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat
- (2010) Taichang Jang et al. INTERNATIONAL JOURNAL OF CANCER
- Activation of AMP-activated Protein Kinase by Temozolomide Contributes to Apoptosis in Glioblastoma Cells via p53 Activation and mTORC1 Inhibition
- (2010) Wen-bin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AQP-4 in peritumoral edematous tissue is correlated with the degree of glioma and with expression of VEGF and HIF-alpha
- (2010) Kejie Mou et al. JOURNAL OF NEURO-ONCOLOGY
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- Metabolic Modulation of Glioblastoma with Dichloroacetate
- (2010) E. D. Michelakis et al. Science Translational Medicine
- Cancer stem cells in solid tumors
- (2010) Patrick C. Hermann et al. SEMINARS IN CANCER BIOLOGY
- Non-steroidal anti-inflammatory drugs and risk of gastric and oesophageal adenocarcinomas: results from a cohort study and a meta-analysis
- (2009) C C Abnet et al. BRITISH JOURNAL OF CANCER
- New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes
- (2009) G. Libby et al. DIABETES CARE
- Global estimates of the prevalence of diabetes for 2010 and 2030
- (2009) J.E. Shaw et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A–DDB1 ubiquitin ligase
- (2009) Samiksha Katiyar et al. EMBO REPORTS
- Monocarboxylate transport in human corneal epithelium and cell lines
- (2009) Kati-Sisko Vellonen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner
- (2009) R. Rattan et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Association Between Hyperglycemia and Survival in Patients With Newly Diagnosed Glioblastoma
- (2009) Rachel L. Derr et al. JOURNAL OF CLINICAL ONCOLOGY
- Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis
- (2009) N. Nath et al. JOURNAL OF IMMUNOLOGY
- Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells
- (2009) G. L. Gallia et al. MOLECULAR CANCER THERAPEUTICS
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomas
- (2009) Kaisorn L. Chaichana et al. NEUROLOGICAL RESEARCH
- Aquaporin-4 in brain and spinal cord oedema
- (2009) S. Saadoun et al. NEUROSCIENCE
- PERSISTENT OUTPATIENT HYPERGLYCEMIA IS INDEPENDENTLY ASSOCIATED WITH DECREASED SURVIVAL AFTER PRIMARY RESECTION OF MALIGNANT BRAIN ASTROCYTOMAS
- (2009) Matthew J. McGirt et al. NEUROSURGERY
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Metformin: safety in cardiac patients
- (2009) R. Khurana et al. POSTGRADUATE MEDICAL JOURNAL
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Physiology and Function of the Tight Junction
- (2009) J. M. Anderson et al. Cold Spring Harbor Perspectives in Biology
- Optimized Proteomic Analysis on Gels of Cell−Cell Adhering Junctional Membrane Proteins†
- (2008) Yuji Yamazaki et al. BIOCHEMISTRY
- Tumor Cell Metabolism: Cancer's Achilles' Heel
- (2008) Guido Kroemer et al. CANCER CELL
- Metformin therapy and clinical uses
- (2008) John HB Scarpello et al. Diabetes & Vascular Disease Research
- Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy
- (2008) D. M. Nathan et al. DIABETOLOGIA
- Metformin inhibits TNF-α-induced IκB kinase phosphorylation, IκB-α degradation and IL-6 production in endothelial cells through PI3K-dependent AMPK phosphorylation
- (2008) Nan-Lan Huang et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Immunohistochemical localization of caspase-3, caspase-9 and Bax in U87 glioblastoma xenografts
- (2008) Otilia Zarnescu et al. JOURNAL OF MOLECULAR HISTOLOGY
- Bradykinin increases blood–tumor barrier permeability by down-regulating the expression levels of ZO-1, occludin, and claudin-5 and rearranging actin cytoskeleton
- (2008) Li-bo Liu et al. JOURNAL OF NEUROSCIENCE RESEARCH
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- AKT Is Activated in an Ataxia-Telangiectasia and Rad3-Related-Dependent Manner in Response to Temozolomide and Confers Protection against Drug-Induced Cell Growth Inhibition
- (2008) S. Caporali et al. MOLECULAR PHARMACOLOGY
- Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice
- (2008) E B Rankin et al. ONCOGENE
- Brain Cancer Stem Cells Display Preferential Sensitivity to Akt Inhibition
- (2008) Christine E. Eyler et al. STEM CELLS
- Cancer stem cells and glioma
- (2008) Sunit Das et al. Nature clinical practice. Neurology
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now