The biguanides metformin and phenformin inhibit angiogenesis, local and metastatic growth of breast cancer by targeting both neoplastic and microenvironment cells
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Title
The biguanides metformin and phenformin inhibit angiogenesis, local and metastatic growth of breast cancer by targeting both neoplastic and microenvironment cells
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF CANCER
Volume 136, Issue 6, Pages E534-E544
Publisher
Wiley
Online
2014-09-06
DOI
10.1002/ijc.29193
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Note: Only part of the references are listed.- If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice
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- (2014) Katiuscia Dallaglio et al. CARCINOGENESIS
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- (2014) Cristina Oliveras-Ferraros et al. CELL CYCLE
- Molecular Pathways: Preclinical Models and Clinical Trials with Metformin in Breast Cancer
- (2014) A. M. Thompson CLINICAL CANCER RESEARCH
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- Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
- (2014) Kıvanç Birsoy et al. NATURE
- Metformin—mode of action and clinical implications for diabetes and cancer
- (2014) Ida Pernicova et al. Nature Reviews Endocrinology
- Human Adipose Tissue-Derived Stromal/Stem Cells Promote Migration and Early Metastasis of Triple Negative Breast Cancer Xenografts
- (2014) Brian G. Rowan et al. PLoS One
- Metformin Induces Apoptosis and Cell Cycle Arrest Mediated by Oxidative Stress, AMPK and FOXO3a in MCF-7 Breast Cancer Cells
- (2014) Eveline A. I. F. Queiroz et al. PLoS One
- The effect of metformin on apoptosis in a breast cancer presurgical trial
- (2013) M Cazzaniga et al. BRITISH JOURNAL OF CANCER
- Metformin Selectively Targets Tumor-Initiating Cells in ErbB2-Overexpressing Breast Cancer Models
- (2013) P. Zhu et al. Cancer Prevention Research
- Metformin Inhibits Skin Tumor Promotion in Overweight and Obese Mice
- (2013) L. A. Checkley et al. Cancer Prevention Research
- Complementary Populations of Human Adipose CD34+ Progenitor Cells Promote Growth, Angiogenesis, and Metastasis of Breast Cancer
- (2013) S. Orecchioni et al. CANCER RESEARCH
- Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response
- (2013) V. E. Zannella et al. CLINICAL CANCER RESEARCH
- Synergistic Effects of Metformin Treatment in Combination with Gefitinib, a Selective EGFR Tyrosine Kinase Inhibitor, in LKB1 Wild-type NSCLC Cell Lines
- (2013) F. Morgillo et al. CLINICAL CANCER RESEARCH
- Potential applications for biguanides in oncology
- (2013) Michael Pollak JOURNAL OF CLINICAL INVESTIGATION
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- (2013) David Margel et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2013) César Nombela-Arrieta et al. NATURE CELL BIOLOGY
- Metformin Is Associated With Survival Benefit in Cancer Patients With Concurrent Type 2 Diabetes: A Systematic Review and Meta-Analysis
- (2013) M. Yin et al. ONCOLOGIST
- Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
- (2013) H. A. Hirsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin improves healthspan and lifespan in mice
- (2013) Alejandro Martin-Montalvo et al. Nature Communications
- Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study
- (2012) Saroj Niraula et al. BREAST CANCER RESEARCH AND TREATMENT
- Phenformin as prophylaxis and therapy in breast cancer xenografts
- (2012) M V C L Appleyard et al. BRITISH JOURNAL OF CANCER
- Stromal Progenitor Cells from Endogenous Adipose Tissue Contribute to Pericytes and Adipocytes That Populate the Tumor Microenvironment
- (2012) Y. Zhang et al. CANCER RESEARCH
- Metformin is synthetically lethal with glucose withdrawal in cancer cells
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- (2012) Roberto Würth et al. CELL CYCLE
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- (2012) Jessica J. Shank et al. GYNECOLOGIC ONCOLOGY
- Diabetes, Metformin, and Breast Cancer: Lilac Time?
- (2012) Pamela J. Goodwin et al. JOURNAL OF CLINICAL ONCOLOGY
- Origins of the Tumor Microenvironment: Quantitative Assessment of Adipose-Derived and Bone Marrow–Derived Stroma
- (2012) Shannon Kidd et al. PLoS One
- Implanted adipose progenitor cells as physicochemical regulators of breast cancer
- (2012) E. M. Chandler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC
- (2012) Giovanni Blandino et al. Nature Communications
- Understanding the benefit of metformin use in cancer treatment
- (2011) Ryan JO Dowling et al. BMC Medicine
- Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial
- (2011) Sirwan Hadad et al. BREAST CANCER RESEARCH AND TREATMENT
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
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- (2011) I. Martin-Padura et al. CANCER RESEARCH
- Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis
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